CAS 102625-64-9

Solfuro di pantoprazolo

Descrizione:

Solfuro di pantoprazolo, con il numero CAS 102625-64-9, è un composto chimico che è un derivato del pantoprazolo, un inibitore della pompa protonica comunemente usato per trattare la malattia da reflusso gastroesofageo (GERD) e altre condizioni legate all'eccesso di acido gastrico. Questo composto è caratterizzato dal suo gruppo funzionale sulfinile, che contribuisce alle sue proprietà farmacologiche. Solfuro di pantoprazolo è tipicamente un solido cristallino bianco a bianco sporco, che mostra bassa solubilità in acqua ma maggiore solubilità nei solventi organici. È noto per la sua stabilità in condizioni acide, essenziale per la sua funzione di inibizione della secrezione di acido gastrico. Il composto agisce legandosi in modo irreversibile alla pompa protonica nella mucosa gastrica, riducendo così la produzione di acido. La sua farmacocinetica implica un rapido assorbimento e metabolismo, principalmente nel fegato, portando ai suoi metaboliti attivi. Come per molti farmaci, la sicurezza e l'efficacia sono fondamentali, e Solfuro di pantoprazolo è soggetto a controllo normativo per garantire che soddisfi gli standard di salute per l'uso terapeutico.

Formula: C₁₆H₁₅F₂N₃O₃S

InChI: InChI=1/C16H15F2N3O3S/c1-22-13-5-6-19-12(14(13)23-2)8-25-16-20-10-4-3-9(24-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)

InChI key: InChIKey=UKILEIRWOYBGEJ-UHFFFAOYSA-N

SMILES: S(CC1=C(OC)C(OC)=CC=N1)C=2NC=3C(N2)=CC(OC(F)F)=CC3

Sinonimi:

• 1H-Benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-
• 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-
• 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridyl)methyl]thio]-1H-benzimidazole
• 5-(Difluoromethoxy)-2-{[( 3,4 Dimethoxypyridin-2-yl) methyl] thio}-1H-benzimidazolee
• 5-Difluoromethoxy-2-[(3,4-methoxy-2-pyridinylmethyl thio)-1H-benzimidozole
• 5-Diflyoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
• 6-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole
• 6-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole
• H 258/28
• Pantoprazole sulfide
• Pantoprazole thioether
• 5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole
• 5-(Difluoromethoxy)-2[[(3,4-dimethoxy-2-pyridinyl)methyl]-thio]-1H-benzimidazole
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulphanyl}-1H-benzimidazole
• 5-DIFLUOROMETHOXY-2-[(3,4-DIMETHOXY-2-PYRIDINYL)METHYL] THIO-1H-BENZIMIDAZOLE =98%
• 5-(Difluoromethoxy)-2-{[3,4-di
• 5-(DIFLUOROMETHOXY)-2-{[3,4-DIMETHOXY-2-PYRIDINYL)METHYL]THIO}IH-BENZIMIDAZOLE
• 5-DIFLUORMETHOXY-2[(3,4-DIMETHOXY-2-PRIDIXY)METHYLTHIO]-1H-BENZIMIDAZOLE
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxy-2-pyridinyl)-methyl]-thio}-1H-benzim
• 5-Difluoromethoxy-2-(((3,4-Dimethoxy-2-pyridinyl)methyl)thio)-1H-Benzimidazole (Pantaprazole intermediate)
• 5-Difluoromethoxy-2-{[(3,4-dim
• 5-(DIFLUOROMETHOXY)-2-[[3,4-DIMETHOXY-2-PYRIDINYL)-METHYL]-THIO]-1H-BENZIMIDAZOLE (PANTOPRAZOLE SULPHIDE COMPOUND)
• 5-Difluoromethoxy-2-(3,4-dimethoxy-pyridin-2-ylmethylsulfanyl)-1H-benzoimidazole
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

Pantoprazole Sulfide

CAS: 102625-64-9

Formula: C₁₆H₁₅F₂N₃O₃S

Purezza: >98.0%(T)(HPLC)

Colore e forma: Light orange to Light red powder to crystal

Peso molecolare: 367.37

Ref: 3B-P2066

Pantoprazole Related Compound B (5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole)

CAS: 102625-64-9

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₆H₁₅F₂N₃O₃S

Colore e forma: Off-White Light Brown Crystalline Powder

Peso molecolare: 367.08022

Ref: 45-1494910

1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-

CAS: 102625-64-9

Formula: C₁₆H₁₅F₂N₃O₃S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 367.3704

Ref: IN-DA0007YM

Pantoprazole EP Impurity B (Pantoprazole USP Related Compound B, Pantoprazole Sulfide)

CAS: 102625-64-9

Formula: C₁₆H₁₅F₂N₃O₃S

Colore e forma: Off-White Solid

Peso molecolare: 367.37

Ref: 4Z-P-0111

5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

CAS: 102625-64-9

5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

Purezza: 98%+

Peso molecolare: 367.37g/mol

Ref: 54-PC3237

Pantoprazole EP Impurity B

Prodotto controllato

CAS: 102625-64-9

Formula: C₁₆H₁₅F₂N₃O₃S

Colore e forma: Neat

Peso molecolare: 367.37

Ref: 86-MM0099.03

Pantoprazole Sulfide

CAS: 102625-64-9

Pantoprazole sulfide, a metabolite of pantoprazole, is formed by CYP2C19 and CYP3A4 enzymes.

Formula: C₁₆H₁₅F₂N₃O₃S

Colore e forma: Solid

Peso molecolare: 367.37

Ref: TM-T37247

Pantoprazole EP Impurity B-d6 (Pantoprazole USP Related Compound B-d6, Pantoprazole Sulfide-d6)

CAS: 102625-64-9

Formula: C₁₆H₉D₆F₂N₃O₃S

Peso molecolare: 373.41

Ref: 4Z-P-0185

5-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole

CAS: 102625-64-9

Purezza: 95.0%

Peso molecolare: 367.3699951171875

Ref: 10-F049541

Pantoprazole EP Impurity B

CAS: 102625-64-9

Formula: C₁₆H₁₅F₂N₃O₃S

Peso molecolare: 367.37

Ref: ST-EA-CP-P15002

Pantoprazole Sulfide

CAS: 102625-64-9

Impurity Pantoprazole EP Impurity B/ Pantoprazole USP Related Compound B Applications Pantoprazole Sulfide (Pantoprazole EP Impurity B) is a metabolite of Pantoprazole (P183000), an antiulcerative, gastric pump inhibitor.

Formula: C₁₆H₁₅F₂N₃O₃S

Colore e forma: Neat

Peso molecolare: 367.37

Ref: TR-P183020

Pantoprazole sulphide

CAS: 102625-64-9

Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.

Formula: C₁₆H₁₅F₂N₃O₃S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 367.37 g/mol

Ref: 3D-ID57911