CAS 113-80-4

argiprestocina

Descrizione:

argiprestocina, con il numero CAS 113-80-4, è un peptide sintetico che agisce come vasodilatatore ed è utilizzato principalmente in contesti di ricerca. È noto per la sua capacità di imitare l'azione di alcuni peptidi endogeni, influenzando il rilassamento della muscolatura liscia vascolare e potenzialmente impattando la dinamica del flusso sanguigno. La sostanza è caratterizzata dalla sua specifica sequenza di amminoacidi, che contribuisce alla sua attività biologica. argiprestocina è spesso studiato per i suoi effetti sulla funzione cardiovascolare e le sue potenziali applicazioni terapeutiche in condizioni legate alla salute vascolare. Come peptide, è tipicamente solubile in soluzioni acquose e potrebbe richiedere una manipolazione attenta per mantenere la sua stabilità. Il suo profilo farmacologico include interazioni con recettori specifici, portando a varie risposte fisiologiche. Tuttavia, le informazioni dettagliate riguardanti la sua sicurezza, efficacia e applicazioni cliniche sono limitate, poiché è utilizzato principalmente in contesti sperimentali piuttosto che in un uso clinico diffuso.

Formula: C₄₃H₆₇N₁₅O₁₂S₂

InChI: InChI=1/C43H67N15O12S2/c1-3-21(2)34-41(69)53-26(12-13-31(45)60)37(65)55-28(17-32(46)61)38(66)56-29(20-72-71-19-24(44)35(63)54-27(39(67)57-34)16-22-8-10-23(59)11-9-22)42(70)58-15-5-7-30(58)40(68)52-25(6-4-14-50-43(48)49)36(64)51-18-33(47)62/h8-11,21,24-30,34,59H,3-7,12-20,44H2,1-2H3,(H2,45,60)(H2,46,61)(H2,47,62)(H,51,64)(H,52,68)(H,53,69)(H,54,63)(H,55,65)(H,56,66)(H,57,67)(H4,48,49,50)/t21-,24-,25-,26-,27-,28-,29-,30-,34-/m0/s1

SMILES: CC[C@H](C)[C@H]1C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CC(=N)O)C(=N[C@@H](CSSC[C@@H](C(=N[C@@H](Cc2ccc(cc2)O)C(=N1)O)O)N)C(=O)N1CCC[C@H]1C(=N[C@@H](CCCNC(=N)N)C(=NCC(=N)O)O)O)O)O)O

Sinonimi:

• Argiprestocin [INN]
• (Arg(sup 8))oxytocin
• 8-Arg-vasotocin
• 8-Arginine vasotocin
• 8-L-Arginineoxytocin
• Arg-vasotocin
• Arginine vasotocin
• Argiprestocina
• Argiprestocina [INN-Spanish]
• Argiprestocine
• Argiprestocine [INN-French]
• Argiprestocinum
• Argiprestocinum [INN-Latin]
• Brn 4902334
• Natriuretic hormone (ox pineal)
• Unii-W6S6Ury8Of
• 8-Arginineoxytocin
• Oxytocin, 8-L-arginine-
• 1-{[(4R,7S,10S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}prolyl-N~5~-(diaminomethylidene)-L-ornithylglycinamide
• 1-{[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-N~5~-(diaminomethylidene)-L-ornithylglycinamide
• Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-Nh2
• Argiprestocin
• 8-l-arginine-oxytoci
• [ARG8]-VASOTOCIN
• H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2, (Disulfide bond)
• CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2 USP/EP/BP
• H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2, CYS1,6, CYCLIC
• CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2(DISULFIDE BRIDGE:CYS1-CYS6)
• 8-argininevasotocin
• 1-[(1R,4S,7S,13S,16R)-16-amino-4-(2-amino-2-oxoethyl)-7-(3-amino-3-oxopropyl)-10-[(2S)-butan-2-yl]-13-[(4-hydroxyphenyl)methyl]-3,6,9,12,15-pentaoxo-18,19-dithia-2,5,8,11,14-pentazacycloicosane-1-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
• 1-[[(1R,4S,7S,13S,16R)-16-azanyl-4-(2-azanyl-2-oxo-ethyl)-7-(3-azanyl-3-oxo-propyl)-10-[(2S)-butan-2-yl]-13-[(4-hydroxyphenyl)methyl]-3,6,9,12,15-pentaoxo-18,19-dithia-2,5,8,11,14-pentazacycloicos-1-yl]carbonyl]-N-[(2S)-1-[(2-azanyl-2-oxo-ethyl)amino]-5-[bis(azanyl)methylideneamino]-1-oxo-pentan-2-yl]pyrrolidine-2-carboxamide
• 1-[(1R,4S,7S,13S,16R)-16-amino-4-(2-amino-2-keto-ethyl)-7-(3-amino-3-keto-propyl)-13-(4-hydroxybenzyl)-3,6,9,12,15-pentaketo-10-[(1S)-1-methylpropyl]-18,19-dithia-2,5,8,11,14-pentazacycloicosane-1-carbonyl]-N-[(1S)-1-[(2-amino-2-keto-ethyl)carbamoyl]-4-guanidino-butyl]pyrrolidine-2-carboxamide
• [ARG8]-VASOTOCIN (FROG, CHICKEN)
• VASOTOCIN ARG 8
• (arg(sup8))oxytocin
• [Arg8]-Vasotocin trifluoroacetate
• H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Cys1-Cys6)
• VASOTOCIN, [ASU16,ARG8]
• CYIQNCPRG-NH2
• H-CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2

(Arg⁸)-Vasotocin (Salt form acetate)

CAS: 113-80-4

Non-mammalian Arg-vasopressin/oxytocin analog.

Formula: C₄₃H₆₇N₁₅O₁₂S₂

Purezza: 98.7%

Colore e forma: White Whitish Powder

Peso molecolare: 1050.23

Ref: 01-4100576

(Arg⁸)-Vasotocin (Salt form trifluoroacetate)

CAS: 113-80-4

Vasotocin (AVT, argiprestocin) is the vasopressin/oxytocin analog produced in birds, amphibians and fish. AVT shows antidiuretic as well as reproductive activities.

Formula: C₄₃H₆₇N₁₅O₁₂S₂

Purezza: 98.0%

Colore e forma: White

Peso molecolare: 1050.23

Ref: 01-4031338

[Arg8]-Vasotocin

CAS: 113-80-4

[Arg8]-Vasotocin is a hormone present in the neurohypophysis of nonmammalian vertebrates that is related to vasopressin and oxytocin.

Formula: C₄₃H₆₇N₁₅O₁₂S₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1050.22

Ref: TM-TP1400

[Arg8]-Vasotocin trifluoroacetate

CAS: 113-80-4

Vasotocin is a peptide hormone that regulates a variety of physiological processes, including blood pressure, water permeability, and locomotor activity. Vasotocin is synthesized from the precursor arginine vasotocin (AVT) by the enzyme polypeptide chain elongation. AVT can bind to two different receptors: one that is inhibitory and one that is excitatory. The inhibitory receptor for AVT can be activated by vasopressin or oxytocin, while the excitatory receptor for AVT can be activated by atrial natriuretic peptide. Activation of both receptors leads to increased blood flow and decreased blood pressure. Vasotocin has been shown to have an inhibitory effect on the polymerase chain reaction in human serum and to have a model system in rats.

Formula: C₄₃H₆₇N₁₅O₁₂S₂

Purezza: Min. 95%

Peso molecolare: 1,050.22 g/mol

Ref: 3D-FA73663