CAS 10246-75-0

idrossizina pamoato

Descrizione:

idrossizina pamoato è un farmaco utilizzato principalmente per le sue proprietà antistaminiche e ansiolitiche. È una forma salina della idrossizina, che è un antistaminico in grado di alleviare i sintomi di allergie, ansia e nausea. Il sale pamoato ne migliora la solubilità e la biodisponibilità. idrossizina pamoato viene tipicamente somministrato per via orale ed è noto per i suoi effetti sedativi, rendendolo utile nel trattamento dei disturbi d'ansia e come premedicazione per procedure chirurgiche. Il composto presenta un peso molecolare relativamente alto ed è caratterizzato dalla sua capacità di attraversare la barriera ematoencefalica, contribuendo ai suoi effetti sul sistema nervoso centrale. È importante notare che idrossizina pamoato può causare effetti collaterali come sonnolenza, secchezza delle fauci e vertigini. Come per qualsiasi farmaco, deve essere utilizzato sotto la guida di un professionista sanitario, considerando le potenziali interazioni con altri farmaci e i fattori individuali del paziente.

Formula: C₂₃H₁₆O₆·C₂₁H₂₇ClN₂O₂

InChI: InChI=1S/C23H16O6.C21H27ClN2O2/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-10,24-25H,11H2,(H,26,27)(H,28,29);1-9,21,25H,10-17H2

InChI key: InChIKey=ASDOKGIIKXGMNB-UHFFFAOYSA-N

SMILES: C(C=1C2=C(C=C(C(O)=O)C1O)C=CC=C2)C=3C4=C(C=C(C(O)=O)C3O)C=CC=C4.C(N1CCN(CCOCCO)CC1)(C2=CC=C(Cl)C=C2)C3=CC=CC=C3

Sinonimi:

• 1-(p-Chloro-α-phenylbenzyl)-4-(2-hydroxyethoxyethyl)piperazine, pamoate
• 2-(2-(4-((4-Chlorophenyl)(Phenyl)Methyl)Piperazin-1-Yl)Ethoxy)Ethanol 4,4′-Methylenebis(3-Hydroxy-2-Naphthoate)
• 2-(2-{4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazin-1-Yl}Ethoxy)Ethanol
• 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-, compd. with 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethanol (1:1)
• 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, compd. with 2-[2-[4-(p-chloro-α-phenylbenzyl)-1-piperazinyl]ethoxy]ethanol (1:1)
• 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, hydroxyzine salt
• 4,4'-Methanediylbis(3-Hydroxynaphthalene-2-Carboxylic Acid) - 2-(2-{4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazin-1-Yl}Ethoxy)Ethanol (1:1)
• Atarax P
• Equipose
• Ethanol, 2-[2-[4-(p-chloro-α-phenylbenzyl)-1-piperazinyl]ethoxy]-, 4,4′-methylenebis[3-hydroxy-2-naphthoate] (1:1) (salt)
• Ethanol, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylate] (1:1)
• Hydroxyzine Embonate
• Hydroxyzyne pamoate
• Masmoran
• Paxisitil
• Paxistil
• Vistaril

Hydroxyzine Pamoate

CAS: 10246-75-0

Colore e forma: Neat

Ref: 61-FOR3107.00

Hydroxyzine Pamoate

CAS: 10246-75-0

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₂₁H₂₇ClN₂O₂·C₂₃H₁₆O₆

Colore e forma: Light Yellow Powder

Peso molecolare: 763.27

Ref: 45-1334006

Hydroxyzine pamoate

CAS: 10246-75-0

Formula: C₄₄H₄₃ClN₂O₈

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 763.2738

Ref: IN-DA007FBV

Hydroxyzine Pamoate

CAS: 10246-75-0

Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria and histamine-mediated pruritus.

Formula: C₄₄H₄₃ClN₂O₈

Purezza: 99.49%

Colore e forma: Solid

Peso molecolare: 763.27

Ref: TM-T0053

Hydroxyzine Pamoate

CAS: 10246-75-0

Hydroxyzine Pamoate

Purezza: ≥98%

Peso molecolare: 763.27g/mol

Ref: 54-BUP15032

Hydroxyzine Pamoate

Prodotto controllato

CAS: 10246-75-0

Formula: C₂₃H₁₆O₆·C₂₁H₂₇ClN₂O₂

Colore e forma: Neat

Peso molecolare: 763.27

Ref: 86-MM3107.00

Hydroxyzine pamoate

Prodotto controllato

CAS: 10246-75-0

Hydroxyzine pamoate is a drug that belongs to the group of H1 antagonists. It is used for the treatment of allergic reactions, bowel disease, and infectious diseases. Hydroxyzine pamoate has been shown to have a low potency in animals and humans, with a high incidence of side effects. This drug may act by competing with histamine at the receptor sites on mast cells or basophils. The matrix effect of this drug is unclear. Hydroxyzine pamoate has been shown to inhibit protein synthesis in some bacteria and can be used as an analytical method for detecting histamine in human blood samples.

Formula: C₄₄H₄₃ClN₂O₈

Purezza: Min. 95%

Colore e forma: White To Light (Or Pale) Yellow Solid

Peso molecolare: 763.27 g/mol

Ref: 3D-FH171674

Hydroxyzine Pamoate

CAS: 10246-75-0

Applications Hydroxyzine Pamoate is an H1 receptor antagonist. Anxiolytic. Antihistaminic.
References De Bruyn, T. et al.: Mol. Pharm., 83, 1257 (2013); Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Tsau, J., et al.: Anal. Profiles Drug Subs., 7, 319 (1978)

Formula: C₂₃H₁₆O₆·C₂₁H₂₇ClN₂O₂

Colore e forma: Neat

Peso molecolare: 763.27

Ref: TR-H996505

Hydroxyzine Pamoate

CAS: 10246-75-0

Formula: C₂₁H₂₇ClN₂O₂C₂₃H₁₆O₆

Peso molecolare: 374.9 : 388.4

Ref: ST-EA-CP-H11010