CAS 1173-13-3

Previtamina D3

Descrizione:

Previtamina D3, noto anche come 7-deidrocolesterolo, è un composto sterolico che gioca un ruolo cruciale nella biosintesi della vitamina D nel corpo umano. Si trova principalmente nella pelle ed è sintetizzato dal colesterolo quando esposto alla radiazione ultravioletta B (UVB) della luce solare. La struttura chimica di Previtamina D3 include uno scheletro steroideo, caratteristico degli steroli, e subisce un processo di isomerizzazione termica per convertirsi in vitamina D3 (colecalciferolo) quando esposto al calore. Previtamina D3 è un solido incolore o giallo pallido a temperatura ambiente ed è insolubile in acqua ma solubile in solventi organici. La sua importanza biologica risiede nella sua conversione in vitamina D3, essenziale per l'omeostasi del calcio e la salute delle ossa. Le carenze di vitamina D possono portare a vari problemi di salute, tra cui rachitismo nei bambini e osteomalacia negli adulti. Il composto è anche di interesse nella ricerca relativa alla salute della pelle e agli effetti della radiazione UV.

Formula: C₂₇H₄₄O

InChI: InChI=1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h10,12-13,19,21,24-26,28H,6-9,11,14-18H2,1-5H3/b13-12-/t21-,24+,25-,26+,27-/m1/s1

InChI key: InChIKey=YUGCAAVRZWBXEQ-WHTXLNIXSA-N

SMILES: C[C@@]12[C@](C(/C=C\C3=C(C)CC[C@H](O)C3)=CCC1)(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]

Sinonimi:

• (1S)-3-[(1Z)-2-[(1R,3aR,7aR)-1-[(1R)-1,5-Dimethylhexyl]-2,3,3a,6,7,7a-hexahydro-7a-methyl-1H-inden-4-yl]ethenyl]-4-methyl-3-cyclohexen-1-ol
• (1S)-3-[2-[(1R,3aR,7aR)-1-[(1R)-1,5-dimethylhexyl]-7a-methyl-1,2,3,3a,6,7-hexahydroinden-4-yl]vinyl]-4-methyl-cyclohex-3-en-1-ol
• (3S,6Z,14β)-9,10-secocholesta-5(10),6,8-trien-3-ol
• (3beta,6Z)-9,10-Secocholesta-5(10),6,8-trien-3-ol
• 3-Cyclohexen-1-ol, 3-[(1Z)-2-[(1R,3aR,7aR)-1-[(1R)-1,5-dimethylhexyl]-2,3,3a,6,7,7a-hexahydro-7a-methyl-1H-inden-4-yl]ethenyl]-4-methyl-, (1S)-
• 9,10-Secocholesta-5(10),6,8-trien-3-ol, (3β,6Z)-
• 9,10-Secocholesta-5(10),6,8-trien-3β-ol
• Precalciferol
• Precalciferol₃
• Precholecalciferol
• Previtamin D
• Previtamin D(3)
• Previtamin D₃

Previtamin D3

CAS: 1173-13-3

Previtamin D3

Purezza: 80%

Peso molecolare: 384.64g/mol

Ref: 54-OR1075432

Precalciferol (Previtamin D3)

CAS: 1173-13-3

Formula: C₂₇H₄₄O

Peso molecolare: 384.65

Ref: 4Z-C-5110

Previtamin D3

CAS: 1173-13-3

Previtamin D3 is an intermediate in the production of cholecalciferol (vitamin D3).

Formula: C₂₇H₄₄O

Colore e forma: Solid

Peso molecolare: 384.648

Ref: TM-T38553

Previtamin D3 (>80%)

Prodotto controllato

CAS: 1173-13-3

Stability Light Sensitive, Temperature Sensitive
Applications Vitamin D3 (V676045) isomer. Vitamin D3 mediates intestinal calcium absorbtion, bone calcium metabolism and many other processes. During exposure to sunlight 7-dehydrocholesterol in converted to pre-vitamin D3, which undergoes a rapid transformation within the plasma membrane to vitamin D3.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Holick, M. et al.; J. Bone. Miner. Metab. 22, V28 (2007); Tian, X. & Holick, M.; J. Biol. Chem. 270, 8706 (1995)

Formula: C₂₇H₄₄O

Purezza: >80%

Colore e forma: Colourless

Peso molecolare: 384.64

Ref: TR-P713510

Precholecalciferol

CAS: 1173-13-3

Precholecalciferol is a vitamin D analog that has been shown to be active in the target tissue. It is used for the treatment of chronic kidney disease and autoimmune diseases, including multiple sclerosis. The activated form of this drug is converted to calcitriol by hydroxylation, which is then metabolized by the liver. This form of the drug can also be converted by epoxide hydrolase to 25-hydroxycholecalciferol, which can be further metabolized by cytochrome P450 enzymes to 1,25-dihydroxycholecalciferol (1,25-(OH)2D3). This form of the drug can bind to nuclear receptors and activate gene transcription. Precholecalciferol has been shown to activate growth factors such as insulin-like growth factor-I and platelet-derived growth factor, which may contribute to its role in treating autoimmune diseases.

Formula: C₂₇H₄₄O

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 384.64 g/mol

Ref: 3D-FP159099