CAS 108930-17-2

H 7 diidrocloruro

Descrizione:

H7 diidrossicloruro, con il numero CAS 108930-17-2, è un composto chimico che tipicamente presenta caratteristiche associate alla sua struttura molecolare e ai gruppi funzionali. Come sale di diidrossicloruro, è probabile che sia un solido cristallino stabile a temperatura ambiente, solubile in acqua e in altri solventi polari grazie alla presenza di ioni cloruro. Il composto può presentare proprietà basiche, poiché deriva da una base che è stata protonata con acido cloridrico. Le sue interazioni molecolari possono includere legami idrogeno, che possono influenzare la sua solubilità e reattività. H7 diidrossicloruro può essere utilizzato in varie applicazioni, comprese le formulazioni farmaceutiche, dove potrebbe fungere da principio attivo o da agente stabilizzante. Le schede di sicurezza normalmente indicherebbero precauzioni di manipolazione, come avviene per molte sostanze chimiche, per mitigare i rischi associati all'esposizione. In generale, le caratteristiche specifiche di H7 diidrossicloruro dipenderebbero dalla sua precisa struttura molecolare e dal contesto del suo utilizzo.

Formula: C₁₄H₁₇N₃O₂S·2ClH

InChI: InChI=1S/C14H17N3O2S.2ClH/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14;;/h2-6,10-11,16H,7-9H2,1H3;2*1H

InChI key: InChIKey=OARGPFMFRLLKPF-UHFFFAOYSA-N

SMILES: S(=O)(=O)(C=1C2=C(C=CC1)C=NC=C2)N3C(C)CNCC3.Cl

Sinonimi:

• (+/-)-1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 2Hcl
• (+/-)-1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Dihydrochloride
• (+/-)-1-(5-Isoquinolinesulphonyl)-2-Methylpiperazine Dihydrochloride
• (-)-1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine, Di-Hcl Salt
• (3R)-4-(isoquinolin-5-ylsulfonyl)-3-methylpiperazin-1-ium
• (3S)-4-(isoquinolin-5-ylsulfonyl)-3-methylpiperazin-1-ium
• 1-(5-Isoquinolinylsulfonyl)-2-Methyl-Piperazine Dihydrochloride
• 5-[(2-Methylpiperazin-1-Yl)Sulfonyl]Isoquinoline Dihydrochloride
• 5-[(2-Methylpiperazin-1-Yl)Sulfonyl]Isoquinoline Hydrochloride
• H-7
• Isoquinoline, 5-[(2-methyl-1-piperazinyl)sulfonyl]-, hydrochloride (1:2)
• Piperazine, 1-(5-isoquinolinylsulfonyl)-2-methyl-, dihydrochloride

H-7 dihydrochloride

CAS: 108930-17-2

Protein kinase inhibitor. Inhibits cyclic nucleotide dependent protein kinase (PKA) and protein kinase C This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa A

Formula: C₁₄H₁₇N₃O₂S•2HCl

Peso molecolare: 364.29

Ref: 02-J61697

Protein kinase inhibitor H-7 2HCl

CAS: 108930-17-2

Formula: C₁₄H₁₉Cl₂N₃O₂S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 364.2906

Ref: IN-DA007TT5

Protein kinase inhibitor H-7 dihydrochloride

CAS: 108930-17-2

Protein kinase inhibitor H-7 dihydrochloride

Purezza: ≥98%

Peso molecolare: 364.29g/mol

Ref: 54-BUP06296

H-7 dihydrochloride

CAS: 108930-17-2

Formula: C₁₄H₁₇N₃O₂S₂HCl

Peso molecolare: 364.29

Ref: 7W-GK5980

Protein kinase inhibitor H-7 dihydrochloride

CAS: 108930-17-2

Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.

Formula: C₁₄H₁₉Cl₂N₃O₂S

Purezza: 99.54%

Colore e forma: White Crystalline Solid

Peso molecolare: 364.29

Ref: TM-T22831

1-(5-Isoquinolinesulfonyl)-2-methylpiperazine Dihydrochloride

Prodotto controllato

CAS: 108930-17-2

Applications A selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases.
References Hidaka, H. and Kawamoto, S.: Biochem. and Biophys. Res. Comm., 125, 1, 258 (1984)

Formula: C₁₄H₁₇N₃O₂S·2ClH

Colore e forma: Neat

Peso molecolare: 364.29

Ref: TR-I885000

H-7 dihydrochloride

CAS: 108930-17-2

H-7 is a cytostatic agent that inhibits the activation of transcription by inhibiting the synthesis of DNA and RNA. H-7 has shown to be an effective inhibitor of epidermal growth factor and α subunit, which are involved in the proliferation of cancer cells. In addition, H-7 can inhibit calcium ion influx into the cell, which may cause cell death. This drug also has potent inducers effects on primary cells, such as HL-60 cells, and induces apoptosis in carcinoma cell lines. H-7 is not an inhibitor of cyclase activity but enhances it when added with guanine nucleotide binding proteins (G proteins) activators such as forskolin. This leads to increased levels of cyclic AMP. As a result, H-7 inhibits protein synthesis and activates cytosolic calcium channels.

Formula: C₁₄H₁₇N₃O₂S·2HCl

Purezza: Min. 95%

Peso molecolare: 364.29 g/mol

Ref: 3D-IEA93017