CAS 1088-11-5
:2H-1,4-benzodiazepin-2-one, 7-cloro-1,3-diidro-5-fenil-
Descrizione:
2H-1,4-benzodiazepin-2-one, 7-cloro-1,3-diidro-5-fenil- è un composto chimico appartenente alla classe delle benzodiazepine, caratterizzato dai suoi anelli fusi di benzene e diazepina. Questo composto tipicamente presenta proprietà come effetti sedativi, ansiolitici e miorilassanti, rendendolo rilevante in farmacologia. La presenza di un atomo di cloro nella posizione 7 e di un gruppo fenile nella posizione 5 contribuisce alla sua reattività chimica unica e attività biologica. Viene spesso studiato per le sue potenziali applicazioni terapeutiche, in particolare nel trattamento dell'ansia e dei disturbi del sonno. La struttura del composto consente interazioni con il sistema nervoso centrale, principalmente attraverso la modulazione dei recettori GABA, che sono cruciali per la neurotrasmissione inibitoria. Inoltre, la sua solubilità e stabilità possono variare in base alle condizioni ambientali, influenzando la sua biodisponibilità e efficacia. Le precauzioni di sicurezza e di gestione sono essenziali a causa delle sue proprietà farmacologiche, ed è soggetto a controlli normativi in molte giurisdizioni.
Formula:C15H11ClN2O
InChI:InChI=1/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)
InChI key:InChIKey=AKPLHCDWDRPJGD-UHFFFAOYSA-N
SMILES:ClC=1C=C2C(=NCC(=O)NC2=CC1)C3=CC=CC=C3
Sinonimi:- 1-Demethyldiazepam
- 7-Chloro-1,3-dihydro-1H-5-phenyl-2H-1,4-benzodiazepin-2-one
- 7-Chloro-1,3-dihydro-5-phenyl-1,4-benzodiazepin-2-one
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazapin-2-one
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-one
- 7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- 7-Chloro-5-phenyl-1,3-dihydrobenzo[e][1,4]diazepin-2-one
- 7-Chloro-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one
- 7-Chloro-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one
- 7-Chloro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
- 7-Chloro-5-phenyl-2-oxo-1,2-dihydro-1,4-benzodiazepine
- 7-Chloro-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one
- A 101
- Calmday
- Dealkylprazepam
- Demethyldiazepam
- Demoxazepam
- Desalkylprazepam
- Desmethyldiazepam
- Dmdz
- Madar
- N-Demethyldiazepam
- N-Deoxydemoxepam
- N-Descyclopropylmethylprazepam
- N-Desmethyldiazepam
- N1-Desmethyldiazepam
- N<sup>1</sup>-Desmethyldiazepam
- Nordaz
- Nordazepam
- Nordiazepam
- Norprazepam
- Nsc 46078
- Nsc 631619
- Praxadium
- Ro 5-2180
- Sigma D 7282
- Stilny
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-
- 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-
- DIAZEPAM, DESMETHYL (RO 5-2180, NORDIAZE P
- 7-Chloro-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
- N-Deoxydemoxapam
- 1,4-BENZODIAZEPIN-2-ONE,7-CHLORO-1,3-DIHYDRO-5-PHENYL-
- NDD
- Nordiazepam solution
- Nordazepam CIV (50 mg) (7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one)
- Methanol (test Nordiazepam,1.0mg/mL)
- Ro 52180434
- Chlordesmethyldiazepam
- 7-Chloro-1,3-dihydro-5-phenyl-
- Clorazepate (break down)
- 1,3-Dihydro-7-Chloro-5-Phenyl-2H-1
- DESMETHYLDIAZEPAM METHANOL SOLUTION
- Diazepam EP impurity A
- Desmethyldiazepam solution
- 1,3-Dihydro-7-Chloro-5-Phenyl-2H-1,4-Benzodiazepine-2-One
- DESMETHYLDIAZEPAM--DEA SCHEDULE IV ITEM
- NDZ
- 7-chloro-1,3-dihydro-5-phenyl-2h-4-benzodiazepin-2-one
- Vedi altri sinonimi
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
12 prodotti.
Desmethyldiazepam (Nordazepam), 1mg/ml in Methanol
CAS:Prodotto controllatoColore e forma:Single SolutionNordazepam (Nordiazepam) 0.1 mg/ml in Methanol
CAS:Prodotto controllatoColore e forma:Single SolutionNordazepam (Nordiazepam) 1.0 mg/ml in Methanol
CAS:Prodotto controllatoColore e forma:Single SolutionNordiazepam-d5 (phenyl-d5)
CAS:Prodotto controllatoPurezza:99 atom % DColore e forma:White SolidPeso molecolare:275.757-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one (Nordazepam)
CAS:Prodotto controllatoColore e forma:NeatRef: ST-EA-CP-D18001
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaNordazepam
CAS:Prodotto controllato<p>Applications The primary metabolite of Diazepam. A ligand for the GABAA receptor benzodiazepine modulatory site. Anxiolytic.Controlled substance (depressant).<br>References Klotz, U., et al.: Br. J. Clin. Pharmacol., 7, 119 (1979), Konishi, M., et al.: J. Pharm. Sci., 67, 1777 (1978), Andreoli, V., et al.: Arzneim.-Forsch., 27, 436 (1977), Miller, R.P., et al.: Toxicol. Appl. Pharmacol., 25, 453 (1973), Margolis, J., et al.: Drug Metab. Dispos., 31, 606 (2003),<br></p>Formula:C15H11ClN2OColore e forma:White To Light YellowPeso molecolare:270.71Desmethyl diazepam
CAS:Prodotto controllato<p>Diazepam is a long-acting benzodiazepine drug that is used for the treatment of a variety of conditions, such as anxiety, insomnia, muscle spasms, and alcohol withdrawal. Diazepam has been shown to have anti-convulsant properties. The hydroxyl group on diazepam's side chain is converted to an ester in order to make it more lipid soluble and therefore more readily absorbed by the body. This conversion occurs partially through the action of enzymes found in the liver microsomes of rats and humans. Desmethyldiazepam (DMDZ) is formed from diazepam by the enzyme monoamine oxidase (MAO). DMDZ has similar pharmacological properties to its parent compound but with a shorter duration of action.<br>Maternal blood levels of DMDZ are higher than those found in serum or plasma, which may be due to differences in protein binding between these two compartments.</p>Formula:C15H11ClN2OPurezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:270.71 g/molNordazepam (1.0 mg/mL in Methanol)
CAS:Prodotto controllatoFormula:C15H11ClN2OColore e forma:Single SolutionPeso molecolare:270.71Nordazepam CIV (7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one)
CAS:Prodotto controllatoAlprazolam(inn), camazepam (inn), chlordiazepoxide (inn), clonazepam (inn), clorazepate & other heterocyclic compounds with nitro atom(s) onlyFormula:C15H11ClN2OColore e forma:Light Yellow White PowderPeso molecolare:270.05599
