CAS 1115-70-4

Cloridrato di metformina

Descrizione:

Cloridrato di metformina è un agente ipoglicemizzante orale utilizzato principalmente nella gestione del diabete mellito di tipo 2. Appartiene alla classe dei farmaci biguanidi e funziona diminuendo la produzione epatica di glucosio, migliorando la sensibilità all'insulina e migliorando l'assorbimento e l'utilizzo periferico del glucosio. La sostanza appare come una polvere cristallina bianca o bianco sporco, solubile in acqua ma con solubilità limitata nei solventi organici. La sua formula chimica è C4H11N5·HCl e ha un peso molecolare di circa 165,63 g/mol. Cloridrato di metformina è tipicamente somministrato in forma di compressa ed è noto per il suo profilo di sicurezza favorevole, con effetti collaterali gastrointestinali che sono i più comuni. È anche associato a un basso rischio di ipoglicemia quando usato da solo. Inoltre, la ricerca ha indicato potenziali benefici oltre al controllo glicemico, inclusa la protezione cardiovascolare e la gestione del peso. Come per qualsiasi farmaco, è essenziale utilizzare metformina sotto supervisione medica, considerando controindicazioni e potenziali interazioni con altri farmaci.

Formula: C₄H₁₁N₅·ClH

InChI: InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H

InChI key: InChIKey=OETHQSJEHLVLGH-UHFFFAOYSA-N

SMILES: C(NC(=N)N)(N(C)C)=N.Cl

Sinonimi:

• 1,1-Dimethylbiguanide Hydrochloride
• 3-(Diaminomethylidene)-1,1-Dimethylguanidine Hydrochloride (1:1)
• Apo-Metformin
• Apophage
• Benofomin
• Biguanide, 1,1-dimethyl-, hydrochloride
• Biguanide, 1,1-dimethyl-, monohydrochloride
• Dabex
• Denkaform
• Dextin
• Diabefagos
• Diabetmim
• Diabetmin
• Diabetosan
• Diabex
• Diaformin
• Dialon
• Diformin
• Diformin Retard
• Dimefor
• Fornidd
• Fortamet
• Geamet
• Glifage
• Glucaminol
• Glucofago
• Glucoform
• Glucoformin
• Glucomet
• Glucomin
• Glucomine
• Gluconil
• Glucophage
• Glucophage 850
• Glucophage Forte
• Glucophage Retard
• Glucophage SR
• Glucophage XR
• Glucophage-Mite
• Gludepatic
• Glufor
• Gluformin
• Glumeformin
• Glumetza
• Glumin
• Glumin XR
• Glupermin
• Glyceriphage
• Glyciphage
• Glycon
• Glyformin
• Imidodicarbonimidic diamide, N,N-dimethyl-, hydrochloride (1:1)
• Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride
• La 6023
• Meguan
• Melbin
• Metforal
• Metformin Hydrochloride
• Metgluco
• Metomin
• Miformin
• N,N-Dimethylbiguanide hydrochloride
• N,N-Dimethylbiguanidine monohydrochloride
• N,N-Dimethylbiguanidinium chloride
• N¹,N¹-Dimethylbiguanide hydrochloride
• Neodipa
• Obimat-SR
• Orabet
• Riomet
• Siamformet

Metformin Hydrochloride

CAS: 1115-70-4, 657-24-9

Formula: C₄H₁₁N₅·HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 165.63

Ref: 3B-M2009

1,1-Dimethylbiguanide hydrochloride

CAS: 1115-70-4

1,1-Dimethylbiguanide hydrochloride (HCl), or metformin HCl, 1115-70-4, is the salt form of the biguanide with antineoplastic and antihyperglycemic properties. Learn more.

Formula: C₄H₁₂ClN₅

Colore e forma: White, Crystalline powder

Peso molecolare: 165.63

Ref: 02-J63361

Metformin Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 1115-70-4

Colore e forma: Single Solution

Ref: 61-AMP0056.00-01

Metformin Hydrochloride

CAS: 1115-70-4

Colore e forma: White

Ref: 61-FOR0056.00

METFORMIN HYDROCHLORIDE CRS

CAS: 1115-70-4

METFORMIN HYDROCHLORIDE CRS

Formula: C₄H₁₂ClN₅

Colore e forma: Powder

Peso molecolare: 165.6246

Ref: 41-M0605000

Metformin for system suitability

CAS: 1115-70-4, 118632-64-7, 99-76-3

Metformin for system suitability

Colore e forma: White

Ref: 47-1296

Metformin hydrochloride

CAS: 1115-70-4

Metformin hydrochloride

Formula: C₄H₁₂ClN₅

Purezza: 100%

Colore e forma: White

Peso molecolare: 165.07812

Ref: 47-227

Metformin Hydrochloride

CAS: 1115-70-4

Non-aromatic imines and their derivatives; salts thereof, nesoi

Formula: C₄H₁₁N₅·HCl

Colore e forma: White Off-White Powder

Peso molecolare: 129.10145

Ref: 45-1396309

Metformin hydrochloride (mM/ml)

CAS: 1115-70-4

Formula: C₄H₁₂ClN₅

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 165.6246

Ref: IN-DA003RHI

Metformin hydrochloride

CAS: 1115-70-4

Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.

Formula: C₄H₁₂ClN₅

Purezza: 97.53% - 99.97%

Colore e forma: White Or Almost White Crystals Solid Crystalline

Peso molecolare: 165.63

Ref: TM-T0740

1,1-Dimethylbiguanide hydrochloride

CAS: 1115-70-4

1,1-Dimethylbiguanide hydrochloride

Formula: C₄H₁₁N₅·ClH

Purezza: 97%

Colore e forma: white solid

Peso molecolare: 165.62g/mol

Ref: 54-OR322044

Metformin hydrochloride, EP grade

CAS: 1115-70-4

Formula: C₄H₁₁N₅·HCl

Purezza: 98.5 - 101.0 % (dried substance)

Colore e forma: White or almost white crystals

Peso molecolare: 165.62

Ref: 7W-GP1221

Metformin HCl

CAS: 1115-70-4

Formula: C₄H₁₁N₅·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 129.17 36.46

Ref: 4Z-M-422

Metformin hydrochloride

CAS: 1115-70-4

Formula: C₄H₁₁N₅·HCl

Purezza: (Titration) 98.0 - 102.0 % (dried basis)

Colore e forma: White or almost white crystalline powder

Peso molecolare: 165.62

Ref: 7W-GP2747

Metformin hydrochloride

CAS: 1115-70-4

Metformin hydrochloride

Purezza: ≥95%

Peso molecolare: 165.63g/mol

Ref: 54-BUP17373

Metformin Hydrochloride

CAS: 1115-70-4

Formula: C₄H₁₁N₅·ClH

Colore e forma: Neat

Peso molecolare: 165.62

Ref: 04-C14956000

N1,N1-Dimethylbiguanide hydrochloride

CAS: 1115-70-4

Formula: C₄H₁₂ClN₅

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 165.63

Ref: 10-F463363

Metformin Hydrochloride

CAS: 1115-70-4

Formula: C₄H₁₁N₅·ClH

Colore e forma: Neat

Peso molecolare: 165.62

Ref: 86-MM0056.00

Metformin Impurity 13

CAS: 1115-70-4

Formula: C₄H₇N₅

Colore e forma: White To Off-White Solid

Peso molecolare: 125.14

Ref: 4Z-M-4226

Metformin Hydrochloride

Prodotto controllato

CAS: 1115-70-4

Applications An oral hypoglycemic agent. Slows electron transport in the oxidation pathway in mitochondria. Has been reported to reverse Lupus symptoms in mice in conjunction with 2-deoxy-d-glucose (D239000). Metformin is a well-known type 2 diabetes treatment. Research shows that metformin may inhibit tumor growth both directly and indirectly. Studies indicate that metformin modulates the biology of aging. Metformin blocks the conversion of select substrates into glucose in a redox-dependent manner.
References Tucker, G.T., et al.: Brit. J. Clin. Pharmacol., 12, 235 (1981), DeFronzo, R.A., et al.: N. Engl. J. Med., 333, 541 (1995); Chem. and Eng. News, page 7, Feb. 23 (2015); Nir Barzilai et al., Cell Metabolism 23: 1060 June 14 (2016); Chem. and Eng. News, page 7, Feb. 23 (2015); Chem. and Eng. News, page 12, July 30 (2018)

Formula: C₄H₁₁N₅·ClH

Colore e forma: White

Peso molecolare: 165.62

Ref: TR-M258815

Metformin Hydrochloride

CAS: 1115-70-4

Formula: C₄H₁₁N₅HCl

Peso molecolare: 129.17 : 36.46

Ref: ST-EA-CP-M3008

Metformin HCl - Bio-X ™

CAS: 1115-70-4

Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation.

Formula: C₄H₁₁N₅•HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 165.62 g/mol

Ref: 3D-BM164663

Metformin HCl

CAS: 1115-70-4

Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation.

Formula: C₄H₁₂ClN₅

Colore e forma: White Powder

Peso molecolare: 165.62 g/mol

Ref: 3D-FM25131