CAS 11051-90-4

(3β,11α,12β,14β)-11-(Acetilossi)-3-[(O-6-desossi-3-O-metil-β-D-allopiranosil-(1→4)-O-2,6-didesossi-3-O-metil-β-D-arabino-eso-piranosil-(1→4)-2,6-didesossi-3-O-metil-β-D-ribo-eso-piranosil)ossi]-14-idrossi-12-[(1-osso-3-fenil-2-propen-1-il)ossi]pregnan-20-one

Descrizione:

La sostanza chimica con il nome "(3β,11α,12β,14β)-11-(Acetilossi)-3-[(O-6-desossi-3-O-metil-β-D-allopiranosil-(1→4)-O-2,6-didesossi-3-O-metil-β-D-arabino-eso-piranosil-(1→4)-2,6-didesossi-3-O-metil-β-D-ribo-eso-piranosil)ossi]-14-idrossi-12-[(1-osso-3-fenil-2-propen-1-il)ossi]pregnan-20-one" è una molecola organica complessa caratterizzata dal suo scheletro steroideo, tipico dei pregnani. Questo composto presenta più gruppi funzionali, tra cui acetossido, idrossido e legami glicosidici, indicando la sua potenziale attività biologica e interazione con vari sistemi biologici. La presenza di unità zuccherine suggerisce che potrebbe mostrare proprietà legate alla glicosilazione, che possono influenzare la solubilità, la stabilità e la bioattività. Il gruppo fenile attaccato alla molecola suggerisce possibili interazioni aromatiche, che potrebbero svolgere un ruolo nei suoi effetti farmacologici. In generale, la struttura intricata di questo composto suggerisce che potrebbe avere implicazioni significative nella chimica medicinale, in particolare nello sviluppo di agenti terapeutici. Il suo numero CAS, 11051-90-4, consente un'identificazione precisa nei database chimici e nella letteratura.

Formula: C₅₃H₇₈O₁₇

InChI: InChI=1S/C53H78O17/c1-27(54)35-21-23-53(59)36-18-17-33-24-34(20-22-51(33,6)42(36)47(66-31(5)55)49(52(35,53)7)68-39(56)19-16-32-14-12-11-13-15-32)67-40-25-37(60-8)45(29(3)63-40)69-41-26-38(61-9)46(30(4)64-41)70-50-44(58)48(62-10)43(57)28(2)65-50/h11-16,19,28-30,33-38,40-50,57-59H,17-18,20-26H2,1-10H3

InChI key: InChIKey=ZKWQLHAAXWFVPF-UHFFFAOYSA-N

SMILES: O(C(C)=O)C1C2C(C3(O)C(C)(C1OC(C=CC4=CC=CC=C4)=O)C(C(C)=O)CC3)CCC5C2(C)CCC(OC6CC(OC)C(OC7CC(OC)C(OC8C(O)C(OC)C(O)C(C)O8)C(C)O7)C(C)O6)C5

Sinonimi:

• (3β,11α,12β,14β)-11-(Acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-<span class="text-smallcaps">D</smallcap>-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propen-1-yl)oxy]pregnan-20-one
• (3β,8xi,9xi,11α,12β,14β)-11-(acetyloxy)-3-{[6-deoxy-3-O-methyl-β-D-allopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl]oxy}-14-hydroxy-20-oxopregnan-12-yl (2E)-3-phenylprop-2-enoate
• Condurango glycoside A
• Pregnan-20-one, 11-(acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-<span class="text-smallcaps">D</smallcap>-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propen-1-yl)oxy]-, (3β,11α,12β,14β)-
• Pregnan-20-one, 11-(acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-<span class="text-smallcaps">D</smallcap>-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propenyl)oxy]-, (3β,11α,12β,14β)-
• (3β,11α,12β,14β)-11-(Acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propen-1-yl)oxy]pregnan-20-one
• Pregnan-20-one, 11-(acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propen-1-yl)oxy]-, (3β,11α,12β,14β)-
• Pregnan-20-one, 11-(acetyloxy)-3-[(O-6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[(1-oxo-3-phenyl-2-propenyl)oxy]-, (3β,11α,12β,14β)-

Condurango glycoside A

CAS: 11051-90-4

Condurango glycoside A activates p53, induces ROS generation, up-regulates p53 expression, and triggers apoptosis as well as premature senescence associated

Formula: C₅₃H₇₈O₁₇

Colore e forma: Solid

Peso molecolare: 987.18

Ref: TM-T79991

Condurango glycoside a

CAS: 11051-90-4

Natural glycoside

Formula: C₅₃H₇₈O₁₇

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 987.18

Ref: 5G-83941

Condurangoglykosid A

CAS: 11051-90-4

Condurangoglykosid A is a natural product and an anticancer drug that has shown to be effective in the treatment of prostate cancer. This drug inhibits the growth of tumour cells by preventing necrosis factor from binding to the cell membrane, which prevents the release of cytochrome C from mitochondria. Condurangoglykosid A also protects liver cells from damage and death by inhibiting toxins that are released into the body during cancer treatment. Condurangoglykosid A also inhibits tumor growth by blocking nuclear factor kappa-light-chain-enhancer (NFκB) activation in cancer cells. This drug can be administered orally and has been shown to be safe for human use. It has been observed that Condurangoglykosid A may have an antitumor effect on cervical cancer cells, but this has not been confirmed yet.

Formula: C₅₃H₇₈O₁₇

Purezza: Min. 95%

Peso molecolare: 987.2 g/mol

Ref: 3D-LAA05190