CAS 109838-85-9

(R)-2,5-diidro-3,6-dimetossi-2-isopropilpirazina

Descrizione:

(R)-2,5-diidro-3,6-dimetossi-2-isopropilpirazina è un composto chimico caratterizzato dalla sua unica struttura ad anello di pirazina, che contribuisce alle sue proprietà aromatiche. Questo composto presenta due gruppi metossilici (-OCH3) nelle posizioni 3 e 6, migliorando la sua solubilità e reattività. La presenza di un gruppo isopropilico nella posizione 2 aggiunge al suo ingombro sterico, influenzando le sue interazioni e potenziali applicazioni. Come molecola chirale, esiste in due forme enantiomeriche, con la configurazione (R) di particolare interesse in vari campi, inclusa la chimica dei sapori e delle fragranze, grazie alle sue distintive caratteristiche sensoriali. Il composto è tipicamente sintetizzato attraverso reazioni organiche specifiche che consentono l'introduzione selettiva di gruppi funzionali. Le sue applicazioni possono estendersi all'industria alimentare, dove può essere utilizzato come agente aromatizzante, così come nello sviluppo di fragranze. In generale, (R)-2,5-diidro-3,6-dimetossi-2-isopropilpirazina è notevole per le sue caratteristiche strutturali e il suo potenziale utilizzo in varie applicazioni chimiche.

Formula: C₉H₁₆N₂O₂

InChI: InChI=1/C9H16N2O2/c1-6(2)8-9(13-4)10-5-7(11-8)12-3/h6,8H,5H2,1-4H3/t8-/m1/s1

SMILES: CC(C)[C@@H]1C(=NCC(=N1)OC)OC

Sinonimi:

• (R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine
• (2R)-3,6-dimethoxy-2-(propan-2-yl)-2,5-dihydropyrazine
• (2R)-2,5-Dihydro-2-isopropyl-3,6-dimethoxypyrazine
• 2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (2R)-(-)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPYRAZINE
• (2R)-2,5-Dihydro-3,6-dimethoxy-2-(1-methylethyl)pyrazine
• BISLACTIMETHER
• (2R)-(-)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPYRAZINE, 98+%
• (2R)-3,6-DIMETHOXY-2-(1-METHYLETHYL)-2,5-DIHYDROPYRAZINE
• (R)-2,5-DIMETHOXY-3-ISOPROPYL-3,6-DIHYDROPYRAZINE
• zR{-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• SCHOELLKOPF-HARTWIG-REAGENT
• (2R)-(-)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine (aka (R )-Schollkopf reagent)
• (R)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPIPERAZINE
• (-)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (R)-Schollkopf Reagent
• Pyrazine, 2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)-, (2R)-(9CI)

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine, 98%

CAS: 109838-85-9

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazineChiral auxiliary for the synthesis of -amino acids. It is an inhibitor with antitumor activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer

Formula: C₉H₁₆N₂O₂

Purezza: 98%

Colore e forma: Colorless to yellow to orang, Liquid

Peso molecolare: 184.24

Ref: 02-H56077

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine

CAS: 109838-85-9

Formula: C₉H₁₆N₂O₂

Purezza: 96%

Colore e forma: Liquid

Peso molecolare: 184.2355

Ref: IN-DA0032ER

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine

CAS: 109838-85-9

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine

Formula: C₉H₁₆N₂O₂

Purezza: 99%

Colore e forma: colourless to light yellow liquid

Peso molecolare: 184.24g/mol

Ref: 54-OR925455

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine

CAS: 109838-85-9

Formula: C₉H₁₆N₂O₂

Purezza: >95.0%(GC)

Colore e forma: Colorless to Yellow clear liquid

Peso molecolare: 184.24

Ref: 3B-D3256

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine

CAS: 109838-85-9

Purezza: 98%

Peso molecolare: 184.238998413086

Ref: 10-F790908

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine

CAS: 109838-85-9

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine and its enantiomer (S)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine are also known as Schöllkopf chiral auxiliaries or Schöllkopf reagents, and are used to produce optically pure α-amino acids via asymmetric synthesis. The Schöllkopf reagent can be deprotonated at the prochiral α-carbon, and the resulting enolate is trapped with electrophiles to yield adducts with high (typically > 95% d.e.) diastereoselectivity. The enolate is essentially planar, and the steric bulk of the isopropyl group directs the incoming electrophile to attack from the opposite face, yielding trans adducts. A wide range of electrophiles including alkyl halides, alkyl sulfonates, acyl chlorides, aldehydes, ketones, epoxides, thioketones and enones can be used. Hydrolysis, typically under mild acidic conditions, yields the non-substituted amino acid with high (typically > 95 e.e.) enantiopurity.

Formula: C₉H₁₆N₂O₂

Purezza: Min. 98%

Colore e forma: Colorless Yellow Clear Liquid

Peso molecolare: 184.24 g/mol

Ref: 3D-FD04039

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine (>85% Purity)

Prodotto controllato

CAS: 109838-85-9

Stability Moisture Sensitive
Applications An inhibitor with antitumor activity.
References Plumb, J., et al.: Mol. Cancer Ther., 2, 721 (2003), de Ruijter, A., et al.: Biochem. J., 370, 737 (2003), Dey, P., et al.: Curr. Med. Chem., 13, 2909 (2006), Maiso, P., et al.: Cancer Res., 66, 5781 (2006), Paris, M., et al.: J. Med. Chem., 51, 1505 (2008),

Formula: C₉H₁₆N₂O₂

Purezza: >85%

Colore e forma: Neat

Peso molecolare: 184.24

Ref: TR-I824430