CAS 11061-68-0

insulina umana

Descrizione:

insulina umana, con il numero CAS 11061-68-0, è un ormone peptidico prodotto dal pancreas che svolge un ruolo cruciale nel metabolismo del glucosio. È composto da 51 aminoacidi e ha un peso molecolare di circa 5.800 dalton. L'insulina funziona principalmente per abbassare i livelli di glucosio nel sangue facilitando l'assorbimento del glucosio nelle cellule, in particolare nel tessuto muscolare e adiposo, e inibendo la produzione epatica di glucosio. La struttura dell'insulina consiste in due catene, A e B, collegate da legami disolfuro, essenziali per la sua attività biologica. L'insulina viene tipicamente somministrata per iniezione a causa della sua natura proteica, poiché non è efficace se assunta per via orale a causa della degradazione nel tratto gastrointestinale. Viene utilizzata terapeuticamente nella gestione del diabete mellito, aiutando a controllare i livelli di zucchero nel sangue in individui con carenza o resistenza all'insulina. insulina umana è prodotto attraverso la tecnologia del DNA ricombinante, garantendo un approvvigionamento costante e sicuro per uso medico.

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

InChI: InChI=1/C257H383N65O77S6/c1-29-131(23)205(313-193(339)104-259)252(393)317-204(130(21)22)248(389)288-159(75-82-200(349)350)217(358)282-156(71-78-189(263)335)221(362)308-183-116-403-404-117-184-243(384)305-178(111-324)240(381)294-162(88-123(7)8)225(366)295-168(95-140-53-61-146(329)62-54-140)228(369)283-154(69-76-187(261)333)218(359)290-161(87-122(5)6)223(364)285-158(74-81-199(347)348)220(361)302-174(101-190(264)336)235(376)298-170(97-142-57-65-148(331)66-58-142)231(372)309-182(242(383)304-176(255(396)397)103-192(266)338)115-402-401-114-181(214(355)273-107-194(340)278-153(72-79-197(343)344)216(357)281-151(51-42-84-271-257(267)268)212(353)272-108-195(341)279-166(93-138-46-36-32-37-47-138)227(368)297-167(94-139-48-38-33-39-49-139)230(371)299-171(98-143-59-67-149(332)68-60-143)238(379)320-208(135(27)327)254(395)322-85-43-52-186(322)246(387)286-152(50-40-41-83-258)222(363)321-209(136(28)328)256(398)399)311-250(391)203(129(19)20)316-236(377)164(90-125(11)12)292-229(370)169(96-141-55-63-147(330)64-56-141)296-224(365)160(86-121(3)4)289-210(351)133(25)277-215(356)157(73-80-198(345)346)287-247(388)202(128(17)18)315-237(378)165(91-126(13)14)293-233(374)173(100-145-106-270-120-276-145)301-239(380)177(110-323)280-196(342)109-274-213(354)180(113-400-405-118-185(310-244(183)385)245(386)319-207(134(26)326)253(394)306-179(112-325)241(382)318-206(132(24)30-2)251(392)312-184)307-226(367)163(89-124(9)10)291-232(373)172(99-144-105-269-119-275-144)300-219(360)155(70-77-188(262)334)284-234(375)175(102-191(265)337)303-249(390)201(127(15)16)314-211(352)150(260)92-137-44-34-31-35-45-137/h31-39,44-49,53-68,105-106,119-136,150-186,201-209,323-332H,29-30,40-43,50-52,69-104,107-118,258-260H2,1-28H3,(H2,261,333)(H2,262,334)(H2,263,335)(H2,264,336)(H2,265,337)(H2,266,338)(H,269,275)(H,270,276)(H,272,353)(H,273,355)(H,274,354)(H,277,356)(H,278,340)(H,279,341)(H,280,342)(H,281,357)(H,282,358)(H,283,369)(H,284,375)(H,285,364)(H,286,387)(H,287,388)(H,288,389)(H,289,351)(H,290,359)(H,291,373)(H,292,370)(H,293,374)(H,294,381)(H,295,366)(H,296,365)(H,297,368)(H,298,376)(H,299,371)(H,300,360)(H,301,380)(H,302,361)(H,303,390)(H,304,383)(H,305,384)(H,306,394)(H,307,367)(H,308,362)(H,309,372)(H,310,385)(H,311,391)(H,312,392)(H,313,339)(H,314,352)(H,315,378)(H,316,377)(H,317,393)(H,318,382)(H,319,386)(H,320,379)(H,321,363)(H,343,344)(H,345,346)(H,347,348)(H,349,350)(H,396,397)(H,398,399)(H4,267,268,271)/t131-,132-,133-,134?,135?,136?,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,201-,202-,203-,204-,205-,206-,207-,208-,209-/m0/s1

Sinonimi:

• Insulin, Zinc, Human, Recomb.

Insulin solution (4mg/mL) [Optimized for Cell Culture]

CAS: 11061-68-0

Colore e forma: Colorless to Almost colorlessclear liquid

Ref: 3B-I1257

Insulin

CAS: 11061-68-0

Insulin is a hormone that is produced by beta cells in the pancreas and regulates blood sugar levels. It is used for the treatment of diabetes mellitus, a disease in which the body does not produce enough insulin or cannot use insulin properly. Insulin works by lowering the level of glucose (sugar) in the blood, thereby regulating its supply to various parts of the body. Insulin has been shown to be effective at reducing postprandial blood glucose concentrations. This drug also lowers blood glucose concentrations by stimulating glucose uptake into muscle and adipose tissue. Insulin is also used to treat type 1 diabetes, gestational diabetes, and other conditions where low insulin production results in high blood sugar levels.

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

Purezza: Reported (%)

Colore e forma: Powder

Peso molecolare: 5,807.57 g/mol

Ref: 3D-LAA06168

Insulin (Human)

CAS: 11061-68-0

Human insulin is a peptide hormone produced by beta cells in the pancreas. The insulin receptor is found on the surface of liver, fat, and muscle cells. When binding to its receptor, insulin opens ion channels allowing potassium ions to flow into the cell and sodium ions to flow out of the cell. This change in ion concentration causes an electrical potential across the membrane that triggers an influx of calcium ions from outside the cell. These changes result in an increase in glucose uptake by tissues and inhibition of glucose production by the liver. Insulin also binds to a secondary receptor called IGF-1R (insulin-like growth factor) which activates intracellular signaling pathways involving PI3K and Akt kinase. Insulin can be used as a research tool for studying protein-protein interactions or as a pharmacological agent for diabetes treatment.  This product is enzymatically derived from Porcine Insulin A-chain, available as a 0.5mg vial and contains disulfide bonds between CysA6-CysA11,CysA7-CysB7, and CysA20-CysB19.

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

Purezza: Min. 95%

Peso molecolare: 5,807.6 g/mol

Ref: 3D-PIN-4088-V

Insulin Human, recombinant

CAS: 11061-68-0

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

Purezza: 95.0 - 105.0 % (dried basis)

Colore e forma: White to off-white powder

Peso molecolare: 5807.57

Ref: 7W-GE1021

INSULIN (HUMAN) CRS

CAS: 11061-68-0

INSULIN (HUMAN) CRS

Formula: C₄H₃BrN₂O

Peso molecolare: 174.9834

Ref: 41-I0310000

High Molecular Weight Insulin Human

CAS: 11061-68-0

Insulin and its salts

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆(monomer)

Colore e forma: White Off-White Powder

Peso molecolare: 5803.63765

Ref: 45-1342150

Insulin Human (COLD SHIPMENT REQUIRED) (DISCONTINUED)

CAS: 11061-68-0

Insulin and its salts

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

Colore e forma: White Crystals

Peso molecolare: 5803.63765

Ref: 45-1342106

Insulin (Human)

CAS: 11061-68-0

Insulin is a peptide hormone that regulates the uptake and storage of glucose by muscle and fat cells. Insulin is produced by beta cells in the pancreas, which release it into the bloodstream when blood sugar levels rise. Insulin lowers glucose levels by increasing the amount of glucose taken up from the blood into muscle and fat cells, suppressing hepatic gluconeogenesis, and promoting glycolysis. It also increases protein synthesis, decreases proteolysis, and stimulates growth. With a molecular weight of 5808 Da, insulin is composed of two polypeptide chains with an approximate molecular weight of 3120 Da each linked by disulfide bonds. Insulin has no lipid moiety or carbohydrate moiety. Insulin binds to its receptor on the surface of a cell to trigger one or more signaling cascades leading to changes in metabolism. Binding to the receptor triggers a conformational change in the receptor that causes insulin to be released from its binding site on the receptor.

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

Purezza: Min. 95%

Peso molecolare: 5,807.6 g/mol

Ref: 3D-PIN-4088-S

Insulin (Human)

CAS: 11061-68-0

Applications Insulin (Human) is a peptide hormone regulating the metabolism of carbohydrates and fats. It is used in the treatment of those suffering from the diabetes type I and II metabolic disorders. Regulates the absorption of glucose from the blood to skeletal muscles and fat storage. References Lai, Y. et al.: Biochem. J., 460, 363 (2014); Hedman, C. et al.: Clin. Endocrinol., 81, 58 (2014);

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

Colore e forma: Neat

Peso molecolare: 5807.57

Ref: TR-I666550

Insulin Human RS

CAS: 11061-68-0

Colore e forma: White Solid

Ref: 2K-1116000021

Insulin Human

CAS: 11061-68-0

Insulin and its salts

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

Colore e forma: White Lyophilized Cake

Peso molecolare: 5803.63765

Ref: 45-1342117

r-Insulin ex. Human for cell culture, 25 USP U/mg, Endotoxin (BET) 1.0EU/mg

CAS: 11061-68-0

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

Colore e forma: White, Powder

Peso molecolare: ~ 5808

Ref: SR-72828

Insulin (human)

CAS: 11061-68-0

Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood.

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

Purezza: 97.32% - 99.99%

Colore e forma: Solid

Peso molecolare: 5807.57

Ref: TM-T8221

Insulin (Human)

CAS: 11061-68-0

Formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆

Colore e forma: Liquid

Peso molecolare: 5807.5702

Ref: IN-DA008RHX