CAS 107444-51-9

peptide simile al glucagone I frammento 7-36*amide umano

Descrizione:

Il frammento 7-36 amide del peptide simile al glucagone-1 (GLP-1) è un ormone peptidico che svolge un ruolo cruciale nel metabolismo del glucosio e nella regolazione dell'appetito. Deriva dal gene proglucagone ed è principalmente secreto dalle cellule L intestinali in risposta all'assunzione di cibo. Questo peptide è composto da 30 aminoacidi ed è noto per la sua capacità di stimolare la secrezione di insulina in modo dipendente dal glucosio, contribuendo così a ridurre i livelli di zucchero nel sangue. Inoltre, il frammento 7-36 amide del GLP-1 inibisce il rilascio di glucagone, rallenta lo svuotamento gastrico e promuove la sazietà, rendendolo un obiettivo per il trattamento del diabete e la gestione dell'obesità. La forma amide indica che il C-terminale del peptide è amidato, il che è importante per la sua attività biologica e stabilità. Grazie ai suoi effetti fisiologici, il GLP-1 e i suoi analoghi sono utilizzati in applicazioni terapeutiche, in particolare nella gestione del diabete mellito di tipo 2. Il numero CAS 107444-51-9 identifica in modo univoco questo specifico peptide nelle banche dati chimiche, facilitando la ricerca e lo sviluppo in farmacologia e biochimica.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Sinonimi:

• Glucagon-Like Peptide 1 (7-36) amide (human)
• H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2
• Glp-1(7-36)
• Glucagon-Like Peptide I Fragment 7-36 Amide Human

Glucagon-Like Peptide-1 (7-36) amide, human

CAS: 107444-51-9

For cellular and molecular biology applications

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Colore e forma: Lyophilized Powder, White

Peso molecolare: 3297.7

Ref: 02-J66197

GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)

CAS: 107444-51-9

GLP-1 (7-36) amide is secreted from the lower small intestine and shows a strong insulinotropic effect. GLP-1 (7-36) amide is considered as the most important incretin hormone. Its action is mediated by receptors expressed by the endocrine pancreatic B-cells. Considerable interest has focused on the development of this peptide as a therapeutic strategy for non-insulin-dependent (type 2 ) diabetes mellitus and associated neuropathy.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purezza: > 96%

Colore e forma: White

Peso molecolare: 3297.68

Ref: 01-4030663

GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

CAS: 107444-51-9

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 3297.6297

Ref: IN-DA008R5L

GLP-1(7-36)

CAS: 107444-51-9

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purezza: 95%~99%

Colore e forma: White to Off-white Powder

Peso molecolare: 3297.63

Ref: BP-BPPG034

GLP-1(7-36), amide

CAS: 107444-51-9

GLP-1 secretion by human enteroendocrine NCI-H716 cells is augmented in a dose-dependent manner by the addition of CPE.Cost-effective and quality-assured.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purezza: 99.85%

Colore e forma: White Powder

Peso molecolare: 3297.63

Ref: TM-T3984

GLP-1 (7-36) amide

CAS: 107444-51-9

This is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of GLP-1 (1-36) amide peptide.  This peptide, human GLP-1 (7–36), shares the same sequence with preproglucagon (78-107), amide, human.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Colore e forma: Powder

Peso molecolare: 3,297.63 g/mol

Ref: 3D-CRB1000250

Glucagon-like Peptide 1 (Human, 7-36 Amide)

CAS: 107444-51-9

Glucagon-like peptide 1 (GLP-1) is a peptide hormone that belongs to the glucagon family. It is a 36 amino acid polypeptide and is naturally synthesized in the ileum of humans, pigs, and cows. GLP-1 is an activator of ion channels, which are protein structures that regulate the flow of ions across cell membranes. This hormone also has been shown to inhibit the activity of protein interactions at the cell membrane or ligand binding to receptors.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purezza: Min. 95%

Peso molecolare: 3,297.6 g/mol

Ref: 3D-PGL-4344-V

Glucagon-Like Peptide I (7-36), amide, human

CAS: 107444-51-9

Custom research peptide; min purity 95%.

Formula: C₁₄₉H₂₂₉N₄₀O₄₅

Purezza: Min. 95%

Peso molecolare: 3,297.7 g/mol

Ref: 3D-PG16978

Glucagon-Like Peptide I (7-36), amide, human

CAS: 107444-51-9

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Peso molecolare: 3,297.7 g/mol

Ref: 3D-PP50623

Glucagon-like peptide 1 (7-36) amide

CAS: 107444-51-9

Glucagon-like peptide 1 (7-36) amide is a peptide hormone produced by the ileum and colon of the small intestine in response to food intake. It stimulates insulin release from the pancreas, inhibits glucagon secretion, and slows gastric emptying. GLP-1 is also a potent regulator of glucose homeostasis. The GLP-1 analogues are used for treatment of type 2 diabetes mellitus. These analogues are either injected or taken orally and mimic the effect of natural GLP-1 on blood sugar regulation and appetite control. The long duration of action means that daily injections or multiple oral doses are required to maintain therapeutic levels.

Formula: C₁₄₉H₂₂₆N₄₀O₄₅

Purezza: Min. 95%

Peso molecolare: 3,297.63 g/mol

Ref: 3D-FG109975