CAS 1112401-07-6

(2R)-2-(2,6-Dichlorophenoxy)-propanoic Acid Methyl Ester

Prodotto controllato

CAS: 1112401-07-6

Applications (2R)-2-(2,6-Dichlorophenoxy)-propanoic Acid Methyl Ester is an intermediate in the synthesis of (R)-Lofexidine (L469395), which is the R-enantiomer of Lofexidine. α2-Adrenoceptor agonist related structurally to Clonidine. Used in treatment of opioid withdrawal symptoms; antihypertensive.
References Velly, J., et al.: J. Pharmacol., 8, 351 (1977); Jarrot, B., et al.: Biochem. Pharmacol., 28, 141 (1979); Birch, P., at al.: Brit. J. Pharmacol., 68, 107 (1980)

Formula: C₁₀H₁₀Cl₂O₃

Colore e forma: Neat

Peso molecolare: 249.091

Ref: TR-D474678