CAS 108050-54-0

tilmicosina

Descrizione:

tilmicosina è un antibiotico macrolide semisintetico utilizzato principalmente in medicina veterinaria, in particolare per il trattamento delle infezioni respiratorie nel bestiame, come bovini e suini. È derivato dalla fermentazione del batterio *Streptomyces fradiae*. tilmicosina mostra un ampio spettro di attività contro vari batteri Gram-positivi e alcuni batteri Gram-negativi, rendendolo efficace nel combattere le infezioni causate da patogeni come *Mycoplasma* e *Pasteurella*. Il composto agisce inibendo la sintesi proteica batterica, impedendo così la crescita e la riproduzione dei batteri. tilmicosina viene tipicamente somministrato per iniezione o in formulazioni alimentari, ed è noto per la sua lunga emivita, che consente una somministrazione meno frequente. Tuttavia, è importante notare che tilmicosina può essere tossico per alcune specie animali, in particolare cavalli e umani, portando a potenziali preoccupazioni per la sicurezza. Come per tutti gli antibiotici, l'uso di tilmicosina deve essere gestito con attenzione per prevenire lo sviluppo di resistenza agli antibiotici.

Formula: C₄₆H₈₀N₂O₁₃

InChI: InChI=1/C46H80N2O13/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3/b15-14+,25-19+/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-/m1/s1

InChI key: InChIKey=JTSDBFGMPLKDCD-XVFHVFLVSA-N

SMILES: O([C@H]1[C@@H](CCN2C[C@@H](C)C[C@@H](C)C2)C[C@@H](C)C(=O)/C=C/C(/C)=C/[C@H](CO[C@H]3[C@H](OC)[C@H](OC)[C@H](O)[C@@H](C)O3)[C@@H](CC)OC(=O)C[C@@H](O)[C@@H]1C)[C@H]4[C@H](O)[C@@H](N(C)C)[C@H](O)[C@@H](C)O4

Sinonimi:

• 20-Deoxo-20-(3,5-Dimethyl-1-Piperidinyl)Desmycosin
• 4^A-O-De(2,6-dideoxy-3-C-methyl-α-<span class="text-smallcaps">L</span>-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin
• 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin
• Antibiotic EL 870
• El 870
• Ly 177370
• Micotil
• Micotil 300
• Oxacyclohexadecane, tylosin deriv.
• Provitil
• Pulmotil
• Tilmicosin, Vetranal
• Tilmicosin  base
• Tylmicosine
• Tylosin, 4^A-O-de(2,6-dideoxy-3-C-methyl-α-<span class="text-smallcaps">L</span>-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]-
• Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-.alpha.-L-ribo-hexopyranosyl)-20-deoxo-20-(3R,5S)-3,5-dimethyl-1-piperidinyl-
• [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-3-(dimethylamino)-beta-D-glucopyranosyl]oxy}-11-{2-[(3R,5S)-3,5-dimethylpiperidin-1-yl]ethyl}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxooxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside
• cis-Tilmicosin
• Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]-
• (11Z,13Z)-6-{[4-(diMethylaMino)-3,5-dihydroxy-6-Methyloxan-2-yl]oxy}-7-[2-(3,5-diMethylpiperidin-1-yl)ethyl]-16-ethyl-4-hydroxy-15-{[(5-hydroxy-3,4-diMethoxy-6-Methyloxan-2-yl)oxy]Methyl}-5,9,13-triMethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione
• 20-Deoxy-20-(3,5-diMethylpiperidin-1-yl)-desMycosin, EL-870
• 20%Tilmicosin
• Tilmicosin,20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin
• TILMICOSIN
• 4'-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-(3,5-dimethyl-1-piperidinyl)tyrosine [antibiotic]
• Tilmicosine
• Tilmicosin (250 mg)

Tilmicosin

CAS: 108050-54-0

Antibiotics nesoi

Formula: C₄₆H₈₀N₂O₁₃

Colore e forma: White Off-White Powder

Peso molecolare: 868.56604

Ref: 45-1667370

Tilmicosin

CAS: 108050-54-0

Tilmicosin (EL-870), a macrolide antibiotic, treats bovine and ovine respiratory diseases in animals.

Formula: C₄₆H₈₀N₂O₁₃

Purezza: 97.84% - 99.5%

Colore e forma: Solid

Peso molecolare: 869.13

Ref: TM-T0777

Tilmicosin

CAS: 108050-54-0

Formula: C₄₆H₈₀N₂O₁₃

Purezza: ≥ 85.0% (anhydrous basis)

Colore e forma: White to off-white powder

Peso molecolare: 869.13

Ref: 7W-GP6895

Tilmicosin, 10mM (in DMSO)

CAS: 108050-54-0

Tilmicosin, 10mM (in DMSO)

Purezza: ≥95%

Peso molecolare: 869.13g/mol

Ref: 54-BUP19943

Tilmicosin

CAS: 108050-54-0

Tilmicosin

Purezza: ≥98%

Peso molecolare: 869.13g/mol

Ref: 54-BUP18452

Tilmicosin 100 µg/mL in Acetonitrile

CAS: 108050-54-0

Formula: C₄₆H₈₀N₂O₁₃

Colore e forma: Single Solution

Peso molecolare: 869.13

Ref: 04-A17582000AL-100

Tilmicosin

Prodotto controllato

CAS: 108050-54-0

Formula: C₄₆H₈₀N₂O₁₃

Colore e forma: Neat

Peso molecolare: 869.13

Ref: 04-C17582000

Tilmicosin

CAS: 108050-54-0

Formula: C₄₆H₈₀N₂O₁₃

Colore e forma: White To Off-White Solid

Peso molecolare: 869.15

Ref: 4Z-T-193001

Tilmicosin, 85%

CAS: 108050-54-0

Applications Macrolide antibiotic structurally related to tylosin. Antibacterial.
References Debono, M., et al.: J. Antibiot., 42, 1253 (1989), Ose, E.E., et al.: Vet. Rec., 123, 367 (1988), Morck, D.W., et al.: J. Am. Vet. Med. Assoc., 202, 273 (1993),

Formula: C₄₆H₈₀N₂O₁₃

Purezza: 85%

Colore e forma: White To Off-White

Peso molecolare: 869.13

Ref: TR-T440500

Tilmicosin-d3

Prodotto controllato

CAS: 108050-54-0

Applications Tilmicosin-d3 is the labeled analogue of Tilmicosin (T440500), a macrolide antibiotic structurally related to tylosin. Antibacterial.
References Debono, M., et al.: J. Antibiot., 42, 1253 (1989); Ose, E.E., et al.: Vet. Rec., 123, 367 (1988); Morck, D.W., et al.: J. Am. Vet. Med. Assoc., 202, 273 (1993)

Formula: C₄₆H₇₇D₃N₂O₁₃

Colore e forma: White To Off-White

Peso molecolare: 872.15

Ref: TR-T440502

Tilmicosin - Bio-X ™

CAS: 108050-54-0

Tilmicosin is a macrolide antibiotic that is used in veterinary medicine. It is used to treat bovine respiratory disease and inhibits bacterial growth by binding to the 50S ribosomal subunit of the bacteria resulting in reduced protein synthesis.

Formula: C₄₆H₈₀N₂O₁₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 869.13 g/mol

Ref: 3D-BT166387

Tilmicosin

CAS: 108050-54-0

Tilmicosin is a macrolide antibiotic with action on bacterial protein synthesis inhibition and is used for treating respiratory infections in cattle and sheep.

Formula: C₄₆H₈₀N₂O₁₃

Purezza: Min. 85 Area-%

Colore e forma: White Powder

Peso molecolare: 869.13 g/mol

Ref: 3D-AD31127