
CAS 1045792-66-2
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4 prodotti.
CAY10603
CAS:CAY10603 (BML-281) is a potent and selective inhibitor of HDAC6.Formula:C22H30N4O6Purezza:95.75% - 98.1%Colore e forma:SolidPeso molecolare:446.5Ref: TM-T1983
1mg59,00€2mg78,00€5mg90,00€10mg161,00€25mg290,00€50mg492,00€100mg710,00€1mL*10mM (DMSO)90,00€Histone deacetylase inhibitor VIII
CAS:Potent and selective inhibitor of histone deacetylase 6 (HDAC6) with IC50 of 2.4 nM. Its anti-inflammatory activity was examined in a mouse model for acute colitis. The compound protected from intestinal inflammation by prevention of infiltration of CD19+ B-cells into the lamina propria of colonic epithelium and attenuated neutrophil activation. Its broad anti-inflammatory response involved decrease in 24 inflammatory chemokines and cytokines. Also, it is a potent inhibitor of cell proliferation in pancreatic cancer cell lines.
Formula:C22H30N4O6Purezza:Min. 95%Colore e forma:White To Off-White SolidPeso molecolare:446.21653



