CAS 1142-20-7

Benzyloxi-carbonil-L-alanina

Descrizione:

Benzyloxi-carbonil-L-alanina, comunemente noto come Z-L-alanina, è un derivato dell'aminoacido alanina in cui il gruppo amminico è protetto da un gruppo benzyloxycarbonile (Z). Questo composto è caratterizzato dalla sua apparente cristallina bianca ed è solubile in solventi organici come metanolo e dimetilsolfossido, ma ha una solubilità limitata in acqua. Il gruppo Z funge da gruppo protettivo nella sintesi dei peptidi, consentendo reazioni selettive senza interferire con i gruppi funzionali dell'aminoacido. Il composto ha una formula molecolare che riflette la sua struttura, incorporando sia la spina dorsale dell'alanina che il gruppo benzyloxycarbonile. La sua stabilità in condizioni di laboratorio standard lo rende un intermedio prezioso nella sintesi organica e nella chimica dei peptidi. Inoltre, la Z-L-alanina è spesso utilizzata nella preparazione di vari peptidi e può essere coinvolta nello studio della struttura e della funzione delle proteine grazie al suo ruolo nella modifica delle sequenze di aminoacidi. I dati di sicurezza indicano che, come molte sostanze chimiche, deve essere maneggiata con cura, seguendo i protocolli di sicurezza appropriati.

Formula: C₁₁H₁₃NO₄

InChI: InChI=1S/C11H13NO4/c1-8(10(13)14)12-11(15)16-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,12,15)(H,13,14)/t8-/m0/s1

InChI key: InChIKey=TYRGLVWXHJRKMT-QMMMGPOBSA-N

SMILES: C(OC(N[C@H](C(O)=O)C)=O)C1=CC=CC=C1

Sinonimi:

• (2S)-2-[[(Benzyloxy)carbonyl]amino]propanoic acid
• (S)-2-(Benzyloxycarbonylamino)propanoic acid
• (S)-2-[(Benzyloxycarbonyl)amino]propionic acid
• <span class="text-smallcaps">L</span>-Alanine, N-[(phenylmethoxy)carbonyl]-
• <span class="text-smallcaps">L</span>-Alanine, N-carboxy-, N-benzyl ester
• <span class="text-smallcaps">L</span>-Carbobenzoxyalanine
• <span class="text-smallcaps">L</span>-Carbobenzyloxyalanine
• <span class="text-smallcaps">L</span>-Cbz alanine
• <span class="text-smallcaps">L</span>-N-(Benzyloxycarbonyl)alanine
• Alanine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• Alanine, N-carboxy-, N-benzyl ester, L-
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-alanine
• Benzyloxycarbonyl-L-alanine
• Cbz-<span class="text-smallcaps">L</span>-Ala-OH
• L-Alanine, N-carboxy-, N-benzyl ester
• L-Carbobenzoxyalanine
• L-Carbobenzyloxyalanine
• L-N-(Benzyloxycarbonyl)alanine
• N-(Benzyloxycarbonyl)-(S)-alanine
• N-(Carbobenzoxy)-<span class="text-smallcaps">L</span>-alanine
• N-(Carbobenzoxy)-L-alanine
• N-Benzoxycarbonyl-<span class="text-smallcaps">L</span>-alanine
• N-Benzoxycarbonyl-L-alanine
• N-Benzyloxycarbonyl-L-alanin
• N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-alanine
• N-Carbobenzyloxy-L-alanine
• N-Cbz alanine
• N-[(Benzyloxy)carbonyl]-<span class="text-smallcaps">L</span>-alanine
• N-[(Benzyloxy)carbonyl]-L-alanine
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-alanine
• N-[(Phenylmethoxy)carbonyl]-L-alanine
• N-benciloxicarbonil-L-alanina
• N-benzyloxycarbonyl-L-alanine
• Nsc 156978
• Nsc 88469
• z-Ala
• N-CBZ-L-Alanine
• (2S)-2-{[(benzyloxy)carbonyl]amino}propanoate
• Cbz-Ala-OH
• Z-L-Alanine
• Z-Ala-OH
• N-Cbz-L-Ala-OH
• N-[(benzyloxy)carbonyl]-D-alanine
• Cbz-L-alanine
• BenzyloxycarbonylLalanine

N-Carbobenzoxy-L-alanine

CAS: 1142-20-7

Formula: C₁₁H₁₃NO₄

Purezza: >99.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 223.23

Ref: 3B-C0633

N-Benzyloxycarbonyl-L-alanine, 98%

CAS: 1142-20-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₁H₁₃NO₄

Purezza: 98%

Colore e forma: crystalline powder, White

Peso molecolare: 223.23

Ref: 02-A16716

Z-Ala-OH

CAS: 1142-20-7

Bachem ID: 4000246.

Formula: C₁₁H₁₃NO₄

Purezza: 99.4%

Colore e forma: White Powder

Peso molecolare: 223.23

Ref: 01-4000246

Z-Ala-OH

CAS: 1142-20-7

Formula: C₁₁H₁₃NO₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 223.2252

Ref: IN-DA003SVU

Z-L-Alanine

CAS: 1142-20-7

Formula: C₁₁H₁₃NO₄

Peso molecolare: 223.23

Ref: 7W-GM6987

Metaraminol Impurity 11

CAS: 1142-20-7

Formula: C₁₁H₁₃NO₄

Peso molecolare: 223.23

Ref: 4Z-M-216014

L-Alanine, N-CBZ protected

CAS: 1142-20-7

L-Alanine, N-CBZ protected

Formula: C₁₁H₁₃NO₄

Purezza: 97%

Colore e forma: white solid

Peso molecolare: 223.22522g/mol

Ref: 54-OR61272

Z-Ala-OH

CAS: 1142-20-7

M03069 - Z-Ala-OH

Formula: C₁₁H₁₃NO₄

Purezza: 97%

Colore e forma: Solid, White powder

Peso molecolare: 223.228

Ref: 10-M03069

N-Benzyloxycarbonyl-L-alanine

Prodotto controllato

CAS: 1142-20-7

Applications N-Benzyloxycarbonyl-L-alanine is an intermediate in the synthesis of Perindopril (P287500), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.
References Lees, K.R., et al.: Brit. J. Clin. Pharmacol., 23, 159 (1987); Morgan, T., et al.: J. Cardiovasc. Pharmacol., 10, Supp. 7, S116, (1987)

Formula: C₁₁H₁₃NO₄

Colore e forma: Neat

Peso molecolare: 223.23

Ref: TR-B286615

Z-L-Alanine extrapure, 99%

CAS: 1142-20-7

Formula: C₁₁H₁₃NO₄

Purezza: min. 99%

Colore e forma: White, Crystalline powder, Clear, Colourless

Peso molecolare: 223.21

Ref: SR-46096

Metaraminol Impurity 11

CAS: 1142-20-7

Formula: C₁₁H₁₃NO₄

Peso molecolare: 223.23

Ref: ST-EA-CP-M97017

Z-L-Alanine

CAS: 1142-20-7

Z-L-Alanine is a cytosolic enzyme inhibitor that inhibits the activity of enzymes involved in protein catalysis. This inhibition is stereoselective, with the L-enantiomer having the stronger inhibitory effect. Z-L-Alanine has been shown to be an effective inhibitor of proteolytic enzymes and has been used as an additive in buffers to prevent enzymatic degradation. Molecular modeling studies have demonstrated that Z-L-Alanine can bind to the active site of these enzymes and inhibit their activity by binding to the catalytic triad of serine, aspartate, and histidine residues. The molecular structure of Z-L-Alanine resembles that of a natural substrate for these enzymes, which may account for its effectiveness in inhibiting them. FTIR spectroscopy has confirmed the presence of Z-L-alanine in a sample obtained from a bacterial culture. Liquid chromatography has shown that this amino acid is present at high levels in various

Formula: C₁₁H₁₃NO₄

Purezza: Min. 95%

Colore e forma: White Off-White Powder

Peso molecolare: 223.23 g/mol

Ref: 3D-FA28886