CAS 114-49-8

Bromidrato di scopolamina

Descrizione:

Bromidrato di scopolamina è un alcaloide tropano derivato da piante della famiglia Solanaceae, in particolare dalla pianta della belladonna. È una polvere cristallina bianca o bianco sporco che è solubile in acqua e alcol, rendendola adatta per varie formulazioni farmaceutiche. La sostanza agisce principalmente come un agente anticolinergico, bloccando l'azione dell'acetilcolina nel sistema nervoso, il che la rende efficace nel trattamento della cinetosi, nausea e vomito. Bromidrato di scopolamina è anche utilizzato in contesti preoperatori per ridurre la salivazione e le secrezioni. I suoi effetti farmacologici includono sedazione, amnesia e rilassamento muscolare, ma può anche causare effetti collaterali come secchezza delle fauci, visione offuscata e sonnolenza. A causa del suo potenziale di abuso e del rischio di effetti collaterali gravi, il suo uso è attentamente monitorato in contesti clinici. Come per qualsiasi farmaco, è essenziale utilizzare Bromidrato di scopolamina sotto la guida di un professionista sanitario per garantire sicurezza ed efficacia.

Formula: C₁₇H₂₂BrNO₄

InChI: InChI=1/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13+,14?,15-,16?;/m1./s1

InChI key: InChIKey=WTGQALLALWYDJH-MOUKNHLCSA-N

SMILES: CN1[C@@]2([C@]3([C@](O3)([C@]1(C[C@@H](OC([C@H](CO)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H].Br

Sinonimi:

• (-)-Scopolamine bromide
• (-)-Scopolamine, HBr
• (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl 3-hydroxy-2-phenylpropanoate hydrobromide (1:1)
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, 6β,7β-epoxy-, (-)-tropate (ester), hydrobromide
• 3-Oxa-9-azatricyclo[3.3.1.0^2,4]nonane, benzeneacetic acid deriv.
• 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrobromide (1:1)
• 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrochloride
• Beldavrin
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide (1:1), (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide, (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide, [7(S)-(1α,2β,4β,5α,7β)]-
• Euscopol
• Hydroscine hydrobromide
• Hyocine f hydrobromide
• Hyoscine Hydrobromide
• Hyoscine bromide
• Hysco
• Isoscopil
• Kwells
• Scopamin
• Scopolamine hydrobromide
• Scopolaminium bromide
• Scopolammonium bromide
• Scopos
• Sea Legs
• Sereen
• Triptone
• Wellcome Brand Scopolamine hydrobromide Injection
• benzeneacetic acid, alpha-(hydroxymethyl)-, bromide, (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl ester, (alphaS)-
• l-Hyoscine hydrobromide
• l-Scopolamine hydrobromide
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide (1:1), (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide, [7(S)-(1α,2β,4β,5α,7β)]-
• Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide, (αS)-
• scopolamine hydrobromide trihydrate
• 1αH,5αH-Tropan-3α-ol, 6β,7β-epoxy-, (-)-tropate (ester), hydrobromide
• HYOSCINE
• ),hydrobromide
• (A,S)-ALPHA-(HYDROXYMETHYL)BENZENEACETIC ACID (1A,2B,4B,5A,7B)-9-METHYL-3-OXA-9-AZATRICYCLO[3.3.1.02,4]NON-7-YL ESTER HYDROBROMIDE
• alpha-(hydroxymethyl)-benzeneaceticaci9-methyl-3-oxa-9-azatricyclo[3.3.1.
• SCOPINE TROPATE HYDROBROMIDE
• HYOSCINE HBR
• SCOPOLOAMINE HYDROBROMIDE
• .alpha.-(hydroxymethyl)-,9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-ylester,hydrobromide,[7(Benzeneaceticacid
• hydroscinehydrobromide
• ATROSCINE HYDROBROMIDE
• hyocinefhydrobromide
• 5-alpha-h-tropan-3-alpha-ol,6-beta,7-beta-epoxy-1-alpha-(-)-tropate(ester
• (-)-scopolaminebromide

Scopolamine HBr (Hyoscine HBr)

CAS: 114-49-8

Formula: C₁₇H₂₁NO₄·HBr

Colore e forma: White To Off-White Solid

Peso molecolare: 303.36 80.91

Ref: 4Z-S-012

Scopolamine hydrobromide

CAS: 114-49-8

Formula: C₁₇H₂₂BrNO₄

Purezza: 95%~99%

Peso molecolare: 384.27

Ref: BP-BP1274

Scopolamine Hydrobromide Trihydrate

CAS: 114-49-8, 51-34-3, 6533-68-2

Formula: C₁₇H₂₁NO₄·HBr·3H₂O

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 438.32

Ref: 3B-S0021

(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide

CAS: 114-49-8

(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide

Purezza: ≥95%

Peso molecolare: 438.31g/mol

Ref: 54-OR310495

Scopolamine hydrobromide

CAS: 114-49-8

Natural alkaloid

Formula: C₁₇H₂₁NO₄HBr

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 384.27

Ref: 5G-80046

Scopolamine Hydrobromide Hydrate

Prodotto controllato

CAS: 114-49-8, 6533-68-2

Applications Scopolamine Hydrobromide Hydrate is an acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Neuroprotective & Neuroresearch Product.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brand, J.J., et al.: Lancet, 2, 232 (1970); Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979); Clissold, S.P., et al.: Drugs, 29, 189 (1985); Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990);

Formula: C₁₇H₂₁NO₄·HBr·xH₂O

Colore e forma: White Solid

Peso molecolare: 384.26

Ref: TR-S200000

Scopolamine-13C, D3 Hydrobromide

Prodotto controllato

CAS: 114-49-8

Applications Scopolamine-13C, d3 Hydrobromide, is the labeled analogue of Scopolamine-d3 Hydrobromide (S200002), an acetylcholine antagonist, used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),

Formula: C₁₆₁₃CH₁₉D₃BrNO₄

Colore e forma: Off-White

Peso molecolare: 388.28

Ref: TR-S200003

Scopolamine hydrobromide

CAS: 114-49-8

Scopolamine hydrobromide is an anticholinergic medication, which is a derivative of tropane alkaloids sourced primarily from Solanaceae family plants, such as Hyoscyamus niger and Datura stramonium. Its mode of action involves competitive inhibition of acetylcholine at muscarinic receptors in the central and peripheral nervous systems. This blocking effect impedes parasympathetic nerve impulses, leading to diminished activity in smooth muscles and glandular secretions.

Formula: C₁₇H₂₁NO₄·HBr

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 384.26 g/mol

Ref: 3D-FA66263