CAS 1152-61-0

Acido benzyloxycarbonil-L-aspartico

Descrizione:

Acido benzyloxycarbonil-L-aspartico, comunemente noto come Z-Asp, è un derivato dell'aminoacido acido aspartico, caratterizzato dalla presenza di un gruppo protettivo benzyloxycarbonile (Z). Questo composto è tipicamente utilizzato nella sintesi di peptidi come gruppo protettivo per la funzionalità amminica dell'acido aspartico, il che aiuta a prevenire reazioni indesiderate durante il processo di sintesi. Il gruppo Z è stabile in condizioni basiche, ma può essere rimosso in condizioni acide, consentendo una deprotezione selettiva. Acido benzyloxycarbonil-L-aspartico è un solido cristallino bianco a bianco sporco ed è solubile in solventi organici come metanolo e dimetilsolfossido (DMSO), ma ha una solubilità limitata in acqua. La sua struttura molecolare include un gruppo funzionale acido carbossilico, contribuendo alle sue proprietà acide. Il composto è utilizzato in varie applicazioni biochimiche, inclusa la sintesi di peptidi e proteine, e funge da intermediario importante nello sviluppo di farmaci. La corretta manipolazione e conservazione sono essenziali a causa della sua reattività e del potenziale di idrolisi in ambienti acquosi.

Formula: C₁₂H₁₃NO₆

InChI: InChI=1S/C12H13NO6/c14-10(15)6-9(11(16)17)13-12(18)19-7-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,18)(H,14,15)(H,16,17)/t9-/m0/s1

InChI key: InChIKey=XYXYXSKSTZAEJW-VIFPVBQESA-N

SMILES: C(OC(N[C@@H](CC(O)=O)C(O)=O)=O)C1=CC=CC=C1

Sinonimi:

• (2S)-2-(Phenylmethoxycarbonylamino)butanedioic acid
• (2S)-2-[[(Benzyloxy)carbonyl]amino]butanedioic acid
• (2S)-2-{[(benzyloxy)carbonyl]amino}butanedioate
• <span class="text-smallcaps">L</span>-Aspartic acid, N-[(phenylmethoxy)carbonyl]-
• Aspartic acid, N-carboxy-, N-benzyl ester
• Aspartic acid, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid
• CBZ-L-Aspartic Acid-OH
• Carbobenzoxy-<span class="text-smallcaps">L</span>-aspartic acid
• Cbz-Asp-OH
• Cbz-L-aspartic acid
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-aspartic acid
• N-Benzyloxycarbonyl-L-aspartic acid
• N-Benzyloxylcarbonyl-<span class="text-smallcaps">L</span>-aspartic acid
• N-CBZ-L-Aspartic acid N-Carbobenzyloxy-L-aspartic acid
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-aspartic acid
• N-Carbobenzoxy-L-aspatic acid
• N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-aspartic acid
• N-Cbz-L-Asp-OH
• N-Cbz-L-aspartic acid
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-aspartic acid
• N-[(benzyloxy)carbonyl]-D-aspartic acid
• N-[(benzyloxy)carbonyl]-L-aspartic acid
• N-[(benzyloxy)carbonyl]aspartic acid
• N-cbz-L-aspartic acid crystalline
• NALPHA-Benzyloxycarbonyl-L-aspartic acid
• NSC 88479
• NSC 9972
• Z-Asp-OH
• Z-L-Aspartic acid
• z-Asp
• Carbobenzoxy-L-aspartic acid
• N-[(Phenylmethoxy)carbonyl]-L-aspartic acid
• Aspartic acid, N-carboxy-, N-benzyl ester, L-

N-Benzyloxycarbonyl-L-aspartic Acid

CAS: 1152-61-0

Formula: C₁₂H₁₃NO₆

Purezza: >99.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 267.24

Ref: 3B-C0629

Z-Asp-OH

CAS: 1152-61-0

Bachem ID: 4000471.

Formula: C₁₂H₁₃NO₆

Purezza: > 98%

Colore e forma: White

Peso molecolare: 267.24

Ref: 01-4000471

L-Aspartic acid, N-[(phenylmethoxy)carbonyl]-

CAS: 1152-61-0

Formula: C₁₂H₁₃NO₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 267.2347

Ref: IN-DA000GEV

N-Cbz-L-Aspartic Acid

CAS: 1152-61-0

N-Cbz-L-Aspartic Acid

Purezza: 99%

Peso molecolare: 267.23g/mol

Ref: 54-OR1014324

N-Z-L-aspartic acid

CAS: 1152-61-0

Formula: C₁₂H₁₃NO₆

Purezza: ≥ 98.0%

Colore e forma: White to off-white solid

Peso molecolare: 267.24

Ref: 7W-GM2849

N-Cbz-L-aspartic Acid

Prodotto controllato

CAS: 1152-61-0

Applications N-Cbz-L-aspartic acid is an N-Cbz-protected form of L-Aspartic acid (A790024). L-Aspartic acid is a nonessential amino acid that is used to biosynthesize other amino acids within the human body. L-Aspartic acid also increases membrane conductance of mammalian neurons by voltage-dependent means, causing depolarization and nerve impulses that travel to key areas of the central nervous system.
References Anderson, H., et al.: J. Nutr., 99, 82 (1969); Honey, C., et al.: Neurosci. Lett., 61, 135 (1985); MacDonald, J., et al.: Brain Res., 237, 248 (1982)

Formula: C₁₂H₁₃NO₆

Colore e forma: White To Off-White

Peso molecolare: 267.23

Ref: TR-C176285

Z-L-Aspartic Acid extrapure, 99%

CAS: 1152-61-0

Formula: C₁₂H₁₃NO₆

Purezza: min. 99%

Colore e forma: White to off white, Crystalline powder

Peso molecolare: 267.2

Ref: SR-63143

Z-Asp-OH

CAS: 1152-61-0

M03043 - Z-Asp-OH

Formula: C₁₂H₁₃NO₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 267.237

Ref: 10-M03043

Z-L-Asp-OH

CAS: 1152-61-0

Z-L-Asp-OH is a protease inhibitor that inhibits the activity of serine proteases, including trypsin and chymotrypsin. Z-L-Asp-OH binds to the active site of these enzymes and prevents them from cleaving their substrates. The optimal pH for this enzyme is 8.0, which corresponds to its maximum level of activity. Z-L-Asp-OH also has apoptotic activities in cells by causing cellular pathway changes, leading to cell death via programmed cell death or apoptosis. This agent is activated by hydrolysis at ester linkages and polymerizes into films in aqueous solution at physiological pH. It has been shown to inhibit the growth of human ovarian carcinoma cells in vitro, but not normal cells.

Formula: C₁₂H₁₃NO₆

Purezza: Min. 95%

Peso molecolare: 267.23 g/mol

Ref: 3D-FA36771

N-Benzyloxycarbonyl-L-aspartic Acid

CAS: 1152-61-0

Formula: C₁₂H₁₃NO₆

Peso molecolare: 267.24

Ref: ST-EA-CP-A126021