CAS 113-52-0

Cloridrato di imipramina

Descrizione:

Il cloridrato di imipramina è un antidepressivo triciclico utilizzato principalmente nel trattamento del disturbo depressivo maggiore e di alcuni disturbi d'ansia. Funziona inibendo il riassorbimento dei neurotrasmettitori, in particolare norepinefrina e serotonina, aumentando così la loro disponibilità nella fessura sinaptica. Questo meccanismo contribuisce ai suoi effetti antidepressivi. La sostanza appare come una polvere cristallina bianca o bianco sporco ed è solubile in acqua, il che facilita la sua somministrazione in contesti clinici. Il cloridrato di imipramina ha una emivita relativamente lunga, consentendo una somministrazione una volta al giorno in molti casi. Gli effetti collaterali comuni possono includere secchezza delle fauci, sedazione, aumento di peso e potenziali effetti cardiovascolari, richiedendo un attento monitoraggio, specialmente nei pazienti con condizioni preesistenti. A causa del suo profilo farmacologico, è classificato come un farmaco da prescrizione e deve essere utilizzato sotto supervisione medica. Inoltre, è importante considerare le potenziali interazioni con altri farmaci, così come il rischio di sintomi da astinenza al momento della sospensione. In generale, il cloridrato di imipramina rimane un'opzione significativa nella farmacoterapia della depressione e dei disturbi correlati.

Formula: C₁₉H₂₅ClN₂

InChI: InChI=1/C20H25N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-11,20H,7,12-15H2,1-2H3;1H

InChI key: InChIKey=XZZXIYZZBJDEEP-UHFFFAOYSA-N

SMILES: C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl

Sinonimi:

• 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,N-dimethylpropan-1-aminium chloride
• 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
• 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepin hydrochloride
• 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
• 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, monohydrochloride
• Apo-Imipramine
• Censtim
• Censtin
• Chrytemin
• Deprinol
• Depsol
• Dimipressin
• Dipd
• Dyna-Zina
• Efuranol
• Eupramin
• Feinalmin
• G 22355
• Imavate
• Imidobenzyle
• Imidol
• Imilanyle
• Imipramina, Clorhidrato
• Imipramine hydrochloride
• Imipramine monohydrochloride
• Imipramine, chlorhydrate
• Imipraminhydrochlorid
• Imiprin
• Imizin
• Imizine
• Imizinum
• Impril
• Intalpram
• Iramil
• Irmin
• Janimine
• Melipramin
• Melipramine hydrochloride
• N-(3-Dimethylaminopropyl)iminodibenzyl hydrochloride
• N-(γ-Dimethylaminopropyl)iminodibenzyl hydrochloride
• Novo-pramine
• Praminil
• Presamine
• Promiben
• Pryleugan
• SK-Pramine
• Surplix
• Teperine
• Timolet
• Tipramine
• Tofranil
• Tofranile
• cocapimipramine25
• f)azepine,10,11-dihydro-5-(3-(dimethylamino)propyl)-5h-dibenz(hydrochlor
• chimoreptin
• f)azepine-5-propanamine,10,11-dihydro-n,n-dimethyl-5h-dibenz(monohydroch
• 10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
• f)azepine,5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(monohydrochloride
• IMIPRAMINE HCL
• f)azepine,5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(monohydrochl
• LABOTEST-BB LT00452014
• 10,11-Dihydro-N,N-dimithyl-5,H-dibenz[b,f]azepine-5-propanamine
• 5-(3-dimethylaminopropyl)-10,11-dihydro-5h-dibenz(b,f)azepinehydrochloride
• 10,11-dihydro-5-(3-(dimethylamino)propyl)-5h-dibenz[b,f]azepine hydrochloride
• 10,11-DIHYDRO-N,N-DIMETHYL-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
• antideprinhydrochloride

Imipramine Hydrochloride

CAS: 113-52-0

Applications Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters. Has little effect on the dopamine transporter.
References Wood, M.D., et al.: Neuropharmacology, 26, 1081 (1987), Casis, O., et al.: J. Cardiovasc. Pharmacol., 32, 521 (1998), Linner, L., et al.: Biol. Psychiatry, 46, 766 (1999), Teschemacher, et al.: Br. J. Pharmacol., 128, 479 (1999),

Formula: C₁₉H₂₄N₂·ClH

Colore e forma: Off White

Peso molecolare: 316.87

Ref: TR-I465980

Clomipramine EP Impurity B

CAS: 113-52-0

Formula: C₁₉H₂₄N₂HCl

Peso molecolare: 280.4 : 36.5

Ref: ST-EA-CP-C30002

Imipramine HCl - Bio-X ™

Prodotto controllato

CAS: 113-52-0

Imipramine is a drug that belongs to the class of tricyclic antidepressant drugs. It is used in the treatment of depression and childhood enuresis. It is a potent inhibitor of serotonin and norepinephrine reuptake. Imipramine blocks D-2 receptors, H1 receptors, α-1 and α-2 adrenergic receptors and muscarinic receptors. Also, it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.

Formula: C₁₉H₂₄N₂•HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 316.87 g/mol

Ref: 3D-BI164574

Imipramine hydrochloride

Prodotto controllato

CAS: 113-52-0

Imipramine hydrochloride is a hydrochloride salt form of imipramine, a surface active tricyclic drug, a potent inhibitor of serotonin and norepinephrine reuptake. It has a greater affinity for the serotonin and it has more anticholinergic side effects which can be helpful in treating enuresis. Imipramine blocks D-2 receptors, H1 receptors, alpha 1 and alpha 2 adrenergic receptors and muscarinic receptors. It is used for therapy of depression (major and bipolar) and nocturnal enuresis in children. Also it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.

Formula: C₁₉H₂₅ClN₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 316.87 g/mol

Ref: 3D-FI24561