CAS 111011-76-8

2-(benzil-fenil-amino)etile 5-(5,5-dimetil-2-osso-1,3-diossa-2$l^{5}-fosfacicloes-2-il)-2,6-dimetil-4-(3-nitrofenil)-1,4-diidropiridina-3-carbossilato

Descrizione:

La sostanza chimica nota come "2-(benzil-fenil-amino)etile 5-(5,5-dimetil-2-osso-1,3-diossa-2$l^{5}-fosfacicloes-2-il)-2,6-dimetil-4-(3-nitrofenil)-1,4-diidropiridina-3-carbossilato," con il numero CAS 111011-76-8, è un composto organico complesso che presenta più gruppi funzionali, tra cui un gruppo amminico, un carbossilato e un moiety nitrofenilico. La sua struttura suggerisce potenziali applicazioni in chimica medicinale, in particolare nello sviluppo di farmaci grazie alla presenza del nucleo di diidropiridina, spesso associato a bloccanti dei canali del calcio. Il componente fosfacicloesano potrebbe conferire proprietà uniche, come una maggiore stabilità o bioattività. La presenza del gruppo nitro indica potenziale per una maggiore reattività o interazione con bersagli biologici. In generale, questo composto esemplifica il design intricato spesso trovato nello sviluppo di farmaci, dove vari sostituenti sono incorporati strategicamente per ottimizzare l'efficacia e la selettività. Ulteriori studi sarebbero necessari per chiarire le sue specifiche attività biologiche e potenziali applicazioni terapeutiche.

Formula: C₃₆H₄₅ClN₃O₈P

InChI: InChI=1/C34H38N3O7P.C2H6O.ClH/c1-24-30(33(38)42-19-18-36(28-15-9-6-10-16-28)21-26-12-7-5-8-13-26)31(27-14-11-17-29(20-27)37(39)40)32(25(2)35-24)45(41)43-22-34(3,4)23-44-45;1-2-3;/h5-17,20,31,35H,18-19,21-23H2,1-4H3;3H,2H2,1H3;1H

SMILES: CC1=C(C(c2cccc(c2)N(=O)=O)C(=C(C)N1)P1(=O)OCC(C)(C)CO1)C(=O)OCCN(Cc1ccccc1)c1ccccc1.CCO.Cl

Sinonimi:

• Hydrochloride
• Efonidipine hydrochloride ethanolate
• Efonidipine hydrochloride ethanol
• Efonidipine HCl ethanolate
• Ethanol, compd. with 2-(phenyl(phenylmethyl)amino)ethyl 5-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate P-oxide monohydrochloride (1:1)
• Ethanol, compd. with 2-(phenyl(phenylmethyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate monohydrochloride
• NZ 105 ethanolate
• Unii-3Br983K69O
• 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yl)-4-(3-nitrophenyl)-, 2-(phenyl(phenylmethyl)amino)ethyl ester, P-oxide, monohydrochloride
• 3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(phenyl(phenylmethyl)amino)ethyl ester, monohydrochloride, compd. with ethanol (1
• 1)
• 2-[Benzyl(Phenyl)Amino]Ethyl 5-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylate

2-(benzyl(phenyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate compound with ethanol (1:1) hydrochloride

CAS: 111011-76-8

Formula: C₃₆H₄₅ClN₃O₈P

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 714.1846

Ref: IN-DA0082Z5

2-(Benzyl(Phenyl)Amino)Ethyl 5-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylate Ethanol Hydrochloride

CAS: 111011-76-8

2-(Benzyl(Phenyl)Amino)Ethyl 5-(5,5-Dimethyl-2-Oxido-1,3,2-Dioxaphosphinan-2-Yl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylate Ethanol Hydrochloride

Purezza: 98%

Peso molecolare: 714.18g/mol

Ref: 54-OR1027315

Efonidipine hydrochloride monoethanolate

CAS: 111011-76-8

Efonidipine hydrochloride monoethanolate

Purezza: ≥98%

Peso molecolare: 714.18g/mol

Ref: 54-BUP06729

Efonidipine hydrochloride monoethanolate

CAS: 111011-76-8

Efonidipine HCl monoethanolate is a calcium blocker, boosts dehydroepiandrosterone sulfate in NCI-H295R cells.

Formula: C₃₆H₄₅ClN₃O₈P

Purezza: >99.99%

Colore e forma: Solid

Peso molecolare: 714.18

Ref: TM-T8401

Efonidipine Hydrochloride Monoethanolate

Prodotto controllato

CAS: 111011-76-8

Formula: C₃₄H₃₈N₃O₇P·C₂H₆O·ClH

Colore e forma: Neat

Peso molecolare: 714.185

Ref: TR-E436005

Efonidipine hydrochloride monoethanolate

CAS: 111011-76-8

Efonidipine hydrochloride monoethanolate is a calcium channel blocker that blocks voltage-dependent calcium channels. It has been shown to reduce the incidence of bowel disease in humans, and is used to treat high blood pressure and heart failure. Efonidipine hydrochloride monoethanolate can be administered orally, intravenously, or by injection. The drug has been shown to have an effect on the concentration–time curve of maternal blood glucose levels in pregnant women with diabetes mellitus type 1. Efonidipine hydrochloride monoethanolate also may cause drug interactions with other drugs that are metabolized by cytochrome P450 enzymes. It will bind to matrix proteins in atherosclerotic lesions and inhibit light-induced fluorescence. This drug can be used as an analytical tool for measuring concentrations of various substances in the body fluids of patients with metabolic disorders such as diabetes mellitus type 1 or 2, hyperlipidaemia, hypertension

Formula: C₃₆H₄₅ClN₃O₈P

Purezza: Min. 95%

Peso molecolare: 714.18 g/mol

Ref: 3D-BE179488