CAS 115479-40-8

4-Cloro-7-[5-O-[(1,1-dimetiletil)dimetilsilil]-2,3-O-(1-metiletilidene)-β-D-ribofuranosil]-7H-pirrolo[2,3-d]pirimidin-2-ammina

Descrizione:

4-Cloro-7-[5-O-[(1,1-dimetiletil)dimetilsilil]-2,3-O-(1-metiletilidene)-β-D-ribofuranosil]-7H-pirrolo[2,3-d]pirimidin-2-ammina, con numero CAS 115479-40-8, è un composto organico complesso caratterizzato dalle sue uniche caratteristiche strutturali, inclusi un nucleo di pirrolo[2,3-d]pirimidina e vari gruppi funzionali. La presenza di un sostituente cloro e di un gruppo etere sililico indica una potenziale reattività e stabilità in determinate condizioni. Il gruppo β-D-ribofuranosilico suggerisce che questo composto possa mostrare attività biologica, interagendo possibilmente con acidi nucleici o enzimi. La sua struttura intricata, che include i gruppi dimetilsilile e isopropilidene, può influenzare la sua solubilità, polarità e proprietà farmacocinetiche complessive. Tali composti sono spesso di interesse nella chimica medicinale per le loro potenziali applicazioni terapeutiche, in particolare nella ricerca antivirale o anticancro. Tuttavia, proprietà specifiche come il punto di fusione, il punto di ebollizione e la solubilità richiederebbero dati empirici per una caratterizzazione precisa.

Formula: C₂₀H₃₁ClN₄O₄Si

InChI: InChI=1S/C20H31ClN4O4Si/c1-19(2,3)30(6,7)26-10-12-13-14(29-20(4,5)28-13)17(27-12)25-9-8-11-15(21)23-18(22)24-16(11)25/h8-9,12-14,17H,10H2,1-7H3,(H2,22,23,24)/t12-,13-,14-,17-/m1/s1

InChI key: InChIKey=WXKYMEIKPSQDLH-VMUDFCTBSA-N

SMILES: C(O[Si](C(C)(C)C)(C)C)[C@H]1O[C@H]([C@]2([C@@]1(OC(C)(C)O2)[H])[H])N3C=4C(C=C3)=C(Cl)N=C(N)N4

Sinonimi:

• 4-Chloro-7-[5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)--D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine
• 4-Chloro-7-[5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β-<span class="text-smallcaps">D</span>-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine
• 7H-Pyrrolo[2,3-d]pyrimidin-2-amine, 4-chloro-7-[5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β-<span class="text-smallcaps">D</span>-ribofuranosyl]-
• Furo[3,4-d]-1,3-dioxole, 7H-pyrrolo[2,3-d]pyrimidin-2-amine deriv.
• 4-Chloro-7-[5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine
• 7H-Pyrrolo[2,3-d]pyrimidin-2-amine, 4-chloro-7-[5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β-D-ribofuranosyl]-

7H-Pyrrolo[2,3-d]pyrimidin-2-amine, 4-chloro-7-[5-O-[(1,1-dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β-D-ribofuranosyl]-

CAS: 115479-40-8

Formula: C₂₀H₃₁ClN₄O₄Si

Colore e forma: Solid

Peso molecolare: 455.023

Ref: IN-DA000G1Y

9-(5''-O-t-Butyldimethylsilyl-2'',3''-O-isopropylidene-b-D-ribofuranosyl)-6-chloro-7-deazaguanine

CAS: 115479-40-8

Ref: 7W-GN6737

9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene-b-D-ribofuranosyl)-6-chloro-7-deazaguanine

CAS: 115479-40-8

9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene-b-D-ribofuranosyl)-6-chloro-7-deazaguanine is a novel nucleoside phosphoramidite. It is an analogue of the nucleoside 7-(4,4'-dimethoxytrityl)guanine and 9-(4,4'-dimethoxytrityl)guanine. This product has been shown to have anticancer activity and antiviral activity against HIV in vitro. 9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene b -D ribofuranosyl)-6 chloro -7 deazaguanine has also been shown to inhibit DNA synthesis in cells. The purity of this product is over 98%. It is a novel compound that

Formula: C₂₀H₃₃ClN₄O₄Si

Purezza: Min. 95%

Peso molecolare: 457.04 g/mol

Ref: 3D-NB10265