CAS 119302-20-4

(2b,3a,5a,16b,17b)-2-(4-morfolinil)-16-(1-pirrolidinil)androstan-3,17-diolo

Descrizione:

La sostanza chimica nota come (2b,3a,5a,16b,17b)-2-(4-morfolinil)-16-(1-pirrolidinil)androstan-3,17-diolo, con il numero CAS 119302-20-4, è un derivato steroideo sintetico. Presenta una struttura steroidea complessa, caratteristica dei composti di androstano, ed è modificata con gruppi funzionali di morfolina e pirrolidina. Queste modifiche possono influenzare le sue proprietà farmacologiche, potenzialmente migliorando la sua interazione con bersagli biologici come i recettori ormonali. La presenza di gruppi idrossilici nelle posizioni 3 e 17 suggerisce che potrebbe mostrare attività biologica correlata agli ormoni steroidei. Gli anelli di morfolina e pirrolidina potrebbero contribuire alla sua solubilità e biodisponibilità, rendendolo di interesse nella chimica medicinale. Questo composto potrebbe essere studiato per le sue potenziali applicazioni terapeutiche, in particolare in aree relative alla regolazione ormonale o come scaffold per lo sviluppo di farmaci. Tuttavia, sarebbero necessari studi dettagliati sulla sua farmacodinamica, farmacocinetica e profilo di sicurezza per comprendere appieno le sue caratteristiche e potenziali usi.

Formula: C₂₇H₄₆N₂O₃

InChI: InChI=1/C27H46N2O3/c1-26-8-7-20-19(21(26)16-22(25(26)31)28-9-3-4-10-28)6-5-18-15-24(30)23(17-27(18,20)2)29-11-13-32-14-12-29/h18-25,30-31H,3-17H2,1-2H3/t18-,19+,20-,21-,22-,23-,24-,25-,26-,27-/m0/s1

InChI key: InChIKey=YKHDYPFPUAWBIW-QJRNWJQSSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@@](CC3)(C[C@H](O)[C@H](C4)N5CCOCC5)[H])(CC1)[H])[H])(C[C@@H]([C@@H]2O)N6CCCC6)[H]

Sinonimi:

• (2B,3A,5A,16B,17B)-2-(4-Morpholinyl)-16-(1-Pyrrolidinyl)Androstane-3,17-Diol(9Ci)
• (2ß ,3A,5A,16ß )-2-(4-Morpholiny)-16-(1-Pyrrolidinyl)Androstane-3,17-Diol
• (2Β,3Α,5Α,16Β,17Β)-2-Morpholin-4-Yl-16-Pyrrolidin-1-Ylandrostane-3,17-Diol
• (2β,3α,5α,16β,17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstan-3,17-diol
• 2,3-Epoxy-1H-Cyclopenta[A]Phenanthrene,Anddrostan-17-Ol Deriv
• 2-(4-Morpholinyl)-16-(1-Pyrrolidinyl)-5-Androstane-3,17-Diol
• 2-(4-Morpholinyl)-16-(pyrrolidin-1-yl)androstane-3,17-diol
• 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol
• 3,17-Dihydroxy-2-(4-Morpholinyl)-16-(1-Pyrroliny)-Androstane
• 3,17-Dihydroxy-2-(4-Morpholinyl)-16-(1-Pyrrolinyl)-Androstane
• Androstane-3,17-Diol, 2-(4-Morpholinyl)-16-(1-Pyrrolidinyl)
• Androstane-3,17-diol, 2-(4-morpholinyl)-16-(1-pyrrolidinyl)-, (2β,3α,5α,16β,17β)-
• Intermediates For Rocuronium Bromide-7
• (2Β,3Α,5Α,16Β,17Β)-2-(4-Morpholinyl)-16-(1-Pyrrolidinyl)Androstane-3,17-Diol
• (2β,3α,5α,16β,17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol
• （2β，3ɑ，5ɑ，16ɑ，17β）-2-（4-morpholinyl）-16-（1-pyrrolidinyl）-androstane-3，17-diol

Desallyl Deacetyl Rocuronium (2β-(Morpholin-4-yl)-16β-(pyrrolidin-1-yl)-5α-androstane-3α,17β-diol)

CAS: 119302-20-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₂₇H₄₆N₂O₃

Colore e forma: Off-White Powder

Peso molecolare: 446.35084

Ref: 45-1A08290

Androstane-3,17-diol, 2-(4-morpholinyl)-16-(1-pyrrolidinyl)-, (2β,3α,5α,16β,17β)-

CAS: 119302-20-4

Formula: C₂₇H₄₆N₂O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 446.6657

Ref: IN-DA000P6V

Rocuronium Bromide EP Impurity G

CAS: 119302-20-4

Formula: C₂₇H₄₆N₂O₃

Colore e forma: White To Off-White Solid

Peso molecolare: 446.68

Ref: 4Z-R-329

(2β,3α,5α,16β,17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol

Prodotto controllato

CAS: 119302-20-4

Applications This compound is used in the synthesis of the neuromuscular blocking agent rocuronium bromide.
References Srinivasan, N. et al.: Orient. J. Chem., 24, 989 (2008);

Formula: C₂₇H₄₆N₂O₃

Colore e forma: Neat

Peso molecolare: 446.67

Ref: TR-M725145

Rocuronium EP Impurity G

CAS: 119302-20-4

Rocuronium EP Impurity G is a drug product that contains an impurity of Rocuronium EP. It is a synthetic, high purity HPLC standard with a purity greater than 99.5% and a CAS number of 119302-20-4. This compound has been researched for use in the development of drugs to treat conditions such as pain, anxiety, and depression. Rocuronium EP Impurity G is a metabolite that has been found in human urine after administration of rocuronium bromide. The metabolism of this substance has not been fully elucidated yet but it may be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid.

Formula: C₂₇H₄₆N₂O₃

Purezza: Min. 95%

Peso molecolare: 446.67 g/mol

Ref: 3D-IR178406

Rocuronium EP Impurity G

CAS: 119302-20-4

Formula: C₂₇H₄₆N₂O₃

Peso molecolare: 446.7

Ref: ST-EA-CP-R78010