CAS 1094-61-7

beta-nicotinamide mononucleotide

Descrizione:

beta-nicotinamide mononucleotide (NMN) è un nucleotide derivato da ribosio, nicotinamide e fosfato. Svolge un ruolo cruciale nel metabolismo cellulare come precursore del dinucleotide di nicotinamide e adenina (NAD+), una coenzima vitale coinvolta nelle reazioni redox e nella produzione di energia all'interno delle cellule. NMN è riconosciuto per i suoi potenziali benefici per la salute, in particolare nella ricerca sull'invecchiamento, poiché può aiutare ad aumentare i livelli di NAD+, che tendono a diminuire con l'età. Questo composto si trova tipicamente in piccole quantità in vari alimenti, tra cui verdure e frutta. NMN è solubile in acqua, consentendo una facile assorbimento nei sistemi biologici. La sua stabilità può essere influenzata da fattori come pH e temperatura, che sono considerazioni importanti nello stoccaggio e nella formulazione. La ricerca su NMN si è ampliata, concentrandosi sulle sue implicazioni per la salute metabolica, la neuroprotezione e la longevità complessiva. Tuttavia, sebbene promettente, sono necessari ulteriori studi per comprendere appieno i suoi meccanismi e il potenziale terapeutico.

Formula: C₁₁H₁₅N₂O₈P

InChI: InChI=1/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/m1/s1

InChI key: InChIKey=DAYLJWODMCOQEW-TURQNECASA-N

SMILES: O[C@H]1[C@@H](O[C@H](COP(=O)([O-])O)[C@H]1O)[N+]=2C=C(C(N)=O)C=CC2

Sinonimi:

• 3-(Aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium
• 3-Carbamoyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosylpyridinium hydroxide, 5′-phosphate, inner salt
• 3-carbamoyl-1-(5-O-phosphonopentofuranosyl)pyridinium
• 3-carbamoyl-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridinium
• NMN
• NMN (mononucleotide)
• Nicotinamide mononucleotide
• Nicotinamide ribonucleoside 5′-phosphate
• Nicotinamide ribonucleotide
• Nicotinamide ribotide
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)-, inner salt
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-, hydroxide, inner salt
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-, inner salt
• Pyridinium, 3-carbamoyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, hydroxide, 5′-(dihydrogen phosphate), inner salt
• coenzyme NMN
• β-<span class="text-smallcaps">D</span>-NMN
• β-NMN
• β-Nicotinamide mononucleotide
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-, inner salt
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-, hydroxide, inner salt
• 3-Carbamoyl-1-β-D-ribofuranosylpyridinium hydroxide, 5′-phosphate, inner salt
• Pyridinium, 3-carbamoyl-1-β-D-ribofuranosyl-, hydroxide, 5′-(dihydrogen phosphate), inner salt
• β-Nicotinamide ononucleotide
• beta-D-NMN
• Nicotinamide nucleotide
• β-nicotinamide D-ribonucleotide
• NMN zwitterion
• β-Nicotinamide Moonucleotide
• Nicotimide mononucleotide
• 99% NMN CAS 1094 61 7
• β-Nicotinamide Mononucleotid
• Nicotinamide mononuclotide
• β-Nicotinamidse Mononucleotide
• β-D-NMN
• beta-Nicotinamide Moonucleotide
• NMN powder
• BETA-NMN POWDER

β-Nicotinamide mononucleotide

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 334.2192

Ref: IN-DA003880

β-Nicotinamide mononucleotide

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purezza: ≥ 95.0%

Colore e forma: White, off-white or pale yellow powder

Peso molecolare: 334.22

Ref: 7W-GE9996

β-Nicotinamide Mononucleotide-13C6

CAS: 1094-61-7

Formula: C₅₁₃C₆H₁₅N₂O₈P

Peso molecolare: 340.17

Ref: 4Z-N-133013

β-Nicotinamide mononucleotide

CAS: 1094-61-7

β-Nicotinamide mononucleotide

Purezza: ≥98%

Peso molecolare: 334.22g/mol

Ref: 54-BUP15443

β-Nicotinamide Mononucleotide Sodium Salt

CAS: 1094-61-7

Formula: C₁₁H₁₄N₂O₈P·Na

Peso molecolare: 333.21 22.99

Ref: 4Z-N-133014

Nicotinamide mononucleotide

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purezza: 95%~99%

Peso molecolare: 334.221

Ref: BP-BP4241

β-Nicotinamide Mononucleotide

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 334.22

Ref: 3B-N1123

β-Nicotinamide mononucleotide

CAS: 1094-61-7

β-nicotinamide mononucleotide (NMN) is a natural nucleotide and a key intermediate in the synthesis of coenzyme I (NAD+). Cost effective and quality assured.

Formula: C₁₁H₁₅N₂O₈P

Purezza: 99.29% - >99.99%

Colore e forma: Solid

Peso molecolare: 334.22

Ref: TM-T4721

β-Nicotinamide Mononucleotide-d4

CAS: 1094-61-7

Formula: C₁₁H₁₁D₄N₂O₈P

Peso molecolare: 338.25

Ref: 4Z-N-133006

β-Nicotinamide Mononucleotide-13C5

CAS: 1094-61-7

Formula: C₆₁₃C₅H₁₅N₂O₈P

Peso molecolare: 339.18

Ref: 4Z-N-133007

b-Nicotinamide mononucleotide

CAS: 1094-61-7

b-Nicotinamide mononucleotide

Formula: C₁₁H₁₅N₂O₈P

Purezza: By hplc: 99.5% by area (Typical Value in Batch COA)

Colore e forma: white powder

Peso molecolare: 334.21916g/mol

Ref: 54-BIB3016

β-Nicotinamide Mononucleotide

CAS: 1094-61-7

Stability Very Hygroscopic
Applications A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
References Yoshino, J. et al.: Cell Metab., 14, 528 (2011); Caton, P.W. et al.: Diabetologia, 54, 3083 (2011); Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2009);

Formula: C₁₁H₁₅N₂O₈P

Colore e forma: White

Peso molecolare: 334.22

Ref: TR-N407765

β-Nicotinamide-d4 Mononucleotide (d4-major)

Prodotto controllato

CAS: 1094-61-7

Formula: C₁₁D₄H₁₁N₂O₈P

Colore e forma: White To Off-White

Peso molecolare: 338.244

Ref: TR-N407768

b-Nicotinamide mononucleotide

CAS: 1094-61-7

b-Nicotinamide mononucleotide, or NMN, is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells that is essential for various metabolic processes. NAD+ is involved in critical functions such as DNA repair, gene expression, and cellular stress responses.

Formula: C₁₁H₁₅N₂O₈P

Purezza: Min. 95 Area-%

Colore e forma: Powder

Peso molecolare: 334.22 g/mol

Ref: 3D-NN45555

ß-Nicotinamide Mononucleotide (ß-NMN) extrapure, 98%

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purezza: min. 98.0%

Colore e forma: White, Crystalline powder

Peso molecolare: 334.22

Ref: SR-95130

ß-Nicotinamide Mononucleotide (ß-NMN) for cell culture, 99%, Endotoxin (BET) 0.05EU/mg

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purezza: min. 99.0%

Colore e forma: White, Crystalline powder.

Peso molecolare: 334.22

Ref: SR-63509

((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 334.221

Ref: 10-F455506

β-Nicotinamide Mononucleotide-13C5

Prodotto controllato

CAS: 1094-61-7

Applications The labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
References Yoshino, J. et al.: Cell Metab., 14, 528 (2011); Caton, P.W. et al.: Diabetologia, 54, 3083 (2011); Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2009);

Formula: C₅C₆H₁₅N₂O₈P

Colore e forma: Neat

Peso molecolare: 339.182

Ref: TR-N407767