CAS 111119-28-9

glicina-arginina-glicina-acido aspartico-serina-prolina-lisina

Descrizione:

La sostanza chimica nota come "glicina-arginina-glicina-acido aspartico-serina-prolina-lisina" è un peptide composto da sei amminoacidi: glicina (Gly), arginina (Arg), acido aspartico (Asp), serina (Ser), prolina (Pro) e lisina (Lys). Questo peptide è spesso studiato per la sua attività biologica e le potenziali applicazioni in campi come la biochimica e la farmacologia. La sua sequenza suggerisce che potrebbe svolgere un ruolo nella segnalazione cellulare, in particolare nelle interazioni con le molecole di adesione cellulare e i recettori. La presenza di amminoacidi carichi positivamente come arginina e lisina può contribuire alla sua capacità di interagire con componenti cellulari caricati negativamente. Inoltre, la struttura del peptide può influenzare la sua solubilità, stabilità e funzione biologica complessiva. Il numero CAS 111119-28-9 identifica in modo univoco questo specifico peptide, facilitando il suo riconoscimento nella letteratura scientifica e nelle banche dati. In generale, glicina-arginina-glicina-acido aspartico-serina-prolina-lisina esemplifica la complessità delle interazioni peptidiche nei sistemi biologici e sottolinea l'importanza delle sequenze di amminoacidi nella determinazione della funzione.

Formula: C₂₈H₄₉N₁₁O₁₁

InChI: InChI=1/C28H49N11O11/c29-8-2-1-5-16(27(49)50)37-25(47)19-7-4-10-39(19)26(48)18(14-40)38-24(46)17(11-22(43)44)36-21(42)13-34-23(45)15(35-20(41)12-30)6-3-9-33-28(31)32/h15-19,40H,1-14,29-30H2,(H,34,45)(H,35,41)(H,36,42)(H,37,47)(H,38,46)(H,43,44)(H,49,50)(H4,31,32,33)/t15-,16-,17-,18-,19-/m0/s1

SMILES: C(CCN)C[C@@H](C(=O)O)N=C([C@@H]1CCCN1C(=O)[C@H](CO)N=C([C@H](CC(=O)O)N=C(CN=C([C@H](CCCNC(=N)N)N=C(CN)O)O)O)O)O

Sinonimi:

• H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH
• glycyl-N~5~-(diaminomethylidene)-L-ornithylglycyl-L-alpha-aspartyl-L-seryl-L-prolyl-L-lysine
• GRGDSPK
• GLY-ARG-GLY-ASP-SER-PRO-LYS
• EMD 56574
• Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC)
• L-Lysine, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-
• GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE
• GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE
• glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine

H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH

CAS: 111119-28-9

GRGDSPK, fibronectin analog.

Formula: C₂₈H₄₉N₁₁O₁₁

Purezza: 98.6%

Peso molecolare: 715.77

Ref: 01-4102088

Gly-Arg-Gly-Asp-Ser-Pro-Lys

CAS: 111119-28-9

Formula: C₂₈H₄₉N₁₁O₁₁

Peso molecolare: 715.76

Ref: 7W-GK2645

GRGDSPK

CAS: 111119-28-9

GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.

Formula: C₂₈H₄₉N₁₁O₁₁

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 715.76

Ref: TM-T7566

RGD Peptide GRGDSPK

CAS: 111119-28-9

GRGDSPK is the sequence found in cell binding region of fibronectin and many other proteins. The sequence, referred to as RGD, is critical for facilitating cell adhesion.-RGD peptide is an adhesive peptide which can be used in a biomaterial context to attach cells to a range of materials. RGD has many applications including as an antigen for integrin adhesion of thymocytes to thymic epithelial cells. RGD can be used as a blocking peptide to study bacteria and fibronectin. RGD can also be used on collagen-coated plates for study of integrins' role in progenitor cell differentiation. Delivery of RGD peptide inhibits bone mineralization in a dose-dependent manner so GRGDSPK is used to study the role of integrins in bone formation. The presence of RGD peptide dramatically alters bone morphology, with a disruption of osteoblast and mineralized matrix organisation. RGD is a vital research tool in bone formation and integrin.

Formula: C₂₈H₄₉N₁₁O₁₁

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 715.4 g/mol

Ref: 3D-CRB1000549

H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH

CAS: 111119-28-9

H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH is a peptide that has been shown to have chemotactic activity for monocytes and polymorphonuclear leucocytes, which are cells that participate in the inflammatory response. It also has biological properties that are reactive with hydroxyl groups and can be used to generate monoclonal antibodies. H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH has been shown to stimulate the migration of galleria mellonella larvae, suggesting it may have potential as an antiinflammatory agent.

Formula: C₂₈H₄₉N₁₁O₁₁

Purezza: Min. 95%

Peso molecolare: 715.76 g/mol

Ref: 3D-FG109749

H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH

CAS: 111119-28-9

GRGDSPK, fibronectin analog.

Formula: C₂₈H₄₉N₁₁O₁₁

Purezza: 98.7%

Peso molecolare: 715.77

Ref: 01-4011392