CAS 1148-11-4

Benzyloxi-carbonil-L-prolina

Descrizione:

Benzyloxi-carbonil-L-prolina, comunemente noto come Z-Prolina, è un derivato dell'aminoacido prolina, caratterizzato dalla presenza di un gruppo protettivo benzyloxycarbonile (Z). Questo composto è tipicamente utilizzato nella sintesi di peptidi come gruppo protettivo per la funzionalità amminica della prolina, che aiuta a prevenire reazioni indesiderate durante il processo di sintesi. La Z-Prolina è un solido cristallino bianco a bianco sporco che è solubile in solventi organici come metanolo e dimetilsolfossido, ma ha una solubilità limitata in acqua. La sua struttura molecolare include uno scheletro di prolina, che contribuisce alle sue uniche proprietà conformazionali, rendendola preziosa nella progettazione di peptidi e proteine. Il composto è stabile in condizioni normali di laboratorio, ma può subire idrolisi o deprotezione in condizioni acide o basiche. A causa del suo ruolo nella chimica dei peptidi, la Z-Prolina è significativa nella ricerca farmaceutica e nello sviluppo di composti biologicamente attivi. I dati di sicurezza devono essere consultati per la manipolazione, come con qualsiasi sostanza chimica.

Formula: C₁₃H₁₅NO₄

InChI: InChI=1S/C13H15NO4/c15-12(16)11-7-4-8-14(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,16)/t11-/m0/s1

InChI key: InChIKey=JXGVXCZADZNAMJ-NSHDSACASA-N

SMILES: C(OCC1=CC=CC=C1)(=O)N2[C@H](C(O)=O)CCC2

Sinonimi:

• (2S)-1,2-Pyrrolidinedicarboxylic acid 1-(phenylmethyl) ester
• (2S)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid
• (2S)-1-Phenylmethoxycarbonylpyrrolidine-2-carboxylic acid
• (2S)-1-[(benzyloxy)carbonyl]pyrrolidine-2-carboxylate
• (S)-1-(Benzyloxycarbonyl)pyrrolidine-2-carboxylic acid
• 1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester, (2S)-
• 1,2-Pyrrolidinedicarboxylic acid, 1-(phenylmethyl) ester, (S)-
• 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl ester, <span class="text-smallcaps">L</span>-
• 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl ester, L-
• 1-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline
• 1-(Benzyloxycarbonyl)-L-proline
• 1-Carbobenzoxy-<span class="text-smallcaps">L</span>-proline
• 1-Carbobenzoxy-L-proline
• 1-[(Benzyloxy)Carbonyl]Proline
• 1-[(benzyloxy)carbonyl]-D-proline
• 1-[(benzyloxy)carbonyl]-L-proline
• <span class="text-smallcaps">L</span>-Cbz-Proline
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-proline
• Benzyloxycarbonyl-L-proline
• Carbobenzoxy-<span class="text-smallcaps">L</span>-proline
• Carbobenzoxy-L-proline
• Carbobenzoxy-S-proline
• Carbobenzyloxy-<span class="text-smallcaps">L</span>-proline
• Carbobenzyloxy-L-proline
• Cbz-<span class="text-smallcaps">L</span>-Pro-OH
• Cbz-L-Pro-OH
• Cbz-L-proline
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline
• N-(Carbobenzyloxy)-<span class="text-smallcaps">L</span>-proline
• N-Benzyloxycarbonyl-(S)-proline
• N-Benzyloxycarbonyl-L-prolin
• N-Benzyloxycarbonyl-L-proline
• N-CBZ-L-Proline N-Carbobenzyloxy-L-proline
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-proline
• N-Carbobenzoxy-L-proline
• N-Carbobenzyloxy-(S)-proline
• N-Cbz-<span class="text-smallcaps">L</span>-proline
• N-Cbz-L-Pro-OH
• N-Cbz-L-proline
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-proline
• N-[(Phenylmethoxy)carbonyl]-L-proline
• N-benciloxicarbonil-L-prolina
• N-cbz-L-proline crystalline
• Z-L-Proline
• Z-Pro-OH
• N-CARBOBENZYLOXY-L-PROLINE
• N-ALPHA-BENZYLOXYCARBONYL-L-PROLINE
• N-ALPHA-CBZ-L-PROLINE
• (2S)-1-[(BENZYLOXY)CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID
• CBZ-PRO-OH
• N-ALPHA-CARBOBENZOXY-L-PROLINE
• (S)-N-CBZ-PYRROLIDINE-2-CARBOXYLIC ACID
• N-CBZ-L-PROLINE-OH
• Z-L-PRO-OH
• N-ALPHA-CARBOBENZOXY-L-PYRROLIDINE-2-CARBOXYLIC ACID
• L-CBZ-PROLINE

N-Benzyloxycarbonyl-L-proline

CAS: 1148-11-4

Formula: C₁₃H₁₅NO₄

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 249.27

Ref: 3B-C0713

N-Benzyloxycarbonyl-L-proline, 98+%

CAS: 1148-11-4

N-(Benzyloxycarbonyl)-L-proline is a potent inhibitor of prolidase; a specific peptidase that cleaves dipeptides with a C-terminal prolyl and hydroxylprolyl residue. It is also used in the synthesis of N-(L-Prolyl)--alanine which is a derivative of the naturally occurring beta amino acid -Alanine. T

Formula: C₁₃H₁₄NO₄

Purezza: 98+%

Colore e forma: Powder or crystalline powder or crystals or granules, White to cream

Peso molecolare: 248.26

Ref: 02-B21672

Z-Pro-OH

CAS: 1148-11-4

Bachem ID: 4001343.

Formula: C₁₃H₁₅NO₄

Purezza: 99.1%

Colore e forma: White

Peso molecolare: 249.27

Ref: 01-4001343

Z-Pro-OH

CAS: 1148-11-4

Formula: C₁₃H₁₅NO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 249.2625

Ref: IN-DA007RF9

(2S)-Pyrrolidine-2-carboxylic acid, N-CBZ protected

CAS: 1148-11-4

(2S)-Pyrrolidine-2-carboxylic acid, N-CBZ protected

Formula: C₁₃H₁₅NO₄

Purezza: 98%

Colore e forma: white solid

Peso molecolare: 249.26g/mol

Ref: 54-OR61280

Carbobenzoxyproline

CAS: 1148-11-4

Carbobenzoxyproline

Purezza: ≥98%

Peso molecolare: 249.26g/mol

Ref: 54-BUP19312

Z-Pro-OH

CAS: 1148-11-4

Formula: C₁₃H₁₅NO₄

Peso molecolare: 249.27

Ref: 7W-GM1976

Carbobenzoxyproline

CAS: 1148-11-4

Carbobenzoxyproline (Carbobenzoxy-S-proline) is a prolidase inhibitor.

Formula: C₁₃H₁₅NO₄

Purezza: 99.79%

Colore e forma: White To Light Yellow Crystal Powder

Peso molecolare: 249.26

Ref: TM-T20125

Z-Pro-OH

CAS: 1148-11-4

M03066 - Z-Pro-OH

Formula: C₁₃H₁₅NO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 249.266

Ref: 10-M03066

N-Benzyloxycarbonyl-L-proline

CAS: 1148-11-4

N-Benzyloxycarbonyl-L-proline is a cationic polymerization inhibitor that has been shown to inhibit the growth of Pseudomonas aeruginosa. It inhibits bacterial growth by inhibiting the production of collagen, an important component in the cell wall. N-Benzyloxycarbonyl-L-proline is also used as a histological staining agent and has been shown to be effective against breast cancer cells resistant to tamoxifen therapy.

Formula: C₁₃H₁₅NO₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 249.26 g/mol

Ref: 3D-FB37965

Z-L-Proline extrapure, 99%

CAS: 1148-11-4

Formula: C₁₃H₁₅NO₄

Purezza: min. 99%

Colore e forma: White, Crystalline powder

Peso molecolare: 249.3

Ref: SR-31688

N-(Benzyloxycarbonyl)-L-proline

Prodotto controllato

CAS: 1148-11-4

Applications N-(Benzyloxycarbonyl)-L-proline is a potent in vitro and in vivo inhibitor of prolidase; a specific peptidase that cleaves dipeptides with a C-terminal prolyl and hydroxylprolyl residue. N-(Benzyloxycarbonyl)-L-proline is also used in the synthesis of N-(L-Prolyl)-β-alanine (P756190) which is a derivative of the naturally occurring beta amino acid β-Alanine (A637320).
References Lupi, A., et al.: BBA-Mol. Cell Res., 1744, 157 (2005)

Formula: C₁₃H₁₅NO₄

Colore e forma: Neat

Peso molecolare: 249.26

Ref: TR-B287810

Acalabrutinib Impurity 18

CAS: 1148-11-4

Formula: C₁₃H₁₅NO₄

Peso molecolare: 249.27

Ref: ST-EA-CP-A165007