CAS 11088-09-8

Wilforina

Descrizione:

Wilforina, con il numero CAS 11088-09-8, è un composto chimico che appartiene alla classe degli alcaloidi. È principalmente derivato dalla specie vegetale Wilfordia ebracteata, nota per le sue proprietà medicinali. Il composto presenta una gamma di attività biologiche, inclusi potenziali effetti anti-infiammatori e analgesici, rendendolo di interesse nella ricerca farmacologica. Wilforina è caratterizzato dalla sua complessa struttura molecolare, che contribuisce alla sua attività biologica. Viene tipicamente studiato per le sue interazioni con vari bersagli biologici, inclusi enzimi e recettori. La solubilità, stabilità e reattività del composto possono variare a seconda delle condizioni ambientali, come pH e temperatura. Come molti alcaloidi, i profili di sicurezza e tossicità sono cruciali per la sua applicazione in chimica medicinale. La ricerca in corso mira a chiarire ulteriormente i suoi meccanismi d'azione e i potenziali usi terapeutici, in particolare nei contesti di medicina tradizionale.

Formula: C₄₃H₄₉NO₁₈

InChI: InChI=1S/C43H49NO18/c1-21-16-17-29-28(15-12-18-44-29)39(52)55-19-40(7)30-31(56-23(3)46)35(58-25(5)48)42(20-54-22(2)45)36(59-26(6)49)32(60-38(51)27-13-10-9-11-14-27)34(61-37(21)50)41(8,53)43(42,62-40)33(30)57-24(4)47/h9-15,18,21,30-36,53H,16-17,19-20H2,1-8H3/t21-,30+,31+,32-,33+,34-,35+,36-,40-,41-,42+,43-/m0/s1

InChI key: InChIKey=ZOCKGJZEUVPPPI-QSNSFFMXSA-N

SMILES: C(OC(C)=O)[C@]12[C@@]34[C@H](OC(C)=O)[C@]([C@@](C)(O3)COC(=O)C=5C(CC[C@H](C)C(=O)O[C@]([C@]4(C)O)([C@H](OC(=O)C6=CC=CC=C6)[C@@H]1OC(C)=O)[H])=NC=CC5)([C@@H](OC(C)=O)[C@H]2OC(C)=O)[H]

Sinonimi:

• Evonimine, 8-(acetyloxy)-O2-benzoyl-O2-deacetyl-8-deoxo-, (8α)-
• 8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-, (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-
• (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione
• Wilforine
• 8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-, [8R-(8R*,9R*,10R*,11S*,12S*,13R*,14R*,15S*,18S*,21S*,22S*,23R*)]-

(8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione

CAS: 11088-09-8

Formula: C₄₃H₄₉NO₁₈

Purezza: %

Peso molecolare: 867.8451

Ref: IN-DA008TNF

Wilforine

CAS: 11088-09-8

Wilforine

Purezza: ≥98%

Peso molecolare: 867.85g/mol

Ref: 54-BUP03408

Wilforine

CAS: 11088-09-8

Formula: C₄₃H₄₉NO₁₈

Peso molecolare: 867.85

Ref: 7W-GY2293

Wilforine

CAS: 11088-09-8

Wilforine has anti-inflammatory effect, which might be mediated by down-regulation of the expression of inflammatory factors TNF-α, IL-6 and NO. It also has insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system.

Formula: C₄₃H₄₉NO₁₈

Purezza: 95%~99%

Colore e forma: Powder

Peso molecolare: 867.854

Ref: BP-BP1588

Wilforine

CAS: 11088-09-8

Wilforine: a sesquiterpene alkaloid from T. wilfordii, treats pulmonary fibrosis, has anti-inflammatory and insecticidal properties.

Formula: C₄₃H₄₉NO₁₈

Purezza: 98.67% - 99.85%

Colore e forma: Solid

Peso molecolare: 867.85

Ref: TM-T6S1049

Wilforine

CAS: 11088-09-8

Natural alkaloid

Formula: C₄₃H₄₉NO₁₈

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 867.86

Ref: 5G-83298

Wilforine

CAS: 11088-09-8

Wilforine is a natural diterpenoid alkaloid derived from the root of the *Tripterygium wilfordii* plant, a species widely explored for its bioactive compounds. As a member of the alkaloid family, Wilforine exhibits a complex chemical structure that underlies its biological activities. The mode of action of Wilforine is multifaceted, involving the modulation of immune system components and inhibition of various signaling pathways. This contributes to its anti-inflammatory and immunosuppressive properties.

Formula: C₄₃H₄₉NO₁₈

Purezza: Min. 96 Area-%

Colore e forma: White Powder

Peso molecolare: 867.85 g/mol

Ref: 3D-FW74254