CAS 1093978-89-2

2H-1-Benzazepin-2-one,6-fluoro-1,3,4,5-tetraidro-3-[4-[3-metossi-4-(4-metil-1H-imidazol-1-il)fenil]-1H-1,2,3-triazol-1-il]-1-(2,2,2-trifluoroetil)-

Descrizione:

2H-1-Benzazepina-2-one, 6-fluoro-1,3,4,5-tetraidro-3-[4-[3-metossil-4-(4-metil-1H-imidazol-1-il)fenile]-1H-1,2,3-triazol-1-il]-1-(2,2,2-trifluoroetile)-, identificato dal numero CAS 1093978-89-2, è un composto organico complesso caratterizzato dalla sua struttura multiciclica, che include un nucleo di benzazepina fuso con un moiety di triazolo e imidazolo. La presenza di un atomo di fluoro e di un gruppo trifluoroetile suggerisce potenziali applicazioni in chimica medicinale, in particolare nello sviluppo di farmaci con attività biologica o selettività migliorate. I sostituenti metossil e metilici possono influenzare la solubilità e la lipofilia del composto, influenzando le sue proprietà farmacocinetiche. Inoltre, la disposizione intricata dei gruppi funzionali indica potenziale per diverse interazioni con bersagli biologici, rendendolo un candidato per ulteriori indagini nella scoperta di farmaci. In generale, questo composto esemplifica la complessità spesso riscontrata nella chimica organica sintetica moderna, in particolare nel contesto della progettazione di molecole per uso terapeutico.

Formula: C₂₅H₂₂F₄N₆O₂

Sinonimi:

• 6-fluoro-3-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one
• 2H-1-benzazepin-2-one, 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-
• 2H-1-Benzazepin-2-one 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-
• 6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-Benzazepin-2-one
• gaMMa-secretase Modulator 2
• 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-Benzazepin-2-on
• Merck gamma-secretase modulator
• gamma secretase modulator 2,gammasecretase modulator 2
• 6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-Methoxy-4-(4-Methyl-1H-iMidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-
• Merck γ-secretase Modulator

6-Fluoro-1,3,4 ,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1 ,2,3-triazol-1-yl]-1-(2-trifluoroethyl)-2H-1-benzazepin-2-one

CAS: 1093978-89-2

6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-- 1,2,3-triazol-1yl]-1-(2trifluoroethyl)-2H-1benzazepin-2one (6FTH) is an anticancer drug that belongs to the class of benzothiazole derivatives. It has been shown to have potent antiangiogenic and antiproliferative properties in preclinical studies. 6FTH has been shown to be effective against colon cancer and breast cancer cells in vitro. It also inhibits the growth of squamous cell carcinoma cells by downregulating the expression of proteins involved in tumorigenesis. The compound has been found to be safe when used as an adjuvant to a combination therapy containing cisplatin

Formula: C₂₅H₂₂F₄N₆O₂

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 514.48 g/mol

Ref: 3D-FB151723

6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-benzazepin-2-one

Prodotto controllato

CAS: 1093978-89-2

Formula: C₂₅H₂₂F₄N₆O₂

Colore e forma: Neat

Peso molecolare: 514.475

Ref: TR-F257310

γ-secretase modulator 2

CAS: 1093978-89-2

Gamma-secretase modulator 2 selectively targets Alzheimer's by reducing Aβ(1-42), aiding in prevention and treatment.

Formula: C₂₅H₂₂F₄N₆O₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 514.47

Ref: TM-T11359