CAS 104594-70-9

Estere fenetilico dell'acido caffeico

Descrizione:

Estere fenetilico dell'acido caffeico (CAPE) è un composto fenolico derivato dall'acido caffeico, noto per le sue potenziali proprietà antiossidanti, antinfiammatorie e anticancro. È un solido di colore marrone-giallastro a temperatura ambiente ed è solubile in solventi organici come etanolo e dimetilsolfossido, ma ha una solubilità limitata in acqua. Il CAPE presenta una formula molecolare che riflette la sua struttura, che include un gruppo fenetile attaccato allo scheletro dell'acido caffeico. Questo composto è spesso studiato per le sue attività biologiche, inclusa la sua capacità di inibire vari enzimi e modulare le vie di segnalazione, rendendolo di interesse nella ricerca farmacologica. Il CAPE è stato indagato per i suoi effetti protettivi contro lo stress ossidativo e il suo potenziale ruolo nella prevenzione delle malattie croniche. Inoltre, è riconosciuto per la sua capacità di interagire con componenti cellulari, influenzando processi come apoptosi e proliferazione cellulare. In generale, Estere fenetilico dell'acido caffeico è un composto significativo nel campo dei prodotti naturali e della chimica medicinale, con ricerche in corso sulle sue applicazioni terapeutiche.

Formula: C₁₇H₁₆O₄

InChI: InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2

InChI key: InChIKey=SWUARLUWKZWEBQ-UHFFFAOYSA-N

SMILES: C(=CC(OCCC1=CC=CC=C1)=O)C2=CC(O)=C(O)C=C2

Sinonimi:

• 2-Phenylethyl 3-(3,4-Dihydroxyphenyl)-2-Propenoate
• 2-Phenylethyl 3-(3,4-Dihydroxyphenyl)Prop-2-Enoate
• 2-Phenylethyl caffeate
• 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 2-phenylethyl ester
• 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
• Caffeic acid phenethylester
• Phenethyl Caffeate
• β-Phenylethyl caffeate
• Caffeic acid phenethyl ester
• CAPE

Phenethyl Caffeate

CAS: 104594-70-9

Formula: C₁₇H₁₆O₄

Purezza: >98.0%(HPLC)

Colore e forma: White to Orange to Green powder to crystal

Peso molecolare: 284.31

Ref: 3B-P2088

Phenylethyl 3,4-dihydroxycinnamate, 98+%

CAS: 104594-70-9

Inhibitor of protein tyrosine kinase, and is cytotoxic to cancer cell lines

Formula: C₁₇H₁₆O₄

Purezza: 98+%

Peso molecolare: 284.31

Ref: 02-J61386

Caffeic acid-phenethyl ester

CAS: 104594-70-9

CAPE is known to have antimitogenic, anticarcinogenic, antiinflammatory, and immunomodulating properties. The molecular basis for these properties seems to be its ability to specifically and potently inhibit the activation of the nuclear transcription factor NF-kappaB.

Formula: C₁₇H₁₆O₄

Purezza: 99.4%

Colore e forma: White Powder

Peso molecolare: 284.31

Ref: 01-4027526

2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate

CAS: 104594-70-9

Formula: C₁₇H₁₆O₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 284.3065

Ref: IN-DA00HADG

Caffeic acid phenethyl ester

CAS: 104594-70-9

Formula: C₁₇H₁₆O₄

Purezza: ≥ 98.0%

Colore e forma: White to yellow crystalline powder

Peso molecolare: 284.31

Ref: 7W-GK2776

Caffeic Acid Phenethyl Ester

CAS: 104594-70-9

Caffeic Acid Phenethyl Ester

Purezza: ≥98%

Peso molecolare: 284.31g/mol

Ref: 54-BUP17813

Caffeic acid-phenylethyl ester

CAS: 104594-70-9

Formula: C₁₇H₁₆O₄

Colore e forma: Neat

Peso molecolare: 284.31

Ref: 04-C10934730

Caffeic acid phenethyl ester

CAS: 104594-70-9

Formula: C₁₇H₁₆O₄

Purezza: 95%~99%

Peso molecolare: 284.311

Ref: BP-SBP03991

Caffeic Acid Phenethyl Ester

CAS: 104594-70-9

CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.

Formula: C₁₇H₁₆O₄

Purezza: 99.18% - 99.35%

Colore e forma: Less Transparent Liquid Colorless Transparent Liquid

Peso molecolare: 284.31

Ref: TM-T6429

Caffeic acid phenethyl ester

CAS: 104594-70-9

Caffeic acid phenethyl ester

Formula: C₁₇H₁₆O₄

Purezza: 98% (nmr) (Typical Value in Batch COA)

Colore e forma: off-white solid

Peso molecolare: 284.31g/mol

Ref: 54-BIB6022

Caffeic Acid Phenethyl Ester

CAS: 104594-70-9

Applications Cytotoxic agent against cancer cell lines. Inhibitor of ornithine decarboxylase and protein tyrosine kinase. Found to be a specific inhibitor of the nuclear transcription factor, NF-kB. It has also been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation.
References Grunberger, D., et al.: Experientia, 44, 230 (1988), Fesen, M.R., et al.: Biochem. Pharmacol., 48, 595 (1994), Su, Z.Z., et al.: Cancer Res., 54, 1865 (1994), Zheng, Z.S., et al.: Oncol. Res., 7, 445 (1995), Mirzoeva, O.K. and Calder, P.C.: Essent. Fatty Acids, 55, 441 (1996)

Formula: C₁₇H₁₆O₄

Colore e forma: Neat

Peso molecolare: 284.31

Ref: TR-C080050

Caffeic acid phenethyl ester

CAS: 104594-70-9

Caffeic acid phenethyl ester (CAPE) is an active phenolic compound found in honeybee propolis that has the potential to downregulate inflammation in mammals. Studies demonstrated that CAPE specifically inhibits the protein complex NF-κB - a key player in inflammation, associated with the pathogenesis of chronic inflammatory diseases. Moreover, CAPE inhibits the activity of the enzyme cyclooxygenase and the production of nitric oxide by macrophages, also responsible for inflammation. By acting on T cells, CAPE can reduce the production of pro-inflammatory cytokines and increase the production of anti-inflammatory ones, leading to a less overwhelming immune response to allergens.

Formula: C₁₇H₁₆O₄

Purezza: Min. 98.0 Area-%

Peso molecolare: 284.31 g/mol

Ref: 3D-C-1400

PHENETHYL CAFFEATE

CAS: 104594-70-9

Purezza: 97%

Peso molecolare: 284.3110046

Ref: 10-F814395

Phenethyl 3-(3,4-dihydroxyphenyl)acrylate

CAS: 104594-70-9

Formula: C₁₇H₁₆O₄

Purezza: 95.0%

Colore e forma: No data available.

Peso molecolare: 284.311

Ref: 10-F212797