CAS 1164-16-5

Carbobenzossi-L-tirosina

Descrizione:

Carbobenzossi-L-tirosina, noto anche come Z-Tyr-OH, è un derivato dell'aminoacido tirosina, in cui il gruppo amminico è protetto da un gruppo carbobenzossilico (Z). Questo composto è caratterizzato dalla sua apparente cristallina bianca a bianco sporco ed è solubile in solventi organici come metanolo e dimetilsolfossido, ma ha una solubilità limitata in acqua. È comunemente utilizzato nella sintesi di peptidi come gruppo protettore per la funzionalità amminica della tirosina, consentendo reazioni selettive senza interferenze dal gruppo amminico. Il gruppo Z può essere rimosso in condizioni specifiche, facilitando la successiva formazione di peptidi. Carbobenzossi-L-tirosina è utilizzato anche in varie applicazioni biochimiche, inclusi studi sull'attività enzimatica e interazioni proteiche. La sua stabilità e reattività lo rendono un intermedio prezioso nella sintesi organica e nello sviluppo farmaceutico. Come per molte sostanze chimiche, è necessario osservare le opportune precauzioni di manipolazione e sicurezza a causa dei potenziali rischi associati al suo uso.

Formula: C₁₇H₁₇NO₅

InChI: InChI=1S/C17H17NO5/c19-14-8-6-12(7-9-14)10-15(16(20)21)18-17(22)23-11-13-4-2-1-3-5-13/h1-9,15,19H,10-11H2,(H,18,22)(H,20,21)/t15-/m0/s1

InChI key: InChIKey=MCRMUCXATQAAMN-HNNXBMFYSA-N

SMILES: C([C@H](NC(OCC1=CC=CC=C1)=O)C(O)=O)C2=CC=C(O)C=C2

Sinonimi:

• (2S)-2-(Benzyloxycarbonylamino)-3-(4-hydroxyphenyl)propanoic acid
• (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid
• (2S)-2-{[(benzyloxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate
• (2S)-3-(4-Hydroxyphenyl)-2-(phenylmethoxycarbonylamino)propanoic acid
• (Benzyloxycarbonyl)tyrosine
• 2-{[(Benzyloxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoic acid
• <span class="text-smallcaps">L</span>-(Carbobenzyloxy)tyrosine
• <span class="text-smallcaps">L</span>-Tyrosine, N-[(phenylmethoxy)carbonyl]-
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine
• BenzyloxycarbonylLtyrosine
• CBZ-L-Tyrosine-OH
• Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine
• Carbobenzoxytyrosine
• Cbz-L-tyrosine
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-tyrosine
• N-(Benzyloxycarbonyl)tyrosine
• N-Benzyloxycarbonyl-L-tyrosine~Z-Tyr-OH
• N-CBZ-<span class="text-smallcaps">L</span>-tyrosine
• N-CBZ-L-Tyrosine N-Carbobenzyloxy-L-tyrosine
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine
• N-Carbobenzoxytyrosine
• N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-tyrosine
• N-Carbobenzyloxy-L-tyrosine dihydrate
• N-Cbz-L-tyrosine
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tyrosine
• N-[(benzyloxy)carbonyl]tyrosine
• N-cbz-L-tyrosine crystalline
• NSC 88488
• Na-Benzyloxycarbonyl-L-tyrosine
• Tyrosine, N-carboxy-, N-benzyl ester
• Tyrosine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• Z-L-Tyr
• Z-L-tyrosine dihydrate
• Z-L-tyrosine hydrate
• Z-Tyr-OH hydrate
• Z-Tyr-Oh
• Tyrosine, N-carboxy-, N-benzyl ester, L-
• L-Tyrosine, N-[(phenylmethoxy)carbonyl]-
• N-[(Phenylmethoxy)carbonyl]-L-tyrosine

N-Benzyloxycarbonyl-L-tyrosine, 99%, may contain up to ca 10% water

CAS: 1164-16-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₇H₁₇NO₅

Purezza: 99%

Colore e forma: White to pale cream, Powder

Peso molecolare: 315.33

Ref: 02-A10966

Z-Tyr-OH

CAS: 1164-16-5

Bachem ID: 4001149.

Formula: C₁₇H₁₇NO₅

Purezza: 99.68%

Colore e forma: Whitish

Peso molecolare: 315.33

Ref: 01-4001149

L-Tyrosine, N-[(phenylmethoxy)carbonyl]-

CAS: 1164-16-5

Formula: C₁₇H₁₇NO₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 315.3206

Ref: IN-DA000CER

Z-Tyr-OH

CAS: 1164-16-5

Formula: C₁₇H₁₇NO₅

Peso molecolare: 315.33

Ref: 7W-GM1261

L-Tyrosine, N-CBZ protected

CAS: 1164-16-5

L-Tyrosine, N-CBZ protected

Purezza: 98%

Peso molecolare: 315.32g/mol

Ref: 54-OR0222

N-Benzyloxycarbonyl-L-tyrosine

CAS: 1164-16-5

Formula: C₁₇H₁₇NO₅

Purezza: >98.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 315.33

Ref: 3B-C1729

z-tyr-oh

CAS: 1164-16-5

Formula: C₁₇H₁₇NO₅

Purezza: 98%

Colore e forma: Beige powder

Peso molecolare: 315.325

Ref: 10-F045507

N-Cbz-L-tyrosine

CAS: 1164-16-5

N-Cbz-L-tyrosine is a covalently modified amino acid that has been shown to be an effective protease inhibitor. The compound binds to the active site of enzymes, blocking their ability to hydrolyze proteins. In addition, N-Cbz-L-tyrosine has been shown to inhibit aminopeptidases and carboxypeptidases with IC50 values of 0.5 mM and 1 mM, respectively. This protein stabilizer has been shown to have a solubility data of 0.4 g/100 mL in water and 0.3 g/100 mL in methanol. It also has a molecular weight of 184.2 g/mol and a pH optimum of 7.0 (±0.2).

Formula: C₁₇H₁₇NO₅

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 315.32 g/mol

Ref: 3D-FC29911

Z-L-Tyrosine extrapure, 99%

CAS: 1164-16-5

Formula: C₁₇H₁₇NO₅

Purezza: min. 99%

Colore e forma: White To Off white, Crystalline powder

Peso molecolare: 315.3

Ref: SR-31078

N-Cbz-L-tyrosine

Prodotto controllato

CAS: 1164-16-5

Applications N-Cbz-L-tyrosine is an N-Cbz-protected form of L-Tyrosine (T899975). L-Tyrosine is an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines (e.g. Norepinephrine HCl [N674500]) in human keratinocytes, and also for the synthesis of proteins and thyroid hormones.
References Gülçin, ?.: Amino Acids, 32, 431 (2007); Langen, K., et al.: Nuc. Med. Biol., 29, 625 (2002); Schallreuter, K., et al.: J. Invest. Derm., 104, 953 (1995); Zhang, W., et al.: Neuropharmacology, 47, 438 (2004)

Formula: C₁₇H₁₇NO₅

Colore e forma: Neat

Peso molecolare: 315.32

Ref: TR-C227855