CAS 102394-31-0

11-[2-[2-[(Dietilamino)metil]-1-piperidinil]acetil]-5,11-diidro-6H-pirido[2,3-b][1,4]benzodiazepin-6-one

Descrizione:

La sostanza chimica nota come 11-[2-[2-[(Dietilamino)metil]-1-piperidinil]acetil]-5,11-diidro-6H-pirido[2,3-b][1,4]benzodiazepin-6-one, con il numero CAS 102394-31-0, è un composto organico complesso che appartiene alla classe delle benzodiazepine. Presenta una struttura multiciclica che include un moiety di pirido e benzodiazepina, che contribuisce alle sue proprietà farmacologiche. La presenza di un gruppo dietilamino suggerisce potenziali interazioni con i sistemi di neurotrasmettitori, in particolare nel sistema nervoso centrale. Questo composto può mostrare varie attività biologiche, inclusi effetti ansiolitici o sedativi, tipici delle benzodiazepine, sebbene siano necessari dati farmacologici specifici per confermare la sua efficacia e il profilo di sicurezza. La sua struttura intricata indica che può attraversare vari percorsi metabolici, influenzando la sua biodisponibilità e emivita. Come molti composti di questa classe, è essenziale considerare attentamente le sue proprietà chimiche, come solubilità, stabilità e reattività, per la sua applicazione in chimica medicinale e nello sviluppo di farmaci.

Formula: C₂₄H₃₁N₅O₂

InChI: InChI=1S/C24H31N5O2/c1-3-27(4-2)16-18-10-7-8-15-28(18)17-22(30)29-21-13-6-5-11-19(21)24(31)26-20-12-9-14-25-23(20)29/h5-6,9,11-14,18H,3-4,7-8,10,15-17H2,1-2H3,(H,26,31)

InChI key: InChIKey=UBRKDAVQCKZSPO-UHFFFAOYSA-N

SMILES: C(CN1C(CN(CC)CC)CCCC1)(=O)N2C=3C(C(=O)NC=4C2=NC=CC4)=CC=CC3

Sinonimi:

• 11-((2-((Diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-(6H)-pyrido[2.3-b][1.4]benzodiazepin-6-one
• 11-[2-[2-(Diethylaminomethyl)piperidin-1-yl]acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one
• 11-[2-[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
• 6H-Pyrido(2,3-B)(1,4)Benzodiazepin-6-One,5,11-Dihydro-11-((2-((Diethylamino)M
• 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 11-[2-[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-
• 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 11-[[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-
• Af-Dx 116
• Ethyl)-7-Piperidinyl)Acetyl)-
• Otenzepad

6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 11-[2-[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-

CAS: 102394-31-0

Formula: C₂₄H₃₁N₅O₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 421.5352

Ref: IN-DA0007BO

Otenzepad

CAS: 102394-31-0

Otenzepad

Purezza: ≥98%

Peso molecolare: 421.54g/mol

Ref: 54-BUP05581

AF-DX 116

Prodotto controllato

CAS: 102394-31-0

Formula: C₂₄H₃₁N₅O₂

Colore e forma: Neat

Peso molecolare: 421.535

Ref: TR-A355358

Otenzepad

CAS: 102394-31-0

Otenzepad is a fluorescent probe that can bind to muscarinic receptors and be used as a research tool. It is an antagonist of the muscarinic receptor, which inhibits the neurotransmitter acetylcholine from binding to the receptor. Otenzepad has low potency and is not selective for any one type of muscarinic receptor, but it does have high affinity for all types. Otenzepad binds to cholinergic neurons by competitive inhibition, preventing acetylcholine from binding to the receptor and inhibiting their function. This results in decreased production of other chemicals that are important for memory and learning processes. Atropine and pirenzepine are muscarinic antagonists that are used in medical practice as anticholinergics or antispasmodics. They block acetylcholine receptors on smooth muscle cells, leading to increased bladder contraction and reduced gastrointestinal motility. Estrogen-benzoate also has antagonistic effects on the muscarinic

Formula: C₂₄H₃₁N₅O₂

Purezza: Min. 95%

Peso molecolare: 421.54 g/mol

Ref: 3D-CEA39431

Otenzepad

CAS: 102394-31-0

Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.

Formula: C₂₄H₃₁N₅O₂

Purezza: 99.79%

Colore e forma: Solid

Peso molecolare: 421.54

Ref: TM-T16411