CAS 106477-83-2

Pancreastatina (1-49) (suino)

Descrizione:

Pancreastatina (1-49) (suino) è un peptide derivato dal gene proglucagone, prodotto principalmente nel pancreas dei maiali. È composto da 49 aminoacidi ed è noto per il suo ruolo nella regolazione di vari processi fisiologici, in particolare nel metabolismo del glucosio e nella secrezione di insulina. Questo peptide agisce come un inibitore del rilascio di insulina, svolgendo così un ruolo cruciale nel mantenimento dell'omeostasi del glucosio. La pancreastatina influisce anche sulla motilità gastrointestinale ed è stata implicata nella modulazione della secrezione esocrina pancreatica. La sua struttura include una sequenza specifica di aminoacidi che contribuiscono alla sua attività biologica, ed è spesso studiata per le sue potenziali applicazioni terapeutiche nel diabete e nei disturbi metabolici correlati. Il numero CAS 106477-83-2 identifica in modo univoco questa sostanza nei database chimici, facilitando la ricerca e i processi normativi. In generale, la pancreastatina (1-49) è significativa sia nella ricerca fisiologica che nelle potenziali applicazioni cliniche, in particolare nella comprensione e gestione delle malattie metaboliche.

Formula: C₂₁₄H₃₃₀N₆₈O₇₆S

InChI: InChI=1/C214H330N68O76S/c1-101(2)83-136(197(344)272-137(84-112-31-15-14-16-32-112)198(345)258-118(37-23-74-230-212(223)224)179(326)234-91-151(222)290)253-159(298)98-239-180(327)122(45-58-147(218)286)268-202(349)143-41-27-78-279(143)207(354)108(9)246-156(295)92-235-173(320)103(4)249-206(353)171(111(12)285)277-196(343)133(57-70-168(315)316)267-192(339)131(55-68-166(311)312)266-191(338)130(54-67-165(309)310)265-190(337)129(53-66-164(307)308)264-189(336)128(52-65-163(305)306)263-187(334)125(47-60-149(220)288)260-186(333)121(39-25-76-232-214(227)228)259-200(347)141(99-283)275-199(346)138(86-114-90-229-100-242-114)273-193(340)132(56-69-167(313)314)262-185(332)120(38-24-75-231-213(225)226)255-174(321)104(5)244-154(293)93-237-178(325)117(35-19-21-72-215)251-158(297)97-238-181(328)123(49-62-160(299)300)269-204(351)145-43-29-80-281(145)211(358)146-44-30-81-282(146)209(356)135(48-61-150(221)289)271-177(324)106(7)247-183(330)126(50-63-161(301)302)261-188(335)127(51-64-162(303)304)256-175(322)105(6)245-155(294)95-241-205(352)170(110(11)284)276-195(342)119(36-20-22-73-216)252-157(296)96-236-172(319)102(3)243-153(292)94-240-182(329)139(87-169(317)318)274-194(341)134(71-82-359-13)257-176(323)107(8)248-201(348)142-40-26-77-278(142)208(355)109(10)250-184(331)124(46-59-148(219)287)270-203(350)144-42-28-79-280(144)210(357)140(254-152(291)88-217)85-113-89-233-116-34-18-17-33-115(113)116/h14-18,31-34,89-90,100-111,117-146,170-171,233,283-285H,19-30,35-88,91-99,215-217H2,1-13H3,(H2,218,286)(H2,219,287)(H2,220,288)(H2,221,289)(H2,222,290)(H,229,242)(H,234,326)(H,235,320)(H,236,319)(H,237,325)(H,238,328)(H,239,327)(H,240,329)(H,241,352)(H,243,292)(H,244,293)(H,245,294)(H,246,295)(H,247,330)(H,248,348)(H,249,353)(H,250,331)(H,251,297)(H,252,296)(H,253,298)(H,254,291)(H,255,321)(H,256,322)(H,257,323)(H,258,345)(H,259,347)(H,260,333)(H,261,335)(H,262,332)(H,263,334)(H,264,336)(H,265,337)(H,266,338)(H,267,339)(H,268,349)(H,269,351)(H,270,350)(H,271,324)(H,272,344)(H,273,340)(H,274,341)(H,275,346)(H,276,342)(H,277,343)(H,299,300)(H,301,302)(H,303,304)(H,305,306)(H,307,308)(H,309,310)(H,311,312)(H,313,314)(H,315,316)(H,317,318)(H4,223,224,230)(H4,225,226,231)(H4,227,228,232)/t102-,103-,104-,105-,106-,107-,108-,109-,110+,111+,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,170-,171-/m0/s1

Sinonimi:

• H-Gly-Trp-Pro-Gln-Ala-Pro-Ala-Met-Asp-Gly-Ala-Gly-Lys-Thr-Gly-Ala-Glu-Glu-Ala-Gln-Pro-Pro-Glu-Gly-Lys-Gly-Ala-Arg-Glu-His-Ser-Arg-Gln-Glu-Glu-Glu-Glu-Glu-Thr-Ala-Gly-Ala-Pro-Gln-Gly-Leu-Phe-Arg-Gly-NH2
• Pancreastatin, Porcine

Pancreastatin, Porcine

CAS: 106477-83-2

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₂₁₄H₃₃₀N₆₈O₇₆S

Peso molecolare: 5,103.4 g/mol

Ref: 3D-PP50130

Pancreastatin (Dephosphorylated Porcine)

CAS: 106477-83-2

Pancreatastatin is a peptide hormone that inhibits energy metabolism. Pancreatastatin is a biologically active peptide that has been isolated from the pancreas and shown to have effects on the endocrine system, including regulation of feeding behavior. Pancreatastatin is also known as somatostatin and is found in both animals and humans. Pancreatastatin has been shown to inhibit cellular proliferation and decrease tumor size in animal models of cancer, as well as to regulate blood sugar levels in diabetic patients. Pancreatastatin is also used for treating bowel diseases such as colitis.

Formula: C₂₁₄H₃₃₀N₆₈O₇₆S

Purezza: Min. 95%

Peso molecolare: 5,103.49 g/mol

Ref: 3D-PAN-3978-PI

Pancreastatin (dephosphorylated) (porcine) trifluoroacetate salt

CAS: 106477-83-2

Pancreastatin is a cytosolic protein that inhibits the production of peptide hormones such as glucagon, insulin, and gastrin. It is used to treat bowel disease, including carcinoid syndrome and inflammatory bowel disease. Pancreastatin has been shown to inhibit the activity of cyclase enzymes that are responsible for the production of these hormones. Pancreatic beta-cells produce pancreatic polypeptide (PP), which is converted by pancreastatin into inactive PP2. Pancreatic alpha-cells produce somatostatin (SS), which is converted by pancreastatin into inactive SS2. Pancreatic delta cells produce pancreatic polypeptide (PP), which is not affected by pancreastatin. Pancreatic somatostatinomas secrete SS, which is not affected by pancreastatin.

Formula: C₂₁₄H₃₃₀N₆₈O₇₆S

Purezza: Min. 95%

Peso molecolare: 5,103.39 g/mol

Ref: 3D-FP109742