CAS 117976-89-3

Rabeprazolo

Descrizione:

Rabeprazolo è un inibitore della pompa protonica (PPI) comunemente usato per trattare condizioni come la malattia da reflusso gastroesofageo (GERD) e le ulcere peptiche riducendo la produzione di acido gastrico. È caratterizzato dalla sua formula chimica, che include un gruppo sulfinile, e la sua struttura presenta un anello di piridina, contribuendo alla sua attività farmacologica. Rabeprazolo viene tipicamente somministrato nella sua forma di sale sodico ed è noto per il suo rapido inizio d'azione e la durata relativamente lunga dell'effetto. La sostanza è generalmente ben assorbita nel tratto gastrointestinale, con la sua biodisponibilità influenzata dall'assunzione di cibo. Rabeprazolo viene metabolizzato principalmente nel fegato attraverso gli enzimi del citocromo P450, portando a vari metaboliti, alcuni dei quali sono farmacologicamente attivi. I suoi effetti terapeutici sono spesso accompagnati da un profilo di sicurezza favorevole, sebbene gli effetti collaterali potenziali possano includere mal di testa, disturbi gastrointestinali e, in rari casi, condizioni più gravi. In generale, Rabeprazolo è un farmaco efficace per la gestione dei disturbi legati all'acido, contribuendo a migliorare i risultati dei pazienti nella salute gastrointestinale.

Formula: C₁₈H₂₁N₃O₃S

InChI: InChI=1/C11H16ClNO2/c1-9-10(8-12)13-5-4-11(9)15-7-3-6-14-2/h4-5H,3,6-8H2,1-2H3

InChI key: InChIKey=YREYEVIYCVEVJK-UHFFFAOYSA-N

SMILES: S(CC1=C(C)C(OCCCOC)=CC=N1)(=O)C=2NC=3C(N2)=CC=CC3

Sinonimi:

• 117976-89-3
• 1H-Benzimidazole, 2-[[[4-(3-Methoxypropoxy)-3-Methyl-2-Pyridinyl]Methyl]Sulfinyl]-
• 2-(Chloromethyl)-4-(3-Methoxypropoxy)-3-Methylpyridine
• 2-({[4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole
• 2-[4-(3-Methoxy-propoxy)-3-methyl-pyridin-2-ylmethanesulfinyl]-1H-benzoimidazole
• 2-[[[3-Methyl-4-(3-methoxypropoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
• 2-[[[3-Methyl-4-(3-methoxypropoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
• 2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
• 2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
• 2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridyl]methyl]sulfinyl]benzimidazole
• Dexrabeprazol
• Habeprazole
• Ly 307640
• Newprazole
• Pariets
• Pariprazole
• Rabeloc
• Rabemax
• Rabiral
• Rabeprazole
• Rabeprazole Sodium (200 mg) (Sodium 2-[(R)-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl]sulfinyl]benzimidazol-1-ide hydrate)
• 2-[[4-(3-methoxypropoxy)-3-methyl-pyridin-2-yl]methylsulfinyl]-1h-benzoimidazole
• 1H-1,3-benzimidazol-2-yl [4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl sulfoxide-sodium salt
• 2-[(S)-{[4-(3-Methoxypropoxy)-3-Methylpyridin-2-yl]Methane}sulfinyl]-1H-1,3-benzodiazole
• y-307640
• 2-[3-Methyl-4-(3-methoxypropoxy)-2-pyridinylmethylsulfinyl]-1H-benzimidazole
• 2-(CHOLROMETHYL)-4-(3-METHOXYPROPOXY)-3-METHYLPYRIDINE
• Rebeprazole
• 2-(((4-(3-Methoxypropoxy)-3-Methylpyridin-2-yl)Methyl)sulfinyl)-1H-benzo[d]iMidazole

Rabeprazole Sodium Salt

CAS: 117976-89-3, 117976-90-6

Formula: C₁₈H₂₀N₃NaO₃S

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 381.43

Ref: 3B-R0115

Rabeprazole

CAS: 117976-89-3

Formula: C₁₈H₂₁N₃O₃S

Peso molecolare: 359.44

Ref: ST-EA-CP-R5041

1H-​Benzimidazole, 2-​[[[4-​(3-​methoxypropoxy)​-​3-​methyl-​2-​pyridinyl]​methyl]​sulfinyl]​-

CAS: 117976-89-3

Formula: C₁₈H₂₁N₃O₃S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 359.4426

Ref: IN-DA0081D1

Rabeprazole

CAS: 117976-89-3

Rabeprazole

Purezza: ≥95%

Peso molecolare: 359.44g/mol

Ref: 54-BUP06414

Rabeprazole

CAS: 117976-89-3

Formula: C₁₈H₂₁N₃O₃S

Peso molecolare: 359.44

Ref: 7W-GP0914

Rabeprazole

CAS: 117976-89-3

Formula: C₁₈H₂₁N₃O₃S

Colore e forma: Off-White Solid

Peso molecolare: 359.44

Ref: 4Z-R-201

Rabeprazole-d4

CAS: 117976-89-3

Formula: C₁₈H₁₇N₃O₃SD₄

Peso molecolare: 363.47

Ref: 4Z-R-202

Rabeprazole

CAS: 117976-89-3

Rabeprazole (LY307640) is an H+/K+-ATPase inhibitor that inhibits cell proliferation in gastric epithelial cells and can be used in the study of gastric ulcers.

Formula: C₁₈H₂₁N₃O₃S

Purezza: 97.06%

Colore e forma: White To Yellowish Crystalline Powder

Peso molecolare: 359.44

Ref: TM-T19826

Rabeprazole

CAS: 117976-89-3

Rabeprazole is a proton pump inhibitor that suppresses the production of stomach acid by blocking the H+/K+ ATPase enzyme. It is used for the treatment of gastroesophageal reflux disease, peptic ulcers, and Zollinger-Ellison syndrome. Rabeprazole has been shown to be more effective than omeprazole in reducing gastric acid secretion in two-way crossover studies. Rabeprazole also has been shown to inhibit the growth of antibiotic-resistant strains of bacteria. In addition, rabeprazole binds to metal ions like iron and copper, which may affect its pharmacokinetics and efficacy. This drug is currently being investigated as an analytical method for determination of proton pump inhibitors in human serum and urine samples by electrochemical impedance spectroscopy (EIS).

Formula: C₁₈H₂₁N₃O₃S

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 359.44 g/mol

Ref: 3D-IM57864

Rabeprazole

Prodotto controllato

CAS: 117976-89-3

Stability Hygroscopic
Applications Rabeprazole is a partially reversible gastric proton pump inhibitor.
References Morii, M., and Takeguchi, N.: J. Biol. Chem., 268, 21553 (1993); Yasuda, S., et al.: Int. J. Clin. Pharmacol. Ther., 32, 466 (1994); Cloud, M.L., et al.: Dig. Dis. Sci., 43, 993 (1998)

Formula: C₁₈H₂₁N₃O₃S

Colore e forma: Neat

Peso molecolare: 359.44

Ref: TR-R070540