CAS 105826-92-4

cloridrato di tropisetron

Descrizione:

cloridrato di tropisetron è un composto chimico utilizzato principalmente come antiemetico, in particolare nella prevenzione della nausea e del vomito associati alla chemioterapia e alla chirurgia. Appartiene alla classe degli antagonisti del recettore della serotonina 5-HT3, che funzionano bloccando l'azione della serotonina su questi recettori nel sistema nervoso centrale e nel tratto gastrointestinale. Questa azione aiuta a mitigare le sensazioni di nausea e vomito. Il composto è tipicamente presentato come una polvere cristallina bianca o bianco sporco, solubile in acqua e metanolo, il che facilita la sua formulazione in varie preparazioni farmaceutiche. La sua struttura molecolare include un anello di piperidina, contribuendo alla sua attività farmacologica. cloridrato di tropisetron viene somministrato per via orale o endovenosa, a seconda dello scenario clinico, ed è generalmente ben tollerato, sebbene gli effetti collaterali possano includere mal di testa, costipazione o vertigini. Come per qualsiasi farmaco, è essenziale utilizzarlo sotto supervisione medica per garantire sicurezza ed efficacia.

Formula: C₁₇H₂₀N₂O₂·ClH

InChI: InChI=1/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,18H,6-9H2,1H3;1H/t11-,12+,13+;

InChI key: InChIKey=XIEGSJAEZIGKSA-LUNMCBQDNA-N

SMILES: C(O[C@H]1C[C@@]2(N(C)[C@](C1)(CC2)[H])[H])(=O)C=3C=4C(NC3)=CC=CC4.Cl

Sinonimi:

• (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate hydrochloride (1:1)
• 1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride (1:1)
• 1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, monohydrochloride
• 1H-Indole-3-carboxylic acid, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, monohydrochloride, endo-
• 8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate hydrochloride (1:1)
• Novaban
• Sdz-Ics 930
• Tropiserton Hydrochloride
• Tropisetron HCl
• 3-TROPANYLINDOLE-3-CARBOXYLATE HYDROCHLORIDE
• 3-Tropanylindole-3-carboxylate monohydrochloride, ICS-205,930, Navoban, 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester monohydrochloride
• Tropisetron monohydrochloride
• TROPISETRON HYDROCHLORIDE
• TROPISETRON HYDROCHLORIDE 98.5-101.5%
• 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrochloride
• (3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-INDOLE-3-CARBOXYLIC ACID ESTER MONOHYDROCHLORIDE

3-Tropanylindole-3-carboxylate hydrochloride

CAS: 105826-92-4

A selective 5-HT3 serotonin receptor antagonist

Formula: C₁₇H₂₀N₂O₂•HCl

Peso molecolare: 320.82

Ref: 02-J62807

Tropisetron Hydrochloride

CAS: 105826-92-4

Colore e forma: Neat

Ref: 61-FOR0763.00

TROPISETRON HYDROCHLORIDE CRS

CAS: 105826-92-4

TROPISETRON HYDROCHLORIDE CRS

Formula: C₁₇H₂₀N₂O₂

Colore e forma: White. Powder.

Peso molecolare: 284.3529

Ref: 41-Y0000616

(1R,3R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride

CAS: 105826-92-4

Formula: C₁₇H₂₁ClN₂O₂

Purezza: %

Colore e forma: Solid

Peso molecolare: 320.8138

Ref: IN-DA003V99

Tropisetron hydrochloride

CAS: 105826-92-4

Tropisetron hydrochloride (Tropisetron HCl) is a selective, competitive serotonin 5-HT3 receptor antagonist, with antinauseant and antiemetic activities.

Formula: C₁₇H₂₁ClN₂O₂

Purezza: 99.72% - 99.83%

Colore e forma: Solid

Peso molecolare: 320.82

Ref: TM-T1173

Tropisetron hydrochloride

CAS: 105826-92-4

Formula: C₁₇H₂₀N₂O₂HCl

Peso molecolare: 320.82

Ref: 7W-GP5100

Endo-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-yl 1H-Indole-3-Carboxylate Hydrochloride

CAS: 105826-92-4

Endo-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-yl 1H-Indole-3-Carboxylate Hydrochloride

Purezza: 98%

Peso molecolare: 320.81g/mol

Ref: 54-OR1013106

Tropisetron hydrochloride

CAS: 105826-92-4

Tropisetron hydrochloride

Purezza: ≥98%

Peso molecolare: 320.82g/mol

Ref: 54-BUP13722

Tropisetron HCl

CAS: 105826-92-4

Formula: C₁₇H₂₀N₂O₂·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 284.36 36.46

Ref: 4Z-T-124005

Tropisetron Hydrochloride

Prodotto controllato

CAS: 105826-92-4

Formula: C₁₇H₂₀N₂O₂·ClH

Colore e forma: Neat

Peso molecolare: 320.81

Ref: 86-MM0763.00

Tropisetron Hydrochloride

CAS: 105826-92-4, 89565-68-4

Formula: C₁₇H₂₀N₂O₂·HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 320.82

Ref: 3B-T2743

Tropisetron-d5

Prodotto controllato

CAS: 105826-92-4

Applications Tropisetron-d5, is the labeled analogue of Tropisetron Hydrochloride (T892700), which is specific serotonin (5-HT3) receptor antagonist. It is also an antiemetic.
References Richardson, B.P., et al.: Nature, 316, 126 (1985), Williams, F.M., et al.: J. Cardiovasc. Pharmacol., 7, 550 (1985), Waeber, C., et al.: Neuroscience, 31, 393 (1989), Seynaeve, C., et al.: Anti-Cancer Drugs, 2, 343 (1991), Fischer, V., et al.: Dug Metab. Dispos., 20, 603 (1992),

Formula: C₁₇H₁₅D₅N₂O₂

Colore e forma: Neat

Peso molecolare: 289.38

Ref: TR-T892702

Tropisetron hydrochloride

CAS: 105826-92-4

Purezza: ≥98%

Peso molecolare: 320.8200073

Ref: 10-F862915

Tropisetron Hydrochloride

Prodotto controllato

CAS: 105826-92-4

Stability Hygroscopic
Applications Specific serotonin (5-HT3) receptor antagonist. Antiemetic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Richardson, B.P., et al.: Nature, 316, 126 (1985), Williams, F.M., et al.: J. Cardiovasc. Pharmacol., 7, 550 (1985), Waeber, C., et al.: Neuroscience, 31, 393 (1989), Seynaeve, C., et al.: Anti-Cancer Drugs, 2, 343 (1991), Fischer, V., et al.: Dug Metab. Dispos., 20, 603 (1992),

Formula: C₁₇H₂₀N₂O₂·ClH

Colore e forma: White

Peso molecolare: 320.81

Ref: TR-T892700

Tropisetron Hydrochloride

CAS: 105826-92-4

Formula: C₁₇H₂₀N₂O₂HCl

Peso molecolare: 284.36 : 36.46

Ref: ST-EA-CP-T194001

Tropisetron hydrochloride

CAS: 105826-92-4

5-HT3 receptor antagonist; alpha-7 nicotinic acetylcholine receptor partial agonist

Formula: C₁₇H₂₀N₂O₂•HCl

Purezza: Min. 95%

Peso molecolare: 320.81 g/mol

Ref: 3D-FT28617