CAS 108321-42-2

Solfato di genetecina

Descrizione:

Solfato di genetecina, noto anche come G418, è un antibiotico aminoglicosidico che viene utilizzato principalmente in biologia molecolare per la selezione di cellule geneticamente modificate. È efficace contro un'ampia gamma di batteri ed è particolarmente noto per la sua capacità di inibire la sintesi proteica legandosi alla subunità ribosomiale 30S. Questo composto è spesso utilizzato nella coltura cellulare per selezionare cellule che sono state trasfettate con plasmidi contenenti un marcatore genetico per la resistenza a Geneticin. La forma solfato ne migliora la solubilità in soluzioni acquose, rendendolo adatto per applicazioni di laboratorio. Il Geneticin è tipicamente utilizzato a concentrazioni che variano a seconda del tipo di cellula e delle condizioni sperimentali. È importante maneggiare Solfato di genetecina con cura, poiché può essere tossico per le cellule non resistenti. Inoltre, a causa delle sue proprietà antibiotiche, è fondamentale considerare gli effetti potenziali sulla flora microbica nei set sperimentali. In generale, Solfato di genetecina è uno strumento prezioso nella ingegneria genetica e nella ricerca in biologia cellulare.

Formula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

InChI: InChI=1S/C20H40N4O10.H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;(H2,1,2,3,4)/t6-,7+,8-,9-,10-,11+,12+,13-,14-,15-,16+,17-,18-,19-,20+;/m1./s1

InChI key: InChIKey=QNQZPJLBGRQFDD-ZMSORURPSA-N

SMILES: O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@]([C@@H](C)O)([C@@H](O)[C@H](O)[C@H]2N)[H])[C@@H](N)C[C@H]1N)[C@@H]3[C@H](O)[C@@H](NC)[C@@](C)(O)CO3.S(=O)(=O)(O)O

Sinonimi:

• (2R,3S,4R,5R,6S)-5-amino-6-[(1S,2R,4S,6R)-4,6-diamino-3-[(3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-2-(1-hydroxyethyl)tetrahydropyran-3,4-diol
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2) (salt)
• ANTIBIOTIC G-418 Sulfate
• G-418 Sulfate
• G-418 Sulphate
• G418 Disulfate Cell Culture Tested
• G418 Disulfate Plant Cell Culture Tested
• G418 Solution
• G418 Sulfate
• Geneticin sulfate
• Sulfuric Acid
• D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)

G418 disulfate, Cell Culture Reagent

CAS: 108321-42-2

G418 disulfate, cell culture reagent, 108321-42-2, is an aminoglycoside antibiotic structurally related to gentamicin B1. Learn more at Thermo Fisher Scientific.

Formula: C₂₀H₄₄N₄O₁₈S₂

Colore e forma: White, Powder

Peso molecolare: 692.70

Ref: 02-J62671

G418 disulfate, 50mg/ml solution

CAS: 108321-42-2

G418 disulfate, 108321-42-2, is an aminoglycoside antibiotic structurally related to gentamicin B1 suitable for cell culture. Learn more at Thermo Fisher Scientific.

Formula: C₂₀H₄₄N₄O₁₈S₂

Colore e forma: Liquid, Clear colorless

Peso molecolare: 692.70

Ref: 02-J63871

G 418 Disulfate Salt

CAS: 108321-42-2

Formula: C₂₀H₄₄N₄O₁₈S₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 692.7094

Ref: IN-DA00HB58

G-418 Disulphate

CAS: 108321-42-2

G-418 Disulphate

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Purezza: 99.9%

Colore e forma: solid

Peso molecolare: 692.71g/mol

Ref: 54-BIG0175

G-418 Sulphate solution 50mg/ml

CAS: 108321-42-2

G-418 Sulphate solution 50mg/ml

Colore e forma: Solution

Peso molecolare: 594.63088g/mol

Ref: 54-BIG0176

G418 disulphate salt

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Purezza: ≥ 720μg/mg

Colore e forma: White to almost white powder

Peso molecolare: 692.71

Ref: 7W-GA2946

G418 disulphate salt, 10% solution in water

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Colore e forma: Clear, colourless liquid

Peso molecolare: 692.71

Ref: 7W-GP6404

G-418 disulfate

CAS: 108321-42-2

G-418 disulfate

Purezza: ≥98%

Peso molecolare: 692.71g/mol

Ref: 54-BUP18758

G-418.Sulfate Solid

CAS: 108321-42-2

M01801 - G-418.Sulfate Solid

Formula: C₂₀H₄₄N₄O₁₈S₂

Purezza: >90.0%(HPLC)(N)

Colore e forma: Solid

Peso molecolare: 692.7

Ref: 10-M01801

Geneticin Disulfate

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Peso molecolare: 496.56 2*98.07

Ref: 4Z-G-215001

G-418 disulfate

CAS: 108321-42-2

G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the elongation step in cells.

Formula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Purezza: 98% - 99.9%

Colore e forma: White To Off-White Powder

Peso molecolare: 692.71

Ref: TM-T6512

Geneticin sulfate

CAS: 108321-42-2

Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 692.71 g/mol

Ref: 3D-AG11347

G418 Disulfate

CAS: 108321-42-2, 49863-47-0

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Purezza: >90.0%(HPLC)(N)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 692.70

Ref: 3B-G0349

G-418 Sulphate (Geneticin) for tissue culture

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Colore e forma: White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellow

Peso molecolare: 692.70

Ref: SR-87858

G-418 Sulphate (Geneticin) extrapure

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂SO₄

Colore e forma: White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellow

Peso molecolare: 692.70

Ref: SR-58327

G-418.Sulfate, Sterile-Filtered Solution

CAS: 108321-42-2

M01802 - G-418.Sulfate, Sterile-Filtered Solution

Formula: C₂₀H₄₄N₄O₁₈S₂

Purezza: >90.0%(HPLC)(N)

Colore e forma: Liquid

Peso molecolare: 692.7

Ref: 10-M01802

Geneticin Disulfate Salt

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀·2H₂O₄S

Colore e forma: White To Off-White

Peso molecolare: 692.71

Ref: TR-G360580

Geneticin Disulfate (G418), Antibiotic for Culture Media Use Only

CAS: 108321-42-2

Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.

Formula: C₂₀H₄₄N₄O₁₈S₂

Purezza: Min. 97.0 Area-%

Peso molecolare: 692.71 g/mol

Ref: 3D-G-2400

Geneticin Disulfate Salt

CAS: 108321-42-2

Formula: C₂₀H₄₀N₄O₁₀(H₂SO₄)

Peso molecolare: 496.56 : 2(98.07)

Ref: ST-EA-CP-G33036