CAS 119141-89-8

Omeprazolo

Descrizione:

Omeprazolo è un inibitore della pompa protonica (PPI) utilizzato principalmente per trattare condizioni come la malattia da reflusso gastroesofageo (GERD) e le ulcere peptiche riducendo la produzione di acido gastrico. È caratterizzato dalla sua formula chimica, che include un anello di benzimidazolo, un gruppo metossilico e una porzione di piridina, contribuendo alla sua attività farmacologica. La sostanza è tipicamente somministrata nella sua forma racemica ed è nota per la sua alta lipofilia, che consente un'assorbimento efficace nel tratto gastrointestinale. Omeprazolo è spesso formulato come compresse rivestite enteriche per proteggerlo dalla degradazione nell'ambiente acido dello stomaco, garantendo il rilascio nel pH più neutro dell'intestino. Il suo meccanismo d'azione implica l'inibizione irreversibile dell'enzima H+/K+ ATPasi nelle cellule parietali gastriche, portando a una diminuzione della secrezione di acido gastrico. Omeprazolo è generalmente ben tollerato, sebbene l'uso a lungo termine possa essere associato a determinati rischi, tra cui malassorbimento di nutrienti e infezioni gastrointestinali.

Formula: C₁₇H₁₉N₃O₃S

InChI: InChI=1/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)

InChI key: InChIKey=SUBDBMMJDZJVOS-XMMPIXPASA-N

SMILES: S(CC1=C(C)C(OC)=C(C)C=N1)(=O)C=2NC=3C(N2)=CC=C(OC)C3

Sinonimi:

• (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
• (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole
• (R)-Esomeprazole
• 1H-Benzimidazole, 5-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-
• 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, (R)-
• 1H-Benzimidazole, 6-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-
• 1H-Benzimidazole-1-acetic acid, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, (+)-
• 2-Chloromethyl-3,5-dinmethyl-4-methoxypyridine
• 5-Methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole
• 6-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
• Losec
• Mepral
• Mopral
• Omepral
• Omerprazole
• R-(+)-Omeprazole
• Zoltum
• (S)-OMEPRAZOLE
• R-Omeparazole
• Omeprazole Impurity N
• H 168/68
• 6-methoxy-2-[(R)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
• Omeprazole R-Isomer
• Esomeprazole EP Impurity F
• 2-[(4-METHOXY-3,5-DIMETHYLPYRID-2-YL)-METHYLSULFO]-5-METHOXYBENZIMIDAZOLE
• 5-Methoxy-2-[(R)-[(4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl]sulfinyl]-1H-benziMidazole
• 5-METHOXY-2[(4-METHOXY-3,5-DIMETHYL-2-PYRIDYL)METHYLSULFINYL]-1H-BENZIMIDAZOLE
• EsoMeprazole iMpurity F
• Erythromycine Thiocynate
• Omeprazole Impurity 33
• ANTRA
• GASTROLOC
• omeprazole impurity B (r-omeprazole)
• Omeprazole impurity 18/(R)-Omeprazole/(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
• Omeprazole impurity N (R)-Omeprazole
• (R)-6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole
• GASTROGARD
• PRILOSEC
• 5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL]SULFINYL]-1H-BENZIMIDAZOLE
• Esomeprazole Sodium Impurity 15

1H-Benzimidazole,5-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-

CAS: 119141-89-8

Formula: C₁₇H₁₉N₃O₃S

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 345.4161

Ref: IN-DA00HEY2

(R)-Omeprazole

CAS: 119141-89-8

Formula: C₁₇H₁₉N₃O₃S

Colore e forma: Off-White Solid

Peso molecolare: 345.42

Ref: 4Z-O-024

(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole

CAS: 119141-89-8

Purezza: 95.0%

Peso molecolare: 345.4200134277344

Ref: 10-F448256

(R)-Omeprazole

CAS: 119141-89-8

Omeprazole is a proton pump inhibitor that inhibits gastric acid secretion by binding to the H+/K+ ATPase enzyme in the secretory canaliculi of the parietal cells. Omeprazole has been shown to have a protective effect in animal models against infection with Salmonella enterica serovar Typhimurium, and also protects against ulcers caused by Helicobacter pylori infection. Omeprazole is used as an adjunct treatment for patients with non-infectious gastroesophageal reflux disease (GERD) or active duodenal ulcers. It has also been used for the prevention of stress-related mucosal damage in critically ill patients, although it is not approved for this use. Omeprazole can be administered orally or by injection. When administered orally, omeprazole may cause gastrointestinal side effects such as nausea, abdominal pain, and diarrhea. Omeprazole can interact with other drugs such

Formula: C₁₇H₁₉N₃O₃S

Purezza: Min. 95%

Colore e forma: Off-White Powder

Peso molecolare: 345.42 g/mol

Ref: 3D-FO165430

(R)-Omeprazole

CAS: 119141-89-8

(R)-Omeprazole is a useful organic compound for research related to life sciences. The catalog number is T66287 and the CAS number is 119141-89-8.

Formula: C₁₇H₁₉N₃O₃S

Colore e forma: Solid

Peso molecolare: 345.42

Ref: TM-T66287