CAS 1189987-23-2

Leflunomide-d4

CAS: 1189987-23-2

Formula: C₁₂H₅D₄F₃N₂O₂

Colore e forma: White To Off-White Solid

Peso molecolare: 274.24

Ref: 4Z-L-042

Leflunomide-d4 (phenyl-d4)

CAS: 1189987-23-2

Purezza: 98 atom % D

Colore e forma: White Solid

Peso molecolare: 274.23

Ref: 3U-D6341

Leflunomide-d4

Prodotto controllato

CAS: 1189987-23-2

Applications An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases.This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Vrenken, T., et al.: J. Hepatol., 49, 799 (2008), Mazzucco, G., et al.: Clin. Nephrol., 70, 163 (2008), Davies, M., et al.: J. Med. Chem., 52, 2683 (2009),

Formula: C₁₂D₄H₅F₃N₂O₂

Colore e forma: Neat

Peso molecolare: 274.23

Ref: TR-L322752

Leflunomide-d4

Prodotto controllato

CAS: 1189987-23-2

Leflunomide-d4 is a potent inhibitor of protein interactions, which has been used as a research tool to study the effects of peptides on ion channels. Leflunomide-d4 binds to peptides and interacts with them in vitro. This inhibition can be reversed by adding a specific ligand that competes with the binding site. Leflunomide-d4 is also an activator of the receptor for angiotensin II, which is involved in the regulation of blood pressure. It has been shown to inhibit the activation of some ion channels, such as those for potassium and calcium ions, although it does not inhibit other ion channels such as those for sodium and chloride ions. The molecular weight of leflunomide-d4 is 806 daltons and its CAS number is 1189987-23-2.

Formula: C₁₂H₉F₃N₂O₂

Purezza: Min. 95%

Peso molecolare: 274.23 g/mol

Ref: 3D-PXB98723