CAS 104146-53-4

Acido 5-tia-1-azabiciclo[4.2.0]ott-2-ene-2-carbossilico, 7-[[(2Z)-2-(2-ammino-4-tiazolil)-2-(metossimino)acetil]ammino]-3-[(1Z)-2-(4-metil-5-tiazolil)etenil]-8-osso-, sale di sodio (1:1), (6R,7R)-

Descrizione:

Acido 5-tia-1-azabiciclo[4.2.0]ott-2-ene-2-carbossilico, 7-[[(2Z)-2-(2-ammino-4-tiazolil)-2-(metossimino)acetil]ammino]-3-[(1Z)-2-(4-metil-5-tiazolil)etenil]-8-osso-, sale di sodio (1:1), (6R,7R)- è un composto chimico complesso caratterizzato dalla sua struttura biciclica, che include sia moieties di tiazolo che di tiazolidina. Questo composto è notevole per le sue potenziali applicazioni farmacologiche, in particolare come antibiotico, a causa della sua somiglianza strutturale con altri agenti antimicrobici noti. La presenza di più gruppi funzionali, inclusi acidi carbossilici e funzionalità amminiche, contribuisce alla sua reattività e solubilità in ambienti acquosi. La forma di sale sodico migliora la sua stabilità e biodisponibilità. La sua estereoquimica, indicata dalla configurazione (6R,7R), è cruciale per la sua attività biologica, influenzando il modo in cui interagisce con enzimi o recettori target. In generale, questo composto esemplifica l'intricata relazione tra struttura molecolare e funzione biologica, rendendolo un argomento di interesse nella chimica medicinale e nello sviluppo di farmaci.

Formula: C₁₉H₁₈N₆O₅S₃·Na

InChI: InChI=1S/C19H18N6O5S3.Na/c1-8-11(33-7-21-8)4-3-9-5-31-17-13(16(27)25(17)14(9)18(28)29)23-15(26)12(24-30-2)10-6-32-19(20)22-10;/h3-4,6-7,13,17H,5H2,1-2H3,(H2,20,22)(H,23,26)(H,28,29);/b4-3-,24-12-;/t13-,17-;/m1./s1

InChI key: InChIKey=YZHABJAZXAOLGE-WSWQWPGSSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1/C=C\C4=C(C)N=CS4)[H].[Na]

Sinonimi:

• 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(2-(4-methyl-5-thiazolyl)ethenyl)-8-oxo-, monosodium salt, (6R-(3(Z),6-alpha,7-beta(Z)))-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, monosodium salt, [6R-[3(Z),6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, monosodium salt, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, sodium salt (1:1), (6R,7R)-
• 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2E)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-3-[(E)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, sodium salt, (6R,7R)- (1:1)
• Cefditoren sodium
• Me 1206

Cefditoren sodium

CAS: 104146-53-4

Formula: C₁₉H₁₇N₆NaO₅S₃

Peso molecolare: 528.5602

Ref: IN-DA003OQC

Cefditoren Sodium Salt

CAS: 104146-53-4

Formula: C₁₉H₁₇N₆O₅S₃·Na

Colore e forma: Yellow Solid

Peso molecolare: 505.56 22.99

Ref: 4Z-C-761

Cefditoren sodium

CAS: 104146-53-4

Cefditoren sodium: cephalosporin antibiotic for bacterial infections; alters Mrp2, Bcrp, Oat2, P-gp, Oct1 mRNA levels.

Formula: C₁₉H₁₈N₆NaO₅S₃

Colore e forma: Solid

Peso molecolare: 529.57

Ref: TM-T1405L

Cefditoren sodium salt

CAS: 104146-53-4

Formula: C₁₉H₁₇N₆NaO₅S₃

Peso molecolare: 528.56

Ref: 7W-GA4627

Cefditoren acid sodium

CAS: 104146-53-4

Cefditoren acid sodium is an antibacterial agent that belongs to the class of third-generation cephalosporins, which is derived from Acremonium fungus and produced through chemical synthesis. This compound acts by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It achieves this by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. The interruption of peptidoglycan synthesis in the cell wall is crucial for maintaining bacterial cell integrity, and its inhibition results in the bactericidal activity of cefditoren acid sodium. It is effective against a range of Gram-positive and Gram-negative bacteria. The key applications of this compound include the treatment of bacterial infections such as respiratory tract infections, skin infections, and other conditions caused by susceptible bacteria. Its spectrum of activity and pharmacokinetic properties make it suitable for situations where third-generation cephalosporins are indicated. Understanding the specific interaction with PBPs and the resistance mechanisms is crucial for optimizing its clinical use and managing antibiotic resistance.

Formula: C₁₉H₁₇N₆NaO₅S₃

Purezza: 94%Min

Peso molecolare: 528.56 g/mol

Ref: 3D-AC19853