CAS 109806-71-5

2-[4-[(4-clorofenil)-fenilmetil]piperazin-1-il]etanolo

Descrizione:

2-[4-[(4-clorofenil)-fenilmetil]piperazin-1-il]etanolo, con il numero CAS 109806-71-5, è un composto chimico che appartiene alla classe dei derivati della piperazina. Questa sostanza presenta un anello di piperazina, che è un anello a sei membri contenente due atomi di azoto, ed è sostituito con un gruppo fenilmetile e un gruppo 4-clorofenile. La presenza del gruppo idrossile (-OH) nella parte di etanolo della molecola contribuisce alla sua potenziale solubilità in solventi polari. Questo composto è spesso studiato per le sue proprietà farmacologiche, in particolare nel contesto della neurofarmacologia, poiché i derivati della piperazina sono noti per mostrare varie attività biologiche, inclusi effetti antipsicotici e ansiolitici. La sostituzione clorofenilica può influenzare la sua interazione con obiettivi biologici, potenzialmente migliorando la sua efficacia o alterando il suo profilo farmacocinetico. In generale, le caratteristiche strutturali di questo composto suggeriscono che potrebbe avere implicazioni significative nella chimica medicinale e nello sviluppo di farmaci.

Formula: C₁₉H₂₅Cl₃N₂O

InChI: InChI=1S/C19H23ClN2O/c20-18-8-6-17(7-9-18)19(16-4-2-1-3-5-16)22-12-10-21(11-13-22)14-15-23/h1-9,19,23H,10-15H2

InChI key: InChIKey=ZJQSBXXYLQGZBR-UHFFFAOYSA-N

SMILES: C(N1CCN(CCO)CC1)(C2=CC=C(Cl)C=C2)C3=CC=CC=C3

Sinonimi:

• 1-Piperazineethanol, 4-(p-chloro-α-phenylbenzyl)-
• 1-Piperazineethanol, 4-[(4-chlorophenyl)phenylmethyl]-
• 2-[4-{4-Chlorophenyl} Phenylmethyl]-1-Piperazinylethanol
• 2-{4-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-piperazin-1-YL}-ETHANOL
• 2-{4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethanol
• 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazine
• 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol
• Cetirizine ethanol
• Cetirizine impurity G
• Unii-Pgv947X9B1
• 2-[4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]ethanol
• Cetirizine Impurity 15 Monomer （Cetirizine EP Impurity G Monomer ）
• 4-[(4-Chlorophenyl)phenylMethyl]-(4-hydroxy-1-piperidinyl)-1-butanone
• 2-[4-{Chlorophenyl}Phenylmethyl]-1-
• Levocetirizine Impurity G
• 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol
• Cetirizine -EP-Imp-G
• Levocetirizine Impurity 6
• Cetirizine EP Impurity G Hydrochloride

Cetirizine EP Impurity G (Cetirizine USP Related Compound G (Free Form), Levocetirizine EP Impurity H)

CAS: 109806-71-5

Formula: C₁₉H₂₃ClN₂O

Colore e forma: Pale Yellow Semi-Solid (Low M P )

Peso molecolare: 330.86

Ref: 4Z-C-2012

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol

CAS: 109806-71-5

Stability Very Hygroscopic
Applications 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine.
References Rezaei, Z. et al.: Archiv. Pharm., 344, 658 (2011)

Formula: C₁₉H₂₃ClN₂O

Colore e forma: White To Off-White

Peso molecolare: 330.85

Ref: TR-C377565

2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL]PIPERAZIN-1-YL]ETHANOL

CAS: 109806-71-5

Formula: C₁₉H₂₅Cl₃N₂O

Purezza: 95.0%

Peso molecolare: 403.77

Ref: 10-F540017

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol-d4

Prodotto controllato

CAS: 109806-71-5

Formula: C₁₉H₁₉D₄ClN₂O

Colore e forma: Neat

Peso molecolare: 334.88

Ref: TR-C377567

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride

CAS: 109806-71-5

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride is a cholinergic drug that is used to treat allergic rhinitis in children and adults. It has been shown to be well tolerated in pediatric patients and geriatric patients, as well as being an innovative, labile, and biopharmaceutical compound. 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride is not metabolized by the liver and does not have significant side effects. It has a low potential for abuse because of its low solubility in water. It is an antihistamine that blocks the action of histamine at H1 receptors on smooth muscle cells in the nose, which helps reduce nasal congestion and sneezing.

Formula: C₁₉H₂₃ClN₂O·2HCl

Purezza: Min. 95%

Peso molecolare: 403.77 g/mol

Ref: 3D-FC53582