CAS 1138-80-3

N-Carbobenzoilossiglicina

Descrizione:

N-Carbobenzoilossiglicina, noto anche come Cbz-Gly, è un derivato aminoacidico caratterizzato dalla presenza di un gruppo protettivo carbobenzyloxy (Cbz) attaccato al gruppo amminico della glicina. Questo composto appare tipicamente come un solido cristallino bianco a bianco sporco ed è solubile in solventi organici come metanolo e diclorometano, ma meno solubile in acqua. Il gruppo Cbz funge da moiety protettivo, rendendo N-Carbobenzoilossiglicina utile nella sintesi peptidica, poiché può essere rimosso selettivamente in condizioni specifiche per ottenere l'aminoacido libero. Il composto è spesso utilizzato nella sintesi organica e nella chimica medicinale, in particolare nello sviluppo di farmaci a base di peptidi. La sua struttura molecolare include uno scheletro di glicina, che contribuisce al suo ruolo nei sistemi biologici, e il gruppo Cbz ne migliora la stabilità e reattività in varie reazioni chimiche. Come per molte sostanze chimiche, la corretta manipolazione e le precauzioni di sicurezza sono essenziali a causa dei potenziali pericoli associati al suo uso.

Formula: C₁₀H₁₁NO₄

InChI: InChI=1/C10H11NO4/c12-9(13)6-11-10(14)15-7-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)/p-1

InChI key: InChIKey=CJUMAFVKTCBCJK-UHFFFAOYSA-N

SMILES: C(OC(NCC(O)=O)=O)C1=CC=CC=C1

Sinonimi:

• (Carbobenzoxy)glycine
• (Carbobenzyloxy)glycine
• 2-(Benzyloxycarbonylamino)acetic acid
• 2-(Phenylmethoxycarbonylamino)acetic acid
• Benzyloxycarbonylglycine
• Cbz-Gly-OH
• Cbz-glycine
• Glycine, N-[(phenylmethoxy)carbonyl]-
• Glycine, N-carboxy-, N-benzyl ester
• N-(Benzyloxycarbonyl)glycine
• N-(Carbobenzoxy)glycine
• N-(Carbobenzyloxy)glycine
• N-(α-Carbobenzoxy)glycine
• N-Benzyloxycarbonylglycin
• N-Benzyloxycarbonylglycine
• N-CBZ-Glycine N-Carbobenzyloxy-glycine
• N-Carboxyglycine N-benzyl ester
• N-Cbz-Gly-OH
• N-Cbz-glycine
• N-[(Phenylmethoxy)carbonyl]glycine
• N-[(benzyloxy)carbonyl]glycine{[(benzyloxy)carbonyl]amino}acetate
• N-benciloxicarbonilglicina
• N-cbz-glycine crystalline
• N^α-(Benzyloxycarbonyl)glycine
• Nsc 2526
• Nα-(Benzyloxycarbonyl)glycine
• Z-Gly-OH
• Z-glycine
• [[(Benzyloxy)carbonyl]amino]acetic acid
• z-Gly
• RARECHEM AL BO 0395
• N-CARBOBENZOXYGLYCINE
• Z-L-GLYCINE
• CBZ-GLY
• CARBOBENZYLOXYGLYCINE
• N-ALPHA-BENZYLOXYCARBONYL-GLYCINE
• N-CBZ-GLYCINE-OH
• N-ALPHA-CBZ-GLYCINE
• N-ALPHA-CARBOBENZOXY-GLYCINE
• 2-([(BENZYLOXY)CARBONYL]AMINO)ACETIC ACID
• LABOTEST-BB LT00005891
• BENZYLOXYCARBONYL-GLYCINE
• TIMTEC-BB SBB003458

N-Carbobenzoxyglycine

CAS: 1138-80-3

Formula: C₁₀H₁₁NO₄

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 209.20

Ref: 3B-C0575

N-Benzyloxycarbonylglycine, 98+%

CAS: 1138-80-3

N-Carbobenzoxyglycine is used in the dipeptide synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has n

Formula: C₁₀H₁₁NO₄

Purezza: 98+%

Colore e forma: Crystals or powder or crystalline powder, White

Peso molecolare: 209.20

Ref: 02-A15928

Z-Gly-OH

CAS: 1138-80-3

Bachem ID: 4000228.

Formula: C₁₀H₁₁NO₄

Purezza: 98.8%

Colore e forma: White

Peso molecolare: 209.2

Ref: 01-4000228

Glycine, N-[(phenylmethoxy)carbonyl]-

CAS: 1138-80-3

Formula: C₁₀H₁₁NO₄

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 209.1986

Ref: IN-DA0009QA

Z-Gly-OH

CAS: 1138-80-3

Formula: C₁₀H₁₁NO₄

Peso molecolare: 209.20

Ref: 7W-GM7548

Z-Glycine, 10mM (in DMSO)

CAS: 1138-80-3

Z-Glycine, 10mM (in DMSO)

Purezza: ≥98%

Peso molecolare: 209.2g/mol

Ref: 54-BUP19004

Z-Glycine

CAS: 1138-80-3

N-Benzyloxycarbonylglycine is a lipid-like drug designed for enhanced brain penetration.

Formula: C₁₀H₁₁NO₄

Purezza: 99.88%

Colore e forma: Slightly Beige Powder

Peso molecolare: 209.2

Ref: TM-T33604

Z-Glycine

CAS: 1138-80-3

Z-Glycine

Purezza: 98%

Peso molecolare: 209.20g/mol

Ref: 54-BIZ0428

N-Carbobenzoxyglycine

CAS: 1138-80-3

Applications N-Carbobenzoxyglycine is used in the dipeptide synthesis.
References Hans, D., et al.: Med. Chem., 2, 627 (2006), Guzman, F., et al.: J. Biotechnol., 10, 279 (2007), Vlieghe, P., et al.: Drug Discov. Today, 15, 40 (2010),

Formula: C₁₀H₁₁NO₄

Colore e forma: Neat

Peso molecolare: 209.2

Ref: TR-C175995

Cbz-glycine

CAS: 1138-80-3

Cbz-glycine is a hydrogen bond donor that can react with trifluoroacetic acid in a one-step reaction to form an ester hydrochloride. It is used in the synthesis of monoclonal antibodies and has been shown to inhibit the growth of receptor cells. Cbz-glycine reacts with protocatechuic acid, pyrazinoic acid, and ester hydrochloride to form pharmacokinetic properties. It has been shown to have pharmacokinetic properties by inhibiting prostaglandin synthesis.

Formula: C₁₀H₁₁NO₄

Purezza: Min. 95%

Peso molecolare: 209.2 g/mol

Ref: 3D-FC39362

Z-Gly-OH

CAS: 1138-80-3

M03051 - Z-Gly-OH

Formula: C₁₀H₁₁NO₄

Purezza: 95%

Colore e forma: Solid, White to off-white crystalline powder

Peso molecolare: 209.201

Ref: 10-M03051

Z-Glycine extrapure, 99%

CAS: 1138-80-3

Formula: C₁₀H₁₁NO₄

Purezza: min. 99 %

Colore e forma: White, Crystalline powder

Peso molecolare: 209.2

Ref: SR-86632

N-Carbobenzoxyglycine

CAS: 1138-80-3

Formula: C₁₀H₁₁NO₄

Peso molecolare: 209.2

Ref: ST-EA-CP-E12036