CAS 116896-29-8

(1E)-1-[(3'aS,4'R,5'R,6'aR)-5'-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-5,5-dimethylspiro[1,3-dioxane-2,2'(1'H)-pentalen]-4'-yl]-4-methyl-1-octen-6-yn-3-one

Prodotto controllato

CAS: 116896-29-8

Applications (1E)-1-[(3'aS,4'R,5'R,6'aR)-5'-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-5,5-dimethylspiro[1,3-dioxane-2,2'(1'H)-pentalen]-4'-yl]-4-methyl-1-octen-6-yn-3-one is an intermediate in the synthesis of Iloprost (I267300),a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, raynaud's phenomenon and ischemia.
References Gais, H. J., et al.: Chem. Euro. J., 12, 5610 (2006);

Formula: C₂₈H₄₆O₄Si

Colore e forma: Neat

Peso molecolare: 474.75

Ref: TR-D473525