CAS 1049743-58-9

PS 1145 dihydrochloride

CAS: 1049743-58-9

IκB kinase (IKK) inhibitor

Formula: C₁₇H₁₃Cl₃N₄O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 395.67

Ref: TM-T23191

Ps-1145 dihydrochloride

CAS: 1049743-58-9

PS-1145 dihydrochloride is a synthetic chemical compound that acts as a selective inhibitor of the enzyme IκB kinase β (IKK-β). This compound is typically derived through complex chemical synthesis techniques in laboratory environments. PS-1145 targets the NF-κB signaling pathway by directly binding to IKK-β, thereby inhibiting its activity. This inhibition prevents the phosphorylation and subsequent degradation of IκB proteins, which in turn retains NF-κB in the cytoplasm and prevents its transcriptional activity in the nucleus.

Formula: C₁₇H₁₃Cl₃N₄O

Purezza: Min. 95%

Peso molecolare: 395.7 g/mol

Ref: 3D-ZRB74358