CAS 112811-59-3

Gatifloxacina

Descrizione:

Gatifloxacina è un antibiotico fluoroquinolone sintetico caratterizzato dalla sua attività antibatterica ad ampio spettro. Viene utilizzato principalmente per trattare varie infezioni batteriche, in particolare quelle che colpiscono le vie respiratorie e il sistema urinario. La struttura chimica di Gatifloxacina include un nucleo biciclico con un atomo di fluoro, che ne aumenta la potenza contro i batteri gram-positivi e gram-negativi. Presenta un meccanismo d'azione che comporta l'inibizione della girasi del DNA batterico e della topoisomerasi IV, enzimi critici per la replicazione e la riparazione del DNA. Gatifloxacina viene tipicamente somministrato per via orale ed è noto per la sua buona biodisponibilità. Tuttavia, è stato associato a potenziali effetti collaterali, tra cui disturbi gastrointestinali e, in rari casi, danni ai tendini. Il suo uso è diminuito in alcune regioni a causa di preoccupazioni per la sicurezza e l'emergere della resistenza batterica. Come per tutti gli antibiotici, è essenziale utilizzare Gatifloxacina in modo giudizioso per ridurre al minimo il rischio di sviluppo di resistenza e garantire la sua efficacia nel trattamento delle infezioni.

Formula: C₁₉H₂₂FN₃O₄

InChI: InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)

InChI key: InChIKey=XUBOMFCQGDBHNK-UHFFFAOYSA-N

SMILES: O(C)C1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N3CC(C)NCC3)C4CC4

Sinonimi:

• 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-(3-Methyl-1-Piperazinyl)-4-Oxo-3-Quinolinecarboxylic Acid
• 1-Cyclopropyl-6-Fluoro-8-Methoxy-7-(3-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
• 1-Cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
• 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
• 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-4-ium-1-yl)-4-oxoquinoline-3-carboxylate
• 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-
• Am 1155
• Bms 206584-01
• G-Cebran
• Gaity
• Gatiflo
• Gatifloxin
• Gatilox
• Gatiquin
• Gatispan
• Pd 135432
• Tequin
• Tymer
• Zymar

Gatifloxacin

CAS: 112811-59-3

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₁₉H₂₂FN₃O₄

Colore e forma: White Light Yellow Powder

Peso molecolare: 375.15943

Ref: 45-1288408

1-Cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylicacid

CAS: 112811-59-3

Formula: C₁₉H₂₂FN₃O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 375.3941

Ref: IN-DA001VAA

Gatifloxacin

CAS: 112811-59-3

Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.

Formula: C₁₉H₂₂FN₃O₄

Purezza: 99.50% - 99.85%

Colore e forma: White Powder

Peso molecolare: 375.39

Ref: TM-T1293

Gatifloxacin

CAS: 112811-59-3

Gatifloxacin

Purezza: ≥98%

Peso molecolare: 375.39g/mol

Ref: 54-BUP18589

Gatifloxacin

CAS: 112811-59-3

Formula: C₁₉H₂₂FN₃O₄

Colore e forma: White To Off-White Solid

Peso molecolare: 375.40

Ref: 4Z-G-344

Gatifloxacin

CAS: 112811-59-3

Formula: C₁₉H₂₂FN₃O₄

Colore e forma: Neat

Peso molecolare: 375.39

Ref: 04-C13998600

1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS: 112811-59-3

1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Purezza: 98%

Peso molecolare: 375.39g/mol

Ref: 54-PC1528

Gatifloxacin

Prodotto controllato

CAS: 112811-59-3

Applications An antibacterial.
References Bauernfeind, A.: J. Antimicro. Chemother., 40, 639 (1997), Fukuda, H., et al.: Antimicrob. Ag. Chemother., 42, 1917 (1998),

Formula: C₁₉H₂₂FN₃O₄

Colore e forma: White To Off-White

Peso molecolare: 375.39

Ref: TR-G250000

Gatifloxacin

CAS: 112811-59-3

Formula: C₁₉H₂₂FN₃O₄

Ref: TR-TRC-G250000

Gatifloxacin

CAS: 112811-59-3

Gatifloxacin is an antibiotic, which is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. Its source lies in its chemical synthesis, designed to inhibit bacterial enzymes necessary for DNA replication. The mode of action involves the inhibition of bacterial DNA gyrase and topoisomerase IV, which are critical enzymes for bacterial DNA replication, transcription, and repair. This dual inhibitory mechanism disrupts bacterial cell division and growth, leading to the eventual eradication of susceptible bacterial strains.

Formula: C₁₉H₂₂FN₃O₄

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 375.39 g/mol

Ref: 3D-AC23649

Gatifloxacin - Bio-X ™

CAS: 112811-59-3

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₉H₂₂FN₃O₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 375.39 g/mol

Ref: 3D-BG300001