CAS 118292-36-7

Metile (2R,8S)-8-(clorometil)-1,2,3,6,7,8-esaidro-4-idrossi-2-metil-1-osso-6-[(5,6,7-trimetossi-1H-indol-2-il)carbonile]benzo[1,2-b:4,3-b′]dipirrolo-2-carbossilato

Descrizione:

Metile (2R,8S)-8-(clorometil)-1,2,3,6,7,8-esaidro-4-idrossi-2-metil-1-osso-6-[(5,6,7-trimetossi-1H-indol-2-il)carbonile]benzo[1,2-b:4,3-b′]dipirrolo-2-carbossilato, con numero CAS 118292-36-7, è un composto organico complesso caratterizzato dalla sua intricatissima struttura molecolare, che include più gruppi funzionali come idrossile, carbonile ed esteri. Questo composto presenta una struttura a dipirro esahidro, indicando una struttura ciclica saturata, e incorpora un gruppo clorometile, il che suggerisce una reattività potenziale e applicazioni in ulteriori sintesi chimiche. La presenza di trimetossindolo suggerisce attività biologica, possibilmente correlata alla chimica medicinale, poiché i derivati dell'indolo sono spesso associati a varie proprietà farmacologiche. La stereochimica indicata dalla configurazione (2R,8S) evidenzia la natura chirale del composto, che può influenzare le sue interazioni biologiche e l'efficacia. In generale, le caratteristiche strutturali uniche e i gruppi funzionali di questo composto possono contribuire alle sue potenziali applicazioni in prodotti farmaceutici o come sostanza chimica di ricerca nella sintesi organica.

Formula: C₂₆H₂₆ClN₃O₈

InChI: InChI=1S/C26H26ClN3O8/c1-26(25(34)38-5)23(32)18-17-12(9-27)10-30(14(17)8-15(31)20(18)29-26)24(33)13-6-11-7-16(35-2)21(36-3)22(37-4)19(11)28-13/h6-8,12,28-29,31H,9-10H2,1-5H3/t12-,26-/m1/s1

InChI key: InChIKey=BOGFADYROAVVTF-MZHQLVBMSA-N

SMILES: C(Cl)[C@H]1C=2C3=C(N[C@](C(OC)=O)(C)C3=O)C(O)=CC2N(C(=O)C=4NC=5C(C4)=CC(OC)=C(OC)C5OC)C1

Sinonimi:

• (+)-Duocarmycin C₂
• Antibiotic SF 2582A
• Benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylic acid, 8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-, methyl ester, (2R,8S)-
• Benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylic acid, 8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-, methyl ester, (2R-trans)-
• Methyl (2R,8S)-8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylate
• Pyrindamycin
• Sf 2582A
• methyl (2R,8S)-8-(chloromethyl)-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-1,2,3,6,7,8-hexahydropyrrolo[3,2-e]indole-2-carboxylate
• pyrindamycin A
• Duocarmycin C2

Pyrindamycin A

CAS: 118292-36-7

Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.

Formula: C₂₆H₂₆ClN₃O₈

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 543.95

Ref: TM-T12590

Pyrindamycin A

CAS: 118292-36-7

Pyrindamycin A is a natural product that is the product of a fermentation process. It has been shown to have cytotoxic properties and can be used as a chemotherapeutic agent for leukemia and other cancers. Pyrindamycin A is also an antibacterial, with activity against gram-positive and gram-negative bacteria. The mechanism of action involves steric interactions with the target tissue, leading to morphological changes in the bacterial cell wall by inhibiting the synthesis of peptidoglycan. Pyrindamycin A has been shown to inhibit leukemia inhibitory factor (LIF) production in mouse bone marrow cells, which may be due to its ability to bind to DNA. This molecule also has biological properties that are similar to those of monoclonal antibodies, including binding and inhibition of protein synthesis in sensitive cells.

Formula: C₂₆H₂₆ClN₃O₈

Purezza: Min. 95%

Peso molecolare: 544 g/mol

Ref: 3D-TEA29236