CAS 113-52-0

Cloridrato di imipramina

Descrizione:

Il cloridrato di imipramina è un antidepressivo triciclico utilizzato principalmente nel trattamento del disturbo depressivo maggiore e di alcuni disturbi d'ansia. Funziona inibendo il riassorbimento dei neurotrasmettitori, in particolare norepinefrina e serotonina, aumentando così la loro disponibilità nella fessura sinaptica. Questo meccanismo contribuisce ai suoi effetti antidepressivi. La sostanza appare come una polvere cristallina bianca o bianco sporco ed è solubile in acqua, il che facilita la sua somministrazione in contesti clinici. Il cloridrato di imipramina ha una emivita relativamente lunga, consentendo una somministrazione una volta al giorno in molti casi. Gli effetti collaterali comuni possono includere secchezza delle fauci, sedazione, aumento di peso e potenziali effetti cardiovascolari, richiedendo un attento monitoraggio, specialmente nei pazienti con condizioni preesistenti. A causa del suo profilo farmacologico, è classificato come un farmaco da prescrizione e deve essere utilizzato sotto supervisione medica. Inoltre, è importante considerare le potenziali interazioni con altri farmaci, così come il rischio di sintomi da astinenza al momento della sospensione. In generale, il cloridrato di imipramina rimane un'opzione significativa nella farmacoterapia della depressione e dei disturbi correlati.

Formula: C₁₉H₂₅ClN₂

InChI: InChI=1/C20H25N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-11,20H,7,12-15H2,1-2H3;1H

InChI key: InChIKey=XZZXIYZZBJDEEP-UHFFFAOYSA-N

SMILES: C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl

Sinonimi:

• 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,N-dimethylpropan-1-aminium chloride
• 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
• 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepin hydrochloride
• 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
• 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, monohydrochloride
• Apo-Imipramine
• Censtim
• Censtin
• Chrytemin
• Deprinol
• Depsol
• Dimipressin
• Dipd
• Dyna-Zina
• Efuranol
• Eupramin
• Feinalmin
• G 22355
• Imavate
• Imidobenzyle
• Imidol
• Imilanyle
• Imipramina, Clorhidrato
• Imipramine hydrochloride
• Imipramine monohydrochloride
• Imipramine, chlorhydrate
• Imipraminhydrochlorid
• Imiprin
• Imizin
• Imizine
• Imizinum
• Impril
• Intalpram
• Iramil
• Irmin
• Janimine
• Melipramin
• Melipramine hydrochloride
• N-(3-Dimethylaminopropyl)iminodibenzyl hydrochloride
• N-(γ-Dimethylaminopropyl)iminodibenzyl hydrochloride
• Novo-pramine
• Praminil
• Presamine
• Promiben
• Pryleugan
• SK-Pramine
• Surplix
• Teperine
• Timolet
• Tipramine
• Tofranil
• Tofranile
• cocapimipramine25
• f)azepine,10,11-dihydro-5-(3-(dimethylamino)propyl)-5h-dibenz(hydrochlor
• chimoreptin
• f)azepine-5-propanamine,10,11-dihydro-n,n-dimethyl-5h-dibenz(monohydroch
• 10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
• f)azepine,5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(monohydrochloride
• IMIPRAMINE HCL
• f)azepine,5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(monohydrochl
• LABOTEST-BB LT00452014
• 10,11-Dihydro-N,N-dimithyl-5,H-dibenz[b,f]azepine-5-propanamine
• 5-(3-dimethylaminopropyl)-10,11-dihydro-5h-dibenz(b,f)azepinehydrochloride
• 10,11-dihydro-5-(3-(dimethylamino)propyl)-5h-dibenz[b,f]azepine hydrochloride
• 10,11-DIHYDRO-N,N-DIMETHYL-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
• antideprinhydrochloride

Imipramine Hydrochloride

CAS: 113-52-0, 50-49-7

Formula: C₁₉H₂₄N₂·HCl

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 316.87

Ref: 3B-I0971

Imipramine hydrochloride

CAS: 113-52-0

A serotonin uptake inhibitor

Formula: C₁₉H₂₅ClN₂

Colore e forma: White to off White Powder

Peso molecolare: 316.87

Ref: 02-J63723

Imipramine Hydrochloride

CAS: 113-52-0

Colore e forma: Neat

Ref: 61-FOR0077.00

Imipramine.HCl, 1mg/ml in Methanol (as free base)

CAS: 113-52-0

Colore e forma: Single Solution

Ref: LP-IMP-1066-HC-1LM

Imipramine.HCl

CAS: 113-52-0

Colore e forma: Neat

Ref: LP-IMP-1066-HC-10

Imipramine Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 113-52-0

Colore e forma: Single Solution

Ref: 61-AMP0077.00-01

Imipramine hydrochloride

CAS: 113-52-0

Imipramine hydrochloride

Formula: C₁₉H₂₅ClN₂

Purezza: 99.5%

Colore e forma: Off White

Peso molecolare: 316.17063

Ref: 47-932

IMIPRAMINE FOR SYSTEM SUITABILITY CRS

CAS: 113-52-0

IMIPRAMINE FOR SYSTEM SUITABILITY CRS

Formula: C₁₉H₂₅ClN₂

Peso molecolare: 316.8682

Ref: 41-Y0000893

IMIPRAMINE HYDROCHLORIDE CRS

CAS: 113-52-0

IMIPRAMINE HYDROCHLORIDE CRS

Formula: C₁₉H₂₅ClN₂

Colore e forma: Crystalline Powder. White. Light Yellow. Powder.

Peso molecolare: 316.8682

Ref: 41-I0100000

Imipramine Hydrochloride

CAS: 113-52-0

Clozapine; droperidol; and imipramine hydrochlorid

Formula: C₁₉H₂₄N₂·ClH

Colore e forma: White Powder

Peso molecolare: 316.17063

Ref: 45-1338007

Imipramine Hydrochloride

CAS: 113-52-0

Formula: C₁₉H₂₅ClN₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 316.8682

Ref: IN-DA0081OM

Imipramine HCl (Clomipramine HCl EP Impurity B HCl)

CAS: 113-52-0

Formula: C₁₉H₂₄N₂·HCl

Peso molecolare: 280.42 36.46

Ref: 4Z-I-016

Imipramine hydrochloride

CAS: 113-52-0

Imipramine hydrochloride

Purezza: ≥98%

Peso molecolare: 316.87g/mol

Ref: 54-BUP16484

Imipramine hydrochloride

CAS: 113-52-0

Formula: C₁₉H₂₄N₂·HCl

Purezza: ≥ 98.0%

Colore e forma: White to almost white powder to crystal

Peso molecolare: 316.87

Ref: 7W-GP6668

Imipramine Hydrochloride

CAS: 113-52-0

Imipramine Hydrochloride

Purezza: 98%

Peso molecolare: 316.87g/mol

Ref: 54-OR1029247

Imipramine hydrochloride

CAS: 113-52-0

Formula: C₁₉H₂₄N₂·ClH

Colore e forma: Neat

Peso molecolare: 316.87

Ref: 04-C14285950

Imipramine Hydrochloride

CAS: 113-52-0

Colore e forma: Neat

Ref: 86-MM0077.00

Imipramine hydrochloride

CAS: 113-52-0

Imipramine HCl: 1st-gen tricyclic antidepressant, inhibits serotonin and norepinephrine uptake, blocks aSMase, reduces MV/exosome secretion.

Formula: C₁₉H₂₅ClN₂

Purezza: 99.65% - 99.98%

Colore e forma: White To Off-White /Hydrochloride/ Un 1230 3/Pg 2

Peso molecolare: 316.87

Ref: TM-T7941

Imipramine Hydrochloride RS

CAS: 113-52-0

Colore e forma: White To Pale Yellow

Ref: 2K-1016000021

Imipramine hydrochloride

CAS: 113-52-0

Purezza: 95.0%

Peso molecolare: 316.8699951171875

Ref: 10-F053930

Imipramine Hydrochloride

CAS: 113-52-0

Applications Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters. Has little effect on the dopamine transporter.
References Wood, M.D., et al.: Neuropharmacology, 26, 1081 (1987), Casis, O., et al.: J. Cardiovasc. Pharmacol., 32, 521 (1998), Linner, L., et al.: Biol. Psychiatry, 46, 766 (1999), Teschemacher, et al.: Br. J. Pharmacol., 128, 479 (1999),

Formula: C₁₉H₂₄N₂·ClH

Colore e forma: Off White

Peso molecolare: 316.87

Ref: TR-I465980

Clomipramine EP Impurity B

CAS: 113-52-0

Formula: C₁₉H₂₄N₂HCl

Peso molecolare: 280.4 : 36.5

Ref: ST-EA-CP-C30002

Imipramine HCl - Bio-X ™

Prodotto controllato

CAS: 113-52-0

Imipramine is a drug that belongs to the class of tricyclic antidepressant drugs. It is used in the treatment of depression and childhood enuresis. It is a potent inhibitor of serotonin and norepinephrine reuptake. Imipramine blocks D-2 receptors, H1 receptors, α-1 and α-2 adrenergic receptors and muscarinic receptors. Also, it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.

Formula: C₁₉H₂₄N₂•HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 316.87 g/mol

Ref: 3D-BI164574

Imipramine hydrochloride

Prodotto controllato

CAS: 113-52-0

Imipramine hydrochloride is a hydrochloride salt form of imipramine, a surface active tricyclic drug, a potent inhibitor of serotonin and norepinephrine reuptake. It has a greater affinity for the serotonin and it has more anticholinergic side effects which can be helpful in treating enuresis. Imipramine blocks D-2 receptors, H1 receptors, alpha 1 and alpha 2 adrenergic receptors and muscarinic receptors. It is used for therapy of depression (major and bipolar) and nocturnal enuresis in children. Also it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.

Formula: C₁₉H₂₅ClN₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 316.87 g/mol

Ref: 3D-FI24561