CAS 114753-51-4

CP-47,497

Prodotto controllato

CAS: 114753-51-4

CP-47,497 is a monophenolic synthetic cannabinoid receptor agonist with a strong affinity for the cannabinoid receptor CB1 (Kd= 2.1 nM)1. Binding to the CB1 receptor triggers inhibition of adenylate cyclase as well as inhibition of N-type voltage-dependent Ca2+ channels and activation of MAPK. In vitro assays showed activation of the caspase pathway and resulting dose-dependent cytotoxicity upon CB1 binding to CP-47,497 in neuroblastoma and glioma cell lines2. In vivo studies on experimental mice, rat and canine models showed depression of locomotory activity, anticonvulsant and hypothermic effects, and strong antinociceptive activity3.

Purezza: Min. 95%

Ref: 3D-CC175190

(-)-CP-47947

Prodotto controllato

CAS: 114753-51-4

Formula: C₂₁H₃₄O₂

Colore e forma: Neat

Peso molecolare: 318.49

Ref: TR-C781325

Phenol, 5-(1,1-dimethylheptyl)-2-[(1S,3R)-3-hydroxycyclohexyl]-

CAS: 114753-51-4

Formula: C₂₁H₃₄O₂

Peso molecolare: 318.4935

Ref: IN-DA000F58