CAS 114-25-0

Biliverdina

Descrizione:

Biliverdina è un pigmento biliare tetrapirrolico verde che è un prodotto della degradazione dell'eme, formato principalmente dalla decomposizione dell'emoglobina. È caratterizzato dal suo colore verde, che è dovuto al suo sistema di doppi legami coniugati, che gli consente di assorbire luce nello spettro visibile. Biliverdina è solubile in acqua e ha una formula molecolare di C33H34N4O6, con un peso molecolare di circa 582,6 g/mol. Svolge un ruolo significativo in vari processi biologici, inclusa l'azione come antiossidante e la partecipazione alla regolazione delle funzioni cellulari. Biliverdina è anche un precursore della bilirubina, un altro importante pigmento biliare. In termini di stabilità, Biliverdina può essere sensibile alla luce e ai cambiamenti di pH, il che può influenzare la sua struttura e reattività. La sua presenza nei sistemi biologici è spesso associata alla funzione epatica e può essere indicativa di determinate condizioni mediche quando trovata in concentrazioni anormali. In generale, Biliverdina è un composto importante in biochimica e medicina, riflettendo i complessi processi del metabolismo dell'eme.

Formula: C₃₃H₃₄N₄O₆

InChI: InChI=1/C33H34N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-15,35H,1-2,9-12H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-,28-15-

InChI key: InChIKey=QBUVFDKTZJNUPP-BBROENKCSA-N

SMILES: C(\C1=C(CCC(O)=O)C(C)=C(/C=C\2/C(C=C)=C(C)C(=O)N2)N1)=C3/C(CCC(O)=O)=C(C)C(/C=C\4/C(C)=C(C=C)C(=O)N4)=N3

Sinonimi:

• 21H-Biline-8,12-dipropanoic acid, 3,18-diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-
• 3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid
• 3-[(2Z)-2-[[3-(2-carboxyethyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl]methylene]-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-pyrrol-2-ylidene)methyl]pyrrol-3-yl]propanoic acid
• 3-[2-[(E)-[(5E)-3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(E)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[(Z)-[(5E)-3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[(Z)-[(5Z)-3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[[3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• Biline-8,12-dipropionic acid, 1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-
• Biline-8,12-dipropionic acid, 1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl- (8CI)
• Biliverdin IXalpha
• Biliverdin IXα
• Biliverdina
• Biliverdine
• Biliverdine (VAN)
• Biliverdine dihydrochloride
• Dehydrobilirubin
• Nsc 62793
• Oocyan
• Protobiliverdin IXα
• Pyrrole-3-propionic acid, 2-[[3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-3-pyrrolin-2-ylidene)methyl]-2H-pyrrol-2-ylidene]methyl]-4-methyl-5-[(4-methyl-5-oxo-3-vinyl-3-pyrrolin-2-ylidene)methyl]-
• Uteroverdine
• α-Biliverdin
• Biliverdin
• 3-[2-[(Z)-[(5E)-3-(2-carboxyethyl)-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-yl)methylidene]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[(E)-[(5E)-3-(2-carboxyethyl)-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-yl)methylidene]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(E)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
• ocyan
• 3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetrametyl-1,19-dioxo-21H-biline-8,12-dipropanoic Acid

3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid

CAS: 114-25-0

Formula: C₃₃H₃₄N₄O₆

Purezza: 70%

Colore e forma: Solid

Peso molecolare: 582.6463

Ref: IN-DA0038B8

Biliverdine

CAS: 114-25-0

Stability Light Sensitive
Applications Biliverdine is a precursor of Bilirubin. Biliverdine is formed in the body from hemoglobin. The bile of amphibians and of birds contains Biliverdine only. It is also an inhibitor for hepatitis C virus.
References Lemberg et al.: Biochem. J., 35, 363 (1941); Gutierrez-Grobe, Y. et al.: Annals. Hepatol., 10, 105 (2011);

Formula: C₃₃H₃₄N₄O₆

Colore e forma: Dark Green To Black

Peso molecolare: 582.65

Ref: TR-B386400

Biliverdine-d4 (Major, may contain up to 3% d0) (Technical Grade)

Prodotto controllato

CAS: 114-25-0

Applications Labelled Biliverdine is a precursor of Bilirubin. Biliverdine is formed in the body from hemoglobin. The bile of amphibians and of birds contains Biliverdine only. It is also an inhibitor for hepatitis C virus.
References Lemberg et al.: Biochem. J., 35, 363 (1941); Gutierrez-Grobe, Y. et al.: Annals. Hepatol., 10, 105 (2011);

Formula: C₃₃H₃₀D₄N₄O₆

Purezza: >90%

Colore e forma: Neat

Peso molecolare: 586.67

Ref: TR-B386402

Biliverdine

CAS: 114-25-0

Biliverdine is a fluorescent probe that selectively binds to bilirubin and other hydroxycinnamic acids in tissue. Biliverdine can be used to measure the oxidative injury of tissues as well as the activity of enzymes involved in the metabolism of these compounds. The use of biliverdin with other fluorescent probes has been shown to improve the sensitivity and specificity for detecting oxidative injury. Biliverdin has also been shown to have anti-inflammatory properties, which may be due to its ability to inhibit the production of growth factor-β1 and 4-hydroxycinnamic acid.

Formula: C₃₃H₃₄N₄O₆

Purezza: Min. 70 Area-%

Colore e forma: Green Powder

Peso molecolare: 582.65 g/mol

Ref: 3D-FB18596

Biliverdin

CAS: 114-25-0

Biliverdin, produced through the oxidation of bilirubin, can also be synthesized through a non-protoporphyrin pathway in Corynebacterium glutamicum [1].

Formula: C₃₃H₃₄N₄O₆

Colore e forma: Solid

Peso molecolare: 582.65

Ref: TM-T84736