![Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl N…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F382836-5-o-44-dimethoxytrityl-5-methyl-n4-benzoyl-2-deoxycytidine-3-2-cyanoethyl-n-n-diisopropyl-phosphoramidite.webp&w=3840&q=75)
CAS 105931-57-5
:Citosina, N-benzoyl-5′-O-[bis(4-metossifenil)fenilmetil]-2′-desossi-5-metil-, 3′-[2-cianoetile N,N-bis(1-metiletil)fosforamidite]
Descrizione:
Citosina, N-benzoyl-5′-O-[bis(4-metossifenil)fenilmetil]-2′-desossi-5-metil-, 3′-[2-cianoetile N,N-bis(1-metiletil)fosforamidite] è un composto chimico complesso utilizzato principalmente nel campo della chimica degli acidi nucleici, in particolare nella sintesi di oligonucleotidi. Questa sostanza presenta una base di citidina, che è un nucleoside composto da un anello di pirimidina e uno zucchero ribosio, modificato con un gruppo benzilico e una porzione di fosforamidite. La presenza del gruppo bis(4-metossifenile)fenilmetile migliora la sua stabilità e solubilità, rendendolo adatto per varie applicazioni biochimiche. La funzionalità di fosforamidite cianoetilica consente reazioni di accoppiamento efficienti durante la sintesi di oligonucleotidi, facilitando la formazione di legami fosfodiestere. Questo composto è caratterizzato dalla sua capacità di partecipare a reazioni selettive, contribuendo allo sviluppo di metodologie sintetiche in biologia molecolare e ingegneria genetica. Il suo numero CAS, 105931-57-5, funge da identificatore unico per scopi normativi e di ricerca.
Formula:C47H54N5O9P
InChI:InChI=1S/C47H54N5O8P/c1-32(2)52(33(3)4)61(58-28-14-27-48)60-41-29-43(51-30-34(5)44(50-46(51)54)49-45(53)35-15-10-8-11-16-35)59-42(41)31-57-47(36-17-12-9-13-18-36,37-19-23-39(55-6)24-20-37)38-21-25-40(56-7)26-22-38/h8-13,15-26,30,32-33,41-43H,14,28-29,31H2,1-7H3,(H,49,50,53,54)/t41-,42+,43+,61?/m0/s1
InChI key:InChIKey=AGMUHEZFYUECLW-QUZMAVINSA-N
SMILES:C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@@H](O1)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C(C)=C2)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6
Sinonimi:- 4: PN: US20030212017 PAGE: 17 claimed DNA
- 5'-O-(4,4'-Dimethoxytrityl)-5-Methyl-N4-Benzoyl-2'-Deoxycytidine-3'-(2-Cyanoethyl-N,N-Diisopropyl)Phosphoramidite
- 5: PN: US20030211606 PAGE: 17 claimed DNA
- 6: PN: US20040014048 PAGE: 18 claimed DNA
- 6: PN: US20040014049 PAGE: 18 claimed DNA
- 7: PN: US20030198965 PAGE: 17 claimed DNA
- 7: PN: US20040014047 PAGE: 18 claimed DNA
- 80: PN: US20040005707 PAGE: 18 claimed DNA
- 8: PN: US20040005565 PAGE: 17-22 claimed DNA
- 8: PN: US20040005569 PAGE: 20 claimed DNA
- 8: PN: US20040005570 PAGE: 18 claimed DNA
- 8: PN: US20040006029 PAGE: 20 claimed DNA
- 8: PN: US20040006030 PAGE: 20 claimed DNA
- 8: PN: US20040014050 PAGE: 18 claimed DNA
- 8: PN: US20040014051 PAGE: 20 claimed DNA
- 8: PN: US20040014699 PAGE: 18 claimed DNA
- 8: PN: WO03106645 PAGE: 64 claimed DNA
- Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-5-methyl-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
- N4-Benzoyl-5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-cyanoethyl Phosphoramidite
- DMTr-5-Me-dC(Bz)-3'-CE-Phosphoramidite
- 5'-O-DMT-N4-Benzoyl-2'-Deoxy-5-Methylcytidine-CE Phosphoramidite
- 5-Me-DMT-dC(Bz)-CE
- N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-deoxycytidine-3'-cyanoethyl Phosphoramidite
- N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE Phosphoramidite
- 8: PN: US20040014050 PAGE
- 5-methyldeoxycytidine-ce*phosphoramidite for cycl
- 5'-O-DMT-N4-Benzoyl-5-methyl-2'-deoxycytidine 3'-CE phosphoramidite
- US20040006030 PAGE: 20 claimed DNA
- 5'-Dimethoxytrityl-N-benzoyl-5-methyl-2'-deoxyCytidine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- 5-Me-dCBzPhosphoramidite
- deoxy N-Bz 5-Me Cytidine Amidite
- 2'-deoxycytidine-3'-cyanoethyl
- Phosphoramidite
- N-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-tetrahydrofuran-2-yl]-5-methyl-2-oxo-pyrimidin-4-yl]benzamide
- N-blocked-5'-O-DMT CED methyldeoxycytidine phosphoramidite
- 5-Me-DMT-dC(Bz)-CE Phosphoramidite
- N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
- 5'-O-(4,4'-DiMethoxytrityl)-N4-benzoyl-2'-deoxy-5-Methylcytidine-3'- O-(O-2-cyanoethyl-N,N-diisopropylaMino) phosphoraMidite
- N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-cytidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- DMT-5Me-dC(Bz)-CE Phosphoramidite
- N4-benzoyl-5-methyl-5'-O-(4, 4'-dimethoxytrityl)-
- Bz-5-Me-dC phosphoramidite
- 5-Me Bz dC Beta-Cyanoethyl Phosphoramidite (500 mg) (5-Methyl-5'-O-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
- 5-Me-dC CE Phosphoramidite
- Cytidine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-,3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
- N -Benzoyl-5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-cyanoethyl-N,N-diisopropylphosphoramidite(DMT-5-MedC(bz)phosphoramidite)
- Vedi altri sinonimi
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8 prodotti.
5-Me Bz dC β-Cyanoethyl Phosphoramidite (5-Methyl-5'-O-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-O-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C47H54N5O8PColore e forma:White PowderPeso molecolare:847.3715'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
CAS:Formula:C47H54N5O8PPurezza:98%Colore e forma:SolidPeso molecolare:847.9341DMT-5Me-dC(Bz)-CE Phosphoramidite
CAS:DMT-5Me-dC(Bz)-CE PhosphoramiditePurezza:99%Peso molecolare:847.93g/molDMT-5Me-dC(Bz)-CE Phosphoramidite
CAS:DMT-5Me-dC(Bz)-CE Phosphoramidite aids in crafting LNAs for better fluorescent probes.Formula:C47H54N5O8PColore e forma:SolidPeso molecolare:847.93DMT-5-Me-dC(Bz) Phosphoramidite
CAS:Formula:C47H54N5O8PPurezza:>95.0%(HPLC)Colore e forma:White to Yellow powder to crystalPeso molecolare:847.95N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
CAS:<p>Nucleoside phosphoramidites are widely used as building blocks in the chemical synthesis of oligonucleotides. The use of a chemical synthesis rather than an enzymatic one allows bespoke oligonucleotides of a desired sequence to be obtained. 3’-Cyanoethyl phosphoramidites are typically modified by reaction with the 5’ hydroxyl of the next nucleoside in the desired sequence. The reaction is usually catalysed by 1H-tetrazole or 4,5-dicyanoimidazole in acetonitrile. N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite, also called N4-Bz-5'-DMT-5-Me-dC phosphoramidite, is used in the synthesis of 2’-deoxy-5-methylcytidine-containing oligonucleotides as antisense drugs.</p>Formula:C47H54N5O8PPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:847.93 g/mol
