CAS 116560-97-5

acido 4-[[(1S)-1-[[(2S)-2-[[(2S)-2-[(1-carbossi-3-fenil-propil)amino]propanol]amino]propanol]carbamoil]-2-fenil-etil]amino]benzoico

Descrizione:

La sostanza chimica nota come acido 4-[[(1S)-1-[[(2S)-2-[[(2S)-2-[(1-carbossi-3-fenil-propil)amino]propanol]amino]propanol]carbamoil]-2-fenil-etil]amino]benzoico, con il numero CAS 116560-97-5, è un composto organico complesso caratterizzato dalla sua struttura multifunzionale, che include più residui di amminoacidi e un gruppo acido carbossilico. Questo composto è probabile che mostri proprietà tipiche dei peptidi o di molecole simili ai peptidi, come la solubilità in solventi polari e una potenziale attività biologica, possibilmente come agente farmaceutico o sonda biochimica. La sua struttura suggerisce la presenza di centri chirali, che possono conferire specifiche proprietà stereochimiche che influenzano la sua interazione con obiettivi biologici. La presenza di gruppi fenilici indica un potenziale per interazioni aromatiche, mentre il moiety acido carbossilico può contribuire alla sua acidità e capacità di formare sali. In generale, la struttura intricata di questo composto suggerisce un ruolo in sistemi biologici complessi, potenzialmente coinvolgendo interazioni enzimatiche o legame ai recettori.

Formula: C₃₂H₃₆N₄O₇

InChI: InChI=1/C32H36N4O7/c1-20(33-26(32(42)43)18-13-22-9-5-3-6-10-22)28(37)34-21(2)29(38)36-30(39)27(19-23-11-7-4-8-12-23)35-25-16-14-24(15-17-25)31(40)41/h3-12,14-17,20-21,26-27,33,35H,13,18-19H2,1-2H3,(H,34,37)(H,40,41)(H,42,43)(H,36,38,39)/t20-,21-,26?,27-/m0/s1

SMILES: C[C@@H](C(=N[C@@H](C)C(=NC(=O)[C@H](Cc1ccccc1)Nc1ccc(cc1)C(=O)O)O)O)NC(CCc1ccccc1)C(=O)O

Sinonimi:

• N-(1-carboxy-3-phenylpropyl)-alanyl-alanyl-phenylalanine-4-aminobenzoate
• N-(1-carboxy-3-phenylpropyl)-L-alanyl-N-{(2S)-2-[(4-carboxyphenyl)amino]-3-phenylpropanoyl}-L-alaninamide

N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH

CAS: 116560-97-5

Specific inhibitor of thimet oligopeptidase (soluble metalloendopeptidase, EC 3.4.24.15) (Ki = 0.027 ± 0.003 µM). Neprilysin (Endopeptidase-2, EC 3.4.24.11) converts Cpp-AAF-pAb into a potent inhibitor of angiotensin-converting enzyme (ACE).

Formula: C₃₂H₃₆N₄O₇

Purezza: 98.2%

Colore e forma: White Powder

Peso molecolare: 588.66

Ref: 01-4050213

Cpp-AAF-pAb

CAS: 116560-97-5

Cpp-AAF-pAb is a synthetic peptide that corresponds to the amino acid sequence of the C terminus of human basic fibroblast growth factor (bFGF) and has been shown to have a variety of effects on cells. It has been used in cell culture studies to measure the effect of bFGF on renal blood flow, which is an important marker for kidney disease. In addition, this peptide inhibits tumor cell growth and has antinociceptive properties in rats. The inhibition of tumor cell growth may be due to its ability to inhibit metalloendopeptidases and polyclonal antibodies.

Formula: C₃₂H₃₆N₄O₇

Purezza: Min. 95%

Peso molecolare: 588.67 g/mol

Ref: 3D-IAP-3754-PI

N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH trifluoroacetate salt

CAS: 116560-97-5

The N-[(RS)-1-carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH trifluoroacetate salt is a synthetic substrate for the study of metalloendopeptidase. This compound was used to develop a model system to study the function of human liver, and has been shown to inhibit the growth of PC12 cells. The N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH trifluoroacetate salt is also an experimental model for congestive heart failure. This compound has been shown to increase glomerular filtration rate in experimental animals as well as basic fibroblast growth factor activity in cell culture by increasing intracellular calcium levels.

Formula: C₃₂H₃₆N₄O₇

Purezza: Min. 95%

Peso molecolare: 588.65 g/mol

Ref: 3D-FR111118