CAS 1145-80-8

N-(Benzyloxi-carbonile)-L-serina

Descrizione:

N-(Benzyloxi-carbonile)-L-serina, noto anche come Z-L-serina, è un derivato dell'aminoacido L-serina, caratterizzato dalla presenza di un gruppo protettivo benzyloxycarbonile (Z) sul gruppo amminico. Questo composto è tipicamente un solido cristallino bianco o bianco sporco ed è solubile in solventi organici polari come il metanolo e il dimetilsolfossido, ma meno solubile in solventi non polari. È comunemente usato nella sintesi di peptidi come gruppo protettivo per il gruppo amminico, consentendo reazioni selettive nel gruppo carbossilico o nelle catene laterali. Il gruppo Z può essere rimosso in condizioni acide leggere, facilitando la deprotezione del gruppo amminico quando necessario. N-(Benzyloxi-carbonile)-L-serina è anche di interesse nella ricerca biochimica e nelle applicazioni farmaceutiche grazie al suo ruolo nella sintesi di peptidi e proteine. La sua struttura molecolare include un centro chirale, rendendolo otticamente attivo, ed espone proprietà tipiche degli aminoacidi, come la capacità di partecipare a legami idrogeno e formare specie zwitterioniche in soluzione.

Formula: C₁₁H₁₃NO₅

InChI: InChI=1S/C11H13NO5/c13-6-9(10(14)15)12-11(16)17-7-8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,12,16)(H,14,15)/t9-/m0/s1

InChI key: InChIKey=GNIDSOFZAKMQAO-VIFPVBQESA-N

SMILES: C(OC(N[C@H](C(O)=O)CO)=O)C1=CC=CC=C1

Sinonimi:

• (2S)-2-[(Benzyloxycarbonyl)amino]-3-hydroxypropanoic acid
• (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-hydroxypropanoic acid
• (2S)-3-Hydroxy-2-(phenylmethoxycarbonylamino)propanoic acid
• (S)-2-(Benzyloxycarbonylamino)-3-hydroxypropanoic acid
• <span class="text-smallcaps">L</span>-Carbobenzyloxy serine
• <span class="text-smallcaps">L</span>-Serine, N-[(phenylmethoxy)carbonyl]-
• <span class="text-smallcaps">L</span>-Serine, N-carboxy-, N-benzyl ester
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-serine
• Cbz-L-serine
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-serine
• N-Benzyloxycarbonyl-L-serine
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-serine
• N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-serine
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-serine
• N-[(Phenylmethoxy)carbonyl]serine
• N-[(benzyloxy)carbonyl]-L-serine
• N-[(benzyloxy)carbonyl]serine
• N-cbz-l-serine
• NSC 286604
• Serine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• Z-Ser-OH
• L-Serine, N-[(phenylmethoxy)carbonyl]-
• L-Serine, N-carboxy-, N-benzyl ester
• N-[(Phenylmethoxy)carbonyl]-L-serine

N-Benzyloxycarbonyl-L-serine

CAS: 1145-80-8

Formula: C₁₁H₁₃NO₅

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 239.23

Ref: 3B-C0635

N-Benzyloxycarbonyl-L-serine, 99%

CAS: 1145-80-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₁H₁₃NO₅

Purezza: 99%

Colore e forma: Powder, White

Peso molecolare: 239.23

Ref: 02-A19050

Z-Ser-OH

CAS: 1145-80-8

Educt in Hoveyda’s synthesis of L-3-fluoroalanine and N-methyl-L-3-fluoroalanine derivatives via the oxazolidinone.

Formula: C₁₁H₁₃NO₅

Purezza: > 99%

Colore e forma: White

Peso molecolare: 239.23

Ref: 01-4001465

L-Serine, N-[(phenylmethoxy)carbonyl]-

CAS: 1145-80-8

Formula: C₁₁H₁₃NO₅

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 239.2246

Ref: IN-DA000EKT

Z-Ser-OH

CAS: 1145-80-8

Formula: C₁₁H₁₃NO₅

Peso molecolare: 239.23

Ref: 7W-GM2492

Carbobenzyloxy-l-serine

CAS: 1145-80-8

Carbobenzyloxy-l-serine

Purezza: 98%

Peso molecolare: 239.22g/mol

Ref: 54-OR322046

Z-L-Serine extrapure, 99%

CAS: 1145-80-8

Formula: C₁₁H₁₃NO₅

Purezza: min. 99%

Colore e forma: White to Cream powder, Crystalline powder

Peso molecolare: 239.2

Ref: SR-75675

Z-Ser-OH

CAS: 1145-80-8

M03053 - Z-Ser-OH

Formula: C₁₁H₁₃NO₅

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 239.227

Ref: 10-M03053

N-Carboxybenzyl-L-serine-13C3

Prodotto controllato

CAS: 1145-80-8

Applications is an intermediate used in the synthesis of L-3-Phosphoglyceric Acid 13C3 (P358007), which is carbon-13 labelled L-3-Phosphoglyceric Acid. 3-Phosphoglyceric acid is involved in glutamate biosynthesis in syntrophus aciditrophicus. 3-Phosphoglyceric acid can also be used to study pyruvate carboxylation in SDH-deficient kidney mouse cells.
References Kim, M., et al.: Appl. Environ. Microbiol. 81, 8434 (2015); Cardaci, S., et al.: Nat. Cell. Biol. 17, 1317 (2015)

Formula: C₃C₈H₁₃NO₅

Colore e forma: Neat

Peso molecolare: 242.20258

Ref: TR-C182416

N-Carboxybenzyl-L-serine

Prodotto controllato

CAS: 1145-80-8

Applications Building block in peptide synthesis.
References Pansare, S. V.; Org. Synth. 70, 10(1992)

Formula: C₁₁H₁₃NO₅

Colore e forma: Neat

Peso molecolare: 239.22

Ref: TR-C182415

N-Cbz-L-serine

CAS: 1145-80-8

N-Cbz-L-serine is a synthetic amino acid that has been shown to have antimicrobial effects. It has been found to inhibit the growth of bacteria, fungi, and protozoa by inhibiting their cell membranes. This amino acid also inhibits the synthesis of phospholipids in bacterial cell walls and may be used as an antimicrobial agent for industrial applications. N-Cbz-L-serine contains both a hydroxy group and a hydroxyl group, which are essential for its antibacterial activity. The fatty acids present in this compound can be either saturated or unsaturated. Multigram quantities of N-Cbz-L-serine have been produced with high purity using asymmetric synthesis methods.

Formula: C₁₁H₁₃NO₅

Purezza: Min. 95%

Colore e forma: White/Off-White Solid

Peso molecolare: 239.22 g/mol

Ref: 3D-FC19786