CAS 114748-71-9

N-[3-[4-Amino-7-[(2R,5S)-tetraidro-5-(idrossimetil)-2-furanil]-7H-pirrolo[2,3-d]pirimidin-5-il]-2-propin-1-il]-2,2,2-trifluoroacetamide

Descrizione:

N-[3-[4-Amino-7-[(2R,5S)-tetraidro-5-(idrossimetil)-2-furanil]-7H-pirrolo[2,3-d]pirimidin-5-il]-2-propin-1-il]-2,2,2-trifluoroacetamide, con numero CAS 114748-71-9, è un composto organico complesso caratterizzato dalle sue uniche caratteristiche strutturali, inclusi un nucleo di pirrolo[2,3-d]pirimidina e un gruppo funzionale trifluoroacetamide. Questo composto presenta proprietà tipiche dei composti eterociclici, come la potenziale attività biologica dovuta alla presenza di gruppi amino e idrossimetilici, che possono migliorare la sua solubilità e reattività. Il gruppo trifluoroacetamide contribuisce alla sua stabilità e può influenzare la sua interazione con obiettivi biologici. La stereochimica indicata dalla configurazione (2R,5S) suggerisce disposizioni spaziali specifiche che possono influenzare le proprietà farmacologiche del composto. In generale, questa sostanza potrebbe essere di interesse nella chimica medicinale, in particolare nello sviluppo di farmaci mirati a specifiche vie biologiche. Ulteriori studi sarebbero necessari per chiarire il suo completo insieme di caratteristiche, inclusi solubilità, stabilità e attività biologica.

Formula: C₁₆H₁₆F₃N₅O₃

InChI: InChI=1S/C16H16F3N5O3/c17-16(18,19)15(26)21-5-1-2-9-6-24(11-4-3-10(7-25)27-11)14-12(9)13(20)22-8-23-14/h6,8,10-11,25H,3-5,7H2,(H,21,26)(H2,20,22,23)/t10-,11+/m0/s1

InChI key: InChIKey=WUXCPWCITSUNMX-WDEREUQCSA-N

SMILES: C(#CCNC(C(F)(F)F)=O)C=1C=2C(N(C1)[C@@H]3O[C@H](CO)CC3)=NC=NC2N

Sinonimi:

• Acetamide, N-[3-[4-amino-7-[tetrahydro-5-(hydroxymethyl)-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-propynyl]-2,2,2-trifluoro-, (2R-cis)-
• 7H-Pyrrolo[2,3-d]pyrimidine, acetamide deriv.
• Acetamide, N-[3-[4-amino-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-propyn-1-yl]-2,2,2-trifluoro-
• N-[3-[4-Amino-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-propyn-1-yl]-2,2,2-trifluoroacetamide

N-[3-[4-Amino-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-propyn-1-yl]-2,2,2-trifluoroacetamide

CAS: 114748-71-9

Formula: C₁₆H₁₆F₃N₅O₃

Peso molecolare: 383.3251

Ref: IN-DA000F5L

7-TFA-ap-7-Deaza-ddA

CAS: 114748-71-9

Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.

Formula: C₁₆H₁₆F₃N₅O₃

Colore e forma: Solid

Peso molecolare: 383.331

Ref: TM-T38534

7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine

CAS: 114748-71-9

7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a diphosphate nucleoside analogue that can be activated by phosphoramidites. It is a novel, synthetic, and high quality nucleotide with antiviral and anticancer properties. This drug has been shown to inhibit the synthesis of DNA and RNA at the transcriptional level. 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a monophosphate nucleoside analogue that can be used in ribonucleotide synthesis for the treatment of cancer.

Formula: C₁₆H₁₆F₃N₅O₃

Peso molecolare: 383.33 g/mol

Ref: 3D-J-700297

7-Deazaadenosine- 2', 3'- dideoxy- 7[3- (trifluoroacetyl) amino] - 1- propyn- yl

CAS: 114748-71-9

7-Deazaadenosine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 7-Deazaadenosine also has antiviral activity, inhibiting viral DNA synthesis by interfering with the enzyme DNA polymerase. 7-Deazaadenosine has been shown to be more potent than other deoxyribonucleosides against various HIV strains, including HIV-1 group M and HIV-1 group O. This drug was originally developed for use as a chemotherapeutic agent but has since been used as a research reagent for studying the mechanism of action of various drugs on DNA.

Formula: C₁₆H₁₆F₃N₅O₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 383.33 g/mol

Ref: 3D-ND156888