CAS 114056-26-7

vasotocina, (acido beta-mercapto-beta,beta-ciclopentametilenopropionico)-O-metil-Tyr(2)-Thr(4)-Orn(8)-Tyr(9)-NH2

Descrizione:

La vasotocina è un ormone peptidico che svolge un ruolo significativo in vari processi fisiologici, in particolare nella regolazione dell'equilibrio idrico e della pressione sanguigna. È strutturalmente correlata alla vasopressina e all'ossitocina, presentando una struttura ciclica che ne migliora la stabilità e l'attività biologica. La sequenza specifica di amminoacidi nella vasotocina include modifiche come l'acido beta-mercapto-beta,beta-ciclopentametilenopropionico, che contribuisce alle sue proprietà uniche. Questo composto mostra una forte affinità per i recettori della vasopressina, influenzando la funzione renale e il tono vascolare. Inoltre, la vasotocina è coinvolta nei comportamenti sociali e nelle risposte allo stress in alcune specie. Il suo numero CAS, 114056-26-7, la identifica in modo univoco nei database chimici, facilitando la ricerca e l'applicazione in farmacologia e biochimica. La presenza di residui specifici di amminoacidi, come O-metil-Tyr e Orn, indica un potenziale per interazioni varie all'interno dei sistemi biologici, rendendola un argomento di interesse negli studi relativi alla neuroendocrinologia e allo sviluppo terapeutico. In generale, le caratteristiche della vasotocina sottolineano la sua importanza nelle scienze biologiche di base e applicate.

Formula: C₅₄H₇₉N₁₁O₁₃S₂

InChI: InChI=1/C54H79N11O13S2/c1-5-30(2)44(63-49(73)38(26-32-13-17-34(67)18-14-32)58-43(69)28-54(80)21-7-6-8-22-54)51(75)64-45(31(3)66)52(76)61-39(27-42(56)68)48(72)62-40(29-79)53(77)65-24-10-12-41(65)50(74)59-36(11-9-23-55)47(71)60-37(46(57)70)25-33-15-19-35(78-4)20-16-33/h13-20,29-31,36-41,44-45,66-67,80H,5-12,21-28,55H2,1-4H3,(H2,56,68)(H2,57,70)(H,58,69)(H,59,74)(H,60,71)(H,61,76)(H,62,72)(H,63,73)(H,64,75)/t30-,31+,36-,37-,38-,39-,40-,41-,44-,45-/m0/s1

Sinonimi:

• 1-d(CH2)5-2-(O-Methyl)-tyrosyl-4-theonyl-8-ornithyl-9-tyrosinamide-vasotocin
• N-((1-Mercaptocyclohexyl)acetyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-L-tyrosinamide cyclic (1-5)-disulfide
• Ovta
• Ota-vasotocin
• d(CH2)5-O-Methyl-tyrosyl(2)-threonyl(4)-ornithyl(8)-tyrosinamide(9)-vasotocin
• d(CH2)5-Tyr(Me)(2)-thr(4)-orn(8)-tyr(9)-NH2-vasotocin
• L-Tyrosinamide, N-((1-mercaptocyclohexyl)acetyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-, cyclic (1-5)-disulfide
• N-[(1-sulfanylcyclohexyl)acetyl]-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-3-thioxo-L-alanyl-L-prolyl-L-ornithyl-O-methyl-L-tyrosinamide
• Vasotocin, (beta-mercapto-beta,beta-cyclopentamethylenepropionic acid)-O-methyl-tyr(2)-thr(4)-orn(8)-tyr(9)-NH2
• b-Mercapto-b,b-cyclopentaMethylene-propionyl-Tyr(Me)-Ile-Thr-Asn-Cys-Pro-Orn-Tyr-NH2
• (2S)-N-[(2R)-1-[(2S)-2-[[(2S)-5-amino-1-[[(2S)-1-amino-3-(4-methoxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-sulfanylidenepropan-2-yl]-2-[[(2S,3R)-3-hydroxy-2-[[(2S,3S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[2-(1-sulfanylcyclohexyl)acetyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]butanoyl]amino]butanediamide
• (2S)-N-[(2R)-1-[(2S)-2-[[(2S)-5-amino-1-[[(2S)-1-amino-3-(4-methoxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-sulfanylidenepropan-2-yl]-2-[[(2S,3R)-3-hydroxy-2-[[(2S,3S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[2-(1-sulfan

(d(CH₂)₅¹,Tyr(Me)²,Thr⁴,Orn⁸,Tyr-NH₂⁹)-Vasotocin

CAS: 114056-26-7

The oxytocin antagonist OVTA shows enhanced affinity for rat uterine oxytocin receptors after iodination.

Formula: C₅₄H₇₉N₁₁O₁₃S₂

Purezza: 98.7%

Colore e forma: White Powder

Peso molecolare: 1154.42

Ref: 01-4015938

Ota-vasotocin

CAS: 114056-26-7

Ota-vasotocin is a ligand utilized in quantitative receptor autoradiography for oxytocin receptors.

Formula: C₅₄H₇₉N₁₁O₁₃S₂

Peso molecolare: 1154.41

Ref: TM-T25902

(d(CH2)51,Tyr(Me)2,Thr4, Orn 8,Tyr-NH29)-Vasotocin trifluoroacetate salt

CAS: 114056-26-7

Vasotocin is a peptide that belongs to the family of arginine vasotocin and oxytocin receptor antagonists. It is synthesized in the rat kidney, where it is stored in vesicles. Vasotocin has been shown to bind to the oxytocin receptor, which regulates many physiological processes such as muscle contraction, ejaculation, and milk letdown. Vasotocin also modulates the activity of antigen-presenting cells and can be used for pharmaceutical formulations. This drug has been shown to be effective against congestive heart failure and may be used as a diluent for other drugs.br>br>
Vasotocin trifluoroacetate salt (VT) is an oxime derivative that can be isolated from vasotocin. The synthesis of VT involves converting vasotocin into its trifluoroacetate salt by adding trifluoroacetic acid, followed by reacting with hydroxylam

Formula: C₅₄H₇₉N₁₁O₁₃S₂

Purezza: Min. 95%

Peso molecolare: 1,154.4 g/mol

Ref: 3D-FT110427